diclofenac has been researched along with Arthritis in 93 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Arthritis: Acute or chronic inflammation of JOINTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients aged≥65 years, with osteoarthritis and/or rheumatoid arthritis, at high gastrointestinal (GI) risk who participated in the CONDOR trial (Celecoxib vs." | 9.16 | Efficacy and safety of celecoxib versus diclofenac and omeprazole in elderly arthritis patients: a subgroup analysis of the CONDOR trial. ( Essex, MN; Kellner, HL; Li, C, 2012) |
| " There appeared to be a dose-related increase in CHF with etoricoxib compared with diclofenac, which reached statistical significance when the etoricoxib 90 mg groups (osteoarthritis and rheumatoid arthritis) were pooled." | 9.14 | Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program. ( Brater, DC; Cannon, CP; Curtis, SP; Kaur, A; Krum, H; Laine, L; Smugar, SS; Wang, H; Weir, MR, 2009) |
| " Nimesulide, a selective inhibitor of COX-2, has been shown to relieve pain rapidly in arthritis." | 9.10 | Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis. ( Belton, O; Bresnihan, B; Duffy, T; FitzGerald, D; FitzGerald, O, 2003) |
| "A prespecified pooled intent-to-treat analysis of three double-blind randomised comparisons of etoricoxib (60 or 90 mg daily) and diclofenac (150 mg daily) in 34 701 patients with osteoarthritis or rheumatoid arthritis was done for upper gastrointestinal clinical events (bleeding, perforation, obstruction, or ulcer) and the subset of complicated events (perforation, obstruction, witnessed ulcer bleeding, or significant bleeding)." | 8.84 | Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. ( Cannon, CP; Cryer, B; Curtis, SP; Kaur, A; Laine, L, 2007) |
| " Misoprostol is the only cytoprotective drug found to be effective in the prevention of both gastric and duodenal ulcers associated with NSAIDs." | 8.79 | Efficacy and gastroduodenal safety of a fixed combination of diclofenac and misoprostol in the treatment of arthritis. ( McKenna, F, 1995) |
| "In order to discover and develop drug-like anti-inflammatory agents against arthritis, based on "Hit" we found earlier and to overcome drawbacks of toxicity, twelve series of total 89 novel pyrimidine, pyrazolo[4,3-d]pyrimidine and thieno[3,2-d]pyrimidine derivatives were designed, synthesized and screened for their anti-inflammatory activity against NO and toxicity for normal liver cells (LO2)." | 8.02 | Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis. ( Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL, 2021) |
| "To analyse the antinociceptive interaction between quercetin (QUER) and diclofenac (DIC) in experimental arthritic gout-pain." | 8.02 | Quercetin decreases the antinociceptive effect of diclofenac in an arthritic gout-pain model in rats. ( Ángeles-López, GE; Aviles-Herrera, J; Bustamante-Marquina, A; Déciga-Campos, M; González-Trujano, ME; Navarrete-Vázquez, G; Ventura-Martínez, R, 2021) |
| "Diclofenac sodium is a non-steroidal anti-inflammatory drug of choice to treat arthritis because of its potential anti-inflammatory and analgesic activity." | 7.75 | Development of iron/ethylcellulose (core/shell) nanoparticles loaded with diclofenac sodium for arthritis treatment. ( Arias, JL; Delgado, AV; López-Viota, J; López-Viota, M, 2009) |
| "A 75-year-old woman took aceclofenac (100 mg/day) for 15 days for long-standing arthritis." | 7.72 | [Exudative erythema multiforme with transition to a toxic epidermal necrolysis after taking aceclofenac (Beofenac)]. ( Brinkmeier, T; Frosch, PJ; Ludwig, C, 2003) |
| " The daily maintenance dosage from the fourth week of treatment onwards was 75 mg diclofenac and 500 mg naproxen." | 6.64 | [Long-term comparative study: diclofenac (voltaren) and naproxen (proxen) in arthritis]. ( Placheta, P; Siegmeth, W, 1978) |
| "Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) advocated for use in painful and inflammatory rheumatic and certain non-rheumatic conditions." | 6.16 | Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. ( Sorkin, EM; Todd, PA, 1988) |
| "Patients aged≥65 years, with osteoarthritis and/or rheumatoid arthritis, at high gastrointestinal (GI) risk who participated in the CONDOR trial (Celecoxib vs." | 5.16 | Efficacy and safety of celecoxib versus diclofenac and omeprazole in elderly arthritis patients: a subgroup analysis of the CONDOR trial. ( Essex, MN; Kellner, HL; Li, C, 2012) |
| "We evaluated the relationship between baseline BP and change in BP on CV events (CVEs) in patients receiving NSAIDs or COX-2 inhibitors in the prospective randomized, double-blind, Multinational Etoricoxib and Diclofenac Arthritis Long-term Program (N = 34,701) comparing etoricoxib 60 or 90 mg or diclofenac 150 mg daily for a mean duration of 18 months." | 5.16 | Blood pressure and cardiovascular outcomes in patients taking nonsteroidal antiinflammatory drugs. ( Brater, DC; Cannon, CP; Curtis, SP; Gammaitoni, A; Kaur, A; Krum, H; Laine, L; Peloso, PM; Smugar, SS; Swergold, G; Wang, H; Weir, MR, 2012) |
| " There appeared to be a dose-related increase in CHF with etoricoxib compared with diclofenac, which reached statistical significance when the etoricoxib 90 mg groups (osteoarthritis and rheumatoid arthritis) were pooled." | 5.14 | Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program. ( Brater, DC; Cannon, CP; Curtis, SP; Kaur, A; Krum, H; Laine, L; Smugar, SS; Wang, H; Weir, MR, 2009) |
| "Patients ≥50 years with osteoarthritis or rheumatoid arthritis were randomized to etoricoxib or diclofenac in a prespecified intent-to-treat analysis of three double-blind randomized trials." | 5.14 | Risk factors for NSAID-associated upper GI clinical events in a long-term prospective study of 34 701 arthritis patients. ( Cannon, CP; Cryer, B; Curtis, SP; Kaur, A; Laine, L, 2010) |
| " Nimesulide, a selective inhibitor of COX-2, has been shown to relieve pain rapidly in arthritis." | 5.10 | Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis. ( Belton, O; Bresnihan, B; Duffy, T; FitzGerald, D; FitzGerald, O, 2003) |
| "The clinical efficacy of the two topical analgesics, ketoprofen hydroalcoholic gel (Fastum gel) and diclofenac emulgel, for osteoarthritis of the knee was studied." | 5.08 | Topical analgesics for knee arthrosis: a parallel study of ketoprofen gel and diclofenac emulgel. ( Boonsanong, W; Penkitti, P; Soparat, K; Waikakul, S, 1997) |
| "A prespecified pooled intent-to-treat analysis of three double-blind randomised comparisons of etoricoxib (60 or 90 mg daily) and diclofenac (150 mg daily) in 34 701 patients with osteoarthritis or rheumatoid arthritis was done for upper gastrointestinal clinical events (bleeding, perforation, obstruction, or ulcer) and the subset of complicated events (perforation, obstruction, witnessed ulcer bleeding, or significant bleeding)." | 4.84 | Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. ( Cannon, CP; Cryer, B; Curtis, SP; Kaur, A; Laine, L, 2007) |
| " Misoprostol is the only cytoprotective drug found to be effective in the prevention of both gastric and duodenal ulcers associated with NSAIDs." | 4.79 | Efficacy and gastroduodenal safety of a fixed combination of diclofenac and misoprostol in the treatment of arthritis. ( McKenna, F, 1995) |
| " The effect of 10% AKBA at 20 mg/kg and 40 mg/kg was evaluated in the FCA induced arthritis animal model alone and combined with methotrexate (MTX) at 2 mg/kg b." | 4.12 | Bioavailability, anti-inflammatory and anti-arthritic effect of Acetyl Keto Boswellic acid and its combination with methotrexate in an arthritic animal model. ( Alqahtani, SS; Alshahrani, S; Banji, D; Banji, OJF; Rashida, S, 2022) |
| "To analyse the antinociceptive interaction between quercetin (QUER) and diclofenac (DIC) in experimental arthritic gout-pain." | 4.02 | Quercetin decreases the antinociceptive effect of diclofenac in an arthritic gout-pain model in rats. ( Ángeles-López, GE; Aviles-Herrera, J; Bustamante-Marquina, A; Déciga-Campos, M; González-Trujano, ME; Navarrete-Vázquez, G; Ventura-Martínez, R, 2021) |
| "In order to discover and develop drug-like anti-inflammatory agents against arthritis, based on "Hit" we found earlier and to overcome drawbacks of toxicity, twelve series of total 89 novel pyrimidine, pyrazolo[4,3-d]pyrimidine and thieno[3,2-d]pyrimidine derivatives were designed, synthesized and screened for their anti-inflammatory activity against NO and toxicity for normal liver cells (LO2)." | 4.02 | Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis. ( Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL, 2021) |
| " In a cohort study comparing the risk of upper gastrointestinal complications in celecoxib or traditional NSAIDs (diclofenac, ibuprofen) initiators with rheumatoid arthritis and osteoarthritis, we (1) aggregated medications and International Classification of Diseases-9 (ICD-9) diagnoses into hierarchies of the Anatomical Therapeutic Chemical classification (ATC) and the Clinical Classification Software (CCS), respectively, and (2) sampled the full cohort using techniques validated by simulations to create 9,600 samples to compare 16 aggregation scenarios across 50% and 20% samples with varying outcome incidence and exposure prevalence." | 3.79 | Effects of aggregation of drug and diagnostic codes on the performance of the high-dimensional propensity score algorithm: an empirical example. ( Beach, KJ; Brookhart, MA; Layton, JB; Le, HV; Poole, C; Schoenbach, VJ; Stürmer, T, 2013) |
| "We investigated the effects of exogenous phosphatidylcholine (PC) and non-steroidal diclofenac supplementation on polymorphonuclear cell influx in carrageenan-induced arthritis in rats." | 3.75 | Anti-inflammatory effects of phosphatidylcholine in neutrophil leukocyte-dependent acute arthritis in rats. ( Boros, M; Eros, G; Ghyczy, M; Gurabi, D; Hartmann, P; Horváth, G; Németh, I; Szabó, A, 2009) |
| "Diclofenac sodium is a non-steroidal anti-inflammatory drug of choice to treat arthritis because of its potential anti-inflammatory and analgesic activity." | 3.75 | Development of iron/ethylcellulose (core/shell) nanoparticles loaded with diclofenac sodium for arthritis treatment. ( Arias, JL; Delgado, AV; López-Viota, J; López-Viota, M, 2009) |
| "To estimate the net cardiovascular (CV) (coronary heart disease, stroke, congestive heart failure), and gastrointestinal (GI) (peptic ulcer complications) risk-benefit public health impact of the use of celecoxib compared to non-selective NSAIDs in the arthritis population." | 3.74 | Quantitative assessment of the gastrointestinal and cardiovascular risk-benefit of celecoxib compared to individual NSAIDs at the population level. ( Castellsague, J; Maguire, A; Perez-Gutthann, S; Varas-Lorenzo, C, 2007) |
| "A 75-year-old woman took aceclofenac (100 mg/day) for 15 days for long-standing arthritis." | 3.72 | [Exudative erythema multiforme with transition to a toxic epidermal necrolysis after taking aceclofenac (Beofenac)]. ( Brinkmeier, T; Frosch, PJ; Ludwig, C, 2003) |
| "We present a 28-year-old patient with liquefying idiopathic lobular panniculitis, a variant of the Weber-Christian's disease and intermittent episodes of arthritis in the left foot refractory to sequential treatment with anti-inflammatory drugs, high doses of prednisone, chloroquine, dapsone, colchicine, cyclosporine and methotrexate." | 3.69 | [Refractory idiopathic liquefying panniculitis]. ( Antón Badiola, I; Ferreiro Seoane, JL; Formigo Rodríguez, E; Gómez Rodríguez, N, 1995) |
| "The well known nonsteroidal antiinflammatory drugs (NSAID) diclofenac, piroxicam and tiaprofenic acid as well as the corticosteroid prednisolone, were examined for their effect on injury to knee joint structures evoked by a developing murine antigen induced arthritis." | 3.67 | Impact of NSAIDS on murine antigen induced arthritis. I. Investigation of antiinflammatory and chondroprotective effects. ( de Vries, BJ; van den Berg, WB, 1989) |
| "A dermatomyositis-like syndrome developed in a patient treated with a nonsteroidal anti-inflammatory agent (NSAI), niflumic acid, and regressed after the cessation of treatment." | 3.67 | Dermatomyositis-like syndrome induced by nonsteroidal anti-inflammatory agents. ( Bonerandi, JJ; Collet, AM; Grob, JJ, 1989) |
| "Sequential potentiation of antiinflammatory activity of dexamethasone was obtained by co-administration of diclofenac-Na (and indomethacin), but not of phenylbutazone and, apparently, of acetylsalicylic acid (ASA) in the carrageenin rat paw edema." | 3.67 | On steroid-saving drug combinations in carrageenin paw edema and adjuvant arthritis. ( Bekemeier, H; Hirschelmann, R, 1986) |
| " When the possibility of poor compliance and the potential adverse effects of misoprostol are considered, rebamipide appears to be a clinically effective and safe alternative." | 2.79 | Preventive efficacy and safety of rebamipide in nonsteroidal anti-inflammatory drug-induced mucosal toxicity. ( Cho, CS; Kang, YM; Kim, JH; Kim, SK; Lee, DH; Lee, SK; Lee, ST; Lee, YC; Park, SH; Park, W; Park, YW; Rew, JS; Yoo, WH, 2014) |
| " In a comparison of two non-steroidal anti-inflammatory agents in this condition we attempted to overcome the difficulties by using a run-in period during which the dosage of one of the trial drugs was adjusted to suit the individual patient." | 2.65 | The run-in period in trial design: a comparison of two non-steroidal anti-inflammatory agents in psoriatic arthropathy. ( Bird, HA; Fowler, PD; Leatham, PA; Wright, V, 1982) |
| " The daily maintenance dosage from the fourth week of treatment onwards was 75 mg diclofenac and 500 mg naproxen." | 2.64 | [Long-term comparative study: diclofenac (voltaren) and naproxen (proxen) in arthritis]. ( Placheta, P; Siegmeth, W, 1978) |
| "Luteolin (LUT) is a promising molecule with potential anti-arthritic activity." | 1.43 | Enhanced transdermal delivery of luteolin via non-ionic surfactant-based vesicle: quality evaluation and anti-arthritic assessment. ( Abidin, L; Aqil, M; Imam, SS; Khurana, D; Mujeeb, M, 2016) |
| " Etoricoxib is partly metabolised by the cytochrome P450 isoenzyme CYP 3A4 and increases the bioavailability of ethinylestradiol." | 1.34 | Etoricoxib: new drug. Avoid using cox-2 inhibitors for pain. ( , 2007) |
| "Celecoxib users were 4." | 1.32 | Persistence with COX-2 inhibitors in managed care: an analysis of claims data. ( Harley, C; Wagner, S, 2003) |
| "Electrolyte disorders and acute renal failure are observed more frequently in patients with risk factors." | 1.31 | [Renal tolerance of selective inhibitors of cyclooxygenase type 2]. ( Deray, G, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (23.66) | 18.7374 |
| 1990's | 17 (18.28) | 18.2507 |
| 2000's | 35 (37.63) | 29.6817 |
| 2010's | 15 (16.13) | 24.3611 |
| 2020's | 4 (4.30) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, LZ | 1 |
| Shu, HY | 1 |
| Wu, J | 1 |
| Yu, YL | 1 |
| Ma, D | 1 |
| Huang, X | 1 |
| Liu, MM | 1 |
| Liu, XH | 1 |
| Shi, JB | 1 |
| Banji, D | 1 |
| Banji, OJF | 1 |
| Rashida, S | 1 |
| Alshahrani, S | 1 |
| Alqahtani, SS | 1 |
| Ferreira-Silva, J | 1 |
| Morais, R | 1 |
| Macedo, G | 1 |
| Ventura-Martínez, R | 1 |
| Déciga-Campos, M | 1 |
| Bustamante-Marquina, A | 1 |
| Ángeles-López, GE | 1 |
| Aviles-Herrera, J | 1 |
| González-Trujano, ME | 1 |
| Navarrete-Vázquez, G | 1 |
| Kreutzkamp, B | 1 |
| Suresh, E | 1 |
| Le, HV | 1 |
| Poole, C | 1 |
| Brookhart, MA | 1 |
| Schoenbach, VJ | 1 |
| Beach, KJ | 1 |
| Layton, JB | 1 |
| Stürmer, T | 1 |
| Tofield, A | 1 |
| Kim, JH | 1 |
| Park, SH | 1 |
| Cho, CS | 1 |
| Lee, ST | 1 |
| Yoo, WH | 1 |
| Kim, SK | 1 |
| Kang, YM | 1 |
| Rew, JS | 1 |
| Park, YW | 1 |
| Lee, SK | 1 |
| Lee, YC | 1 |
| Park, W | 1 |
| Lee, DH | 1 |
| Abidin, L | 1 |
| Mujeeb, M | 1 |
| Imam, SS | 1 |
| Aqil, M | 1 |
| Khurana, D | 1 |
| Iannitti, T | 1 |
| McDermott, MF | 1 |
| Laurino, C | 1 |
| Malagoli, A | 1 |
| Palmieri, B | 1 |
| Krum, H | 2 |
| Curtis, SP | 4 |
| Kaur, A | 4 |
| Wang, H | 2 |
| Smugar, SS | 2 |
| Weir, MR | 2 |
| Laine, L | 4 |
| Brater, DC | 2 |
| Cannon, CP | 4 |
| Lazebnik, LB | 1 |
| Drozdov, VN | 1 |
| Kim, VA | 1 |
| Arias, JL | 1 |
| López-Viota, M | 1 |
| López-Viota, J | 1 |
| Delgado, AV | 1 |
| Hartmann, P | 1 |
| Szabó, A | 1 |
| Eros, G | 1 |
| Gurabi, D | 1 |
| Horváth, G | 1 |
| Németh, I | 1 |
| Ghyczy, M | 1 |
| Boros, M | 1 |
| Shyni, GL | 1 |
| Ratheesh, M | 1 |
| Sindhu, G | 1 |
| Helen, A | 1 |
| Titos-Arcos, JC | 1 |
| Hallal, H | 1 |
| Andrade, RJ | 1 |
| Gálvez, J | 1 |
| Kampen, WU | 1 |
| Czech, N | 1 |
| von Forstner, C | 1 |
| Henze, E | 1 |
| Möller, B | 1 |
| Bartsch, MS | 1 |
| Cryer, B | 3 |
| El-Ghazaly, MA | 1 |
| El-Naby, DH | 1 |
| Khayyal, MT | 1 |
| Kumar, VL | 1 |
| Chaudhary, P | 1 |
| Ramos, MV | 1 |
| Mohan, M | 1 |
| Matos, MP | 1 |
| Paiva, AA | 1 |
| Castro, AJ | 1 |
| Nascimento, MS | 1 |
| Will, LS | 1 |
| Santos, ND | 1 |
| Araújo, RM | 1 |
| Xavier, CA | 1 |
| Rocha, FA | 1 |
| Leite, EL | 1 |
| Swergold, G | 1 |
| Gammaitoni, A | 1 |
| Peloso, PM | 1 |
| Kellner, HL | 1 |
| Li, C | 1 |
| Essex, MN | 1 |
| Chan, FK | 4 |
| Hung, LC | 2 |
| Suen, BY | 2 |
| Wu, JC | 3 |
| Lee, KC | 1 |
| Leung, VK | 1 |
| Hui, AJ | 2 |
| To, KF | 3 |
| Leung, WK | 3 |
| Wong, VW | 2 |
| Chung, SC | 2 |
| Sung, JJ | 3 |
| Graham, DY | 1 |
| Ludwig, C | 1 |
| Brinkmeier, T | 1 |
| Frosch, PJ | 1 |
| Tachibana, M | 1 |
| Inoue, N | 1 |
| Yoshida, E | 1 |
| Matsui, M | 1 |
| Ukai, Y | 1 |
| Yano, J | 1 |
| Roseau, G | 1 |
| Chaussade, S | 1 |
| Duffy, T | 1 |
| Belton, O | 1 |
| Bresnihan, B | 1 |
| FitzGerald, O | 1 |
| FitzGerald, D | 1 |
| Harley, C | 1 |
| Wagner, S | 1 |
| Altaykan, A | 1 |
| Erkin, G | 1 |
| Boztepe, G | 1 |
| Gököz, A | 1 |
| Lee, YT | 1 |
| Hollenz, M | 1 |
| Labenz, J | 1 |
| Zeidler, H | 1 |
| May, M | 1 |
| Uberall, MA | 1 |
| Vergin, H | 1 |
| Schafroth Török, S | 1 |
| Lorette, G | 1 |
| Despert, F | 1 |
| Varas-Lorenzo, C | 1 |
| Maguire, A | 1 |
| Castellsague, J | 1 |
| Perez-Gutthann, S | 1 |
| Rodríguez, LA | 1 |
| Patrignani, P | 1 |
| Heilborn, U | 1 |
| Rost, BR | 1 |
| Arborelius, L | 1 |
| Brodin, E | 1 |
| Duh, D | 1 |
| Vandevijver, A | 1 |
| Peura, D | 1 |
| Wilcox, CM | 1 |
| Niculescu, L | 1 |
| Berger, M | 1 |
| Hawkey, CJ | 1 |
| Weinstein, WM | 1 |
| Stricker, K | 1 |
| Murphy, V | 1 |
| Richard, D | 1 |
| Krammer, G | 1 |
| Rebuli, R | 1 |
| Inoue, M | 1 |
| Akimoto, T | 1 |
| Saito, O | 1 |
| Ando, Y | 1 |
| Muto, S | 1 |
| Kusano, E | 1 |
| Obel, AO | 1 |
| Leatham, PA | 1 |
| Bird, HA | 1 |
| Wright, V | 1 |
| Fowler, PD | 1 |
| Baroni, L | 1 |
| Comoglio, T | 1 |
| Trombetta, N | 1 |
| Cornelli, U | 1 |
| Machtey, I | 1 |
| Ouaknine, L | 1 |
| Sandowski, U | 1 |
| Ratcliffe, WA | 1 |
| Hazelton, RA | 1 |
| Thomson, JA | 1 |
| Ratcliffe, JG | 1 |
| Kafarnik, D | 1 |
| Locatelli, L | 2 |
| Sacerdote, P | 2 |
| Mantegazza, P | 1 |
| Panerai, AE | 2 |
| Kiff, PS | 1 |
| Stead, H | 1 |
| Morant, SV | 1 |
| Shield, MJ | 1 |
| McKenna, F | 1 |
| Gómez Rodríguez, N | 1 |
| Formigo Rodríguez, E | 1 |
| Ferreiro Seoane, JL | 1 |
| Antón Badiola, I | 1 |
| Geis, GS | 1 |
| Pohl, LR | 1 |
| Martin, JL | 1 |
| Hargus, SJ | 1 |
| Rosenthal, M | 1 |
| Bahous, I | 2 |
| Pallarés Querol, M | 1 |
| Wittenberg, RH | 1 |
| Willburger, RE | 1 |
| Kleemeyer, KS | 1 |
| Peskar, BA | 1 |
| Waikakul, S | 1 |
| Penkitti, P | 1 |
| Soparat, K | 1 |
| Boonsanong, W | 1 |
| Silverstein, FE | 1 |
| Steinbrück, K | 1 |
| Mas, C | 1 |
| Menahem, S | 1 |
| Goldstein, JL | 1 |
| Larson, LR | 1 |
| Yamashita, BD | 1 |
| Tunçay, M | 1 |
| Caliş, S | 1 |
| Kaş, HS | 1 |
| Ercan, MT | 1 |
| Peksoy, I | 1 |
| Hincal, AA | 1 |
| Brune, K | 1 |
| Lemmer, B | 1 |
| Sadowski, T | 1 |
| Steinmeyer, J | 2 |
| Deray, G | 1 |
| Simon, LS | 1 |
| Yung, MY | 1 |
| Kwok, T | 1 |
| Hui, Y | 1 |
| Chan, HL | 1 |
| Chan, CS | 1 |
| Hui, E | 1 |
| Woo, J | 1 |
| Miura, T | 1 |
| Giancola, R | 1 |
| Nannei, A | 1 |
| Siegmeth, W | 1 |
| Placheta, P | 1 |
| Burton-Wurster, N | 1 |
| Lust, G | 1 |
| Jajić, I | 1 |
| Jajić, Z | 1 |
| Penkov, N | 1 |
| Markov, I | 1 |
| Petrova, R | 1 |
| Radeva, L | 1 |
| de Vries, BJ | 1 |
| van den Berg, WB | 1 |
| Grob, JJ | 1 |
| Collet, AM | 1 |
| Bonerandi, JJ | 1 |
| Attal, N | 2 |
| Guilbaud, G | 2 |
| Bekemeier, H | 1 |
| Hirschelmann, R | 1 |
| Kayser, V | 1 |
| Eschalier, A | 1 |
| Benoist, JM | 1 |
| Todd, PA | 1 |
| Sorkin, EM | 1 |
| Chan, KK | 1 |
| Vyas, KH | 1 |
| Brandt, KD | 1 |
| Brenner, P | 1 |
| Tizian, C | 1 |
| Wouters, JM | 1 |
| van Rijswijk, MH | 1 |
| van de Putte, LB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Multicenter Study to Evaluate the Tolerability and Effectiveness of Etoricoxib 90 mg q.d. vs. Diclofenac Sodium 50 mg t.i.d. in Patients With Osteoarthritis[NCT00092703] | Phase 3 | 6,000 participants | Interventional | 2002-06-27 | Completed | ||
| A Randomized, Double-Blind, Multicenter Study to Evaluate the Tolerability and Effectiveness of Etoricoxib 90 mg q.d. vs. Diclofenac Sodium 75 mg b.i.d. in Patients With Rheumatoid Arthritis[NCT00092742] | Phase 3 | 4,086 participants (Actual) | Interventional | 2003-02-28 | Completed | ||
| A Randomized, Double-Blind, Active-Comparator-Controlled, Parallel-Group Study to Evaluate the Safety of Etoricoxib in Patients With Osteoarthritis or Rheumatoid Arthritis[NCT00250445] | Phase 3 | 23,498 participants (Actual) | Interventional | 2003-01-31 | Completed | ||
| A 12-Week, Randomized, Placebo- and Active-Comparator-Controlled, Parallel-Group, Double-Blind Study to Assess the Safety and Efficacy of Etoricoxib 30 mg Versus Ibuprofen 2400 mg in Patients With Osteoarthritis (Study 1)[NCT00269191] | Phase 3 | 528 participants (Actual) | Interventional | 2003-02-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for diclofenac and Arthritis
| Article | Year |
|---|---|
[Aceclofenac-induced acute cholestatic lesion].
Topics: Acute Disease; Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspartate A | 2010 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; | 1982 |
Efficacy and gastroduodenal safety of a fixed combination of diclofenac and misoprostol in the treatment of arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Drug Combin | 1995 |
Arthrotec: a therapeutic option in the management of arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; Double-Bli | 1993 |
Improving the gastrointestinal safety of NSAIDs: the development of misoprostol--from hypothesis to clinical practice.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Diclofenac; Drug Combinations | 1998 |
Prevention of nonsteroidal anti-inflammatory drug-induced gastropathy: clinical and economic implications of a single-tablet formulation of diclofenac/misoprostol.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Canada; Cost of Illness; Diclofenac; Drug Combin | 1998 |
COX-2 inhibitors. Are they nonsteroidal anti-inflammatory drugs with a better safety profile?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 In | 2001 |
Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; D | 1988 |
23 trials available for diclofenac and Arthritis
| Article | Year |
|---|---|
Preventive efficacy and safety of rebamipide in nonsteroidal anti-inflammatory drug-induced mucosal toxicity.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Butanon | 2014 |
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program.
Topics: Aged; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib | 2009 |
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program.
Topics: Aged; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib | 2009 |
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program.
Topics: Aged; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib | 2009 |
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program.
Topics: Aged; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib | 2009 |
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program.
Topics: Aged; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib | 2009 |
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program.
Topics: Aged; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib | 2009 |
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program.
Topics: Aged; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib | 2009 |
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program.
Topics: Aged; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib | 2009 |
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program.
Topics: Aged; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib | 2009 |
[Efficiency of famotidin in prophylaxis of NSAIDs-induced gastropathy: result of multicenter research ZASLON-1 (protection of gastric mucosa from non-steroidal anti-inflammatory drugs].
Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Dic | 2009 |
Risk factors for NSAID-associated upper GI clinical events in a long-term prospective study of 34 701 arthritis patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cyclooxygenase 2 | 2010 |
Blood pressure and cardiovascular outcomes in patients taking nonsteroidal antiinflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Blood Pressure; Body Weight; Comorbidity; | 2012 |
Efficacy and safety of celecoxib versus diclofenac and omeprazole in elderly arthritis patients: a subgroup analysis of the CONDOR trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase 2 Inhibitors; Di | 2012 |
Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Celecoxib; Cyclooxygenase 2; | 2002 |
Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis.
Topics: Acute Disease; Administration, Oral; Arthralgia; Arthritis; Cyclooxygenase 1; Cyclooxygenase 2; Dicl | 2003 |
Celecoxib versus diclofenac plus omeprazole in high-risk arthritis patients: results of a randomized double-blind trial.
Topics: Adult; Aged; Arthritis; Celecoxib; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Dyspe | 2004 |
Clinical trial: comparison of the gastrointestinal safety of lumiracoxib with traditional nonselective nonsteroidal anti-inflammatory drugs early after the initiation of treatment--findings from the Therapeutic Arthritis Research and Gastrointestinal Even
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cyclooxygenase | 2008 |
The run-in period in trial design: a comparison of two non-steroidal anti-inflammatory agents in psoriatic arthropathy.
Topics: Adult; Anti-Inflammatory Agents; Arthritis; Clinical Trials as Topic; Diclofenac; Double-Blind Metho | 1982 |
[Sodium diclofenac in the ambulatory therapy of joint inflammation and pain. Multicentric open-ended research performed by 223 Italian physicians].
Topics: Adult; Aged; Ambulatory Care; Arthritis; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac | 1982 |
Arthrotec, diclofenac and ibuprofen in general practice.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Drug Combinations; Female; Hum | 1994 |
A controlled clinical study on the new topical dosage form of DHEP plasters in patients suffering from localized inflammatory diseases.
Topics: Administration, Cutaneous; Arthritis; Diclofenac; Female; Humans; Male; Middle Aged; Pain Measuremen | 1993 |
Topical analgesics for knee arthrosis: a parallel study of ketoprofen gel and diclofenac emulgel.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Chi-Square Distribution; Diclofenac; Female; Gel | 1997 |
Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Delayed-Action Preparations; | 2002 |
[Diflunisal--a new long-acting nonsteroidal antirheumatic. Clinical trial versus Diclofenac (author's transl)].
Topics: Aged; Arthritis; Aspirin; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Female; Humans; Mal | 1979 |
[A new anti-rheumatic drug in orthopedics].
Topics: Adolescent; Adult; Aged; Arthritis; Child; Clinical Trials as Topic; Diclofenac; Female; Humans; Joi | 1979 |
[Long-term comparative study: diclofenac (voltaren) and naproxen (proxen) in arthritis].
Topics: Arthritis; Diclofenac; Drug Evaluation; Hip Joint; Humans; Knee Joint; Naproxen; Phenylacetates | 1978 |
[Effectiveness and safety of Lubor capsules in patients with gonarthrosis and extra-articular rheumatism].
Topics: Adult; Aged; Arthritis; Capsules; Diclofenac; Double-Blind Method; Female; Humans; Knee Joint; Male; | 1991 |
[Comparative clinical study of the efficacy of Pharmachem's feloran gel and voltaren emulsion-gel in the combined treatment of arthrosis-arthritis of the knee joint].
Topics: Adult; Aged; Aged, 80 and over; Arthritis; Diclofenac; Emulsions; Female; Gels; Humans; Knee Joint; | 1989 |
Diclofenac.
Topics: Arthritis; Clinical Trials as Topic; Diclofenac; Drug Interactions; Humans | 1988 |
Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; D | 1988 |
62 other studies available for diclofenac and Arthritis
| Article | Year |
|---|---|
Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis.
Topics: Administration, Oral; Animals; Arthritis; Cells, Cultured; Dimerization; Disease Models, Animal; Dos | 2021 |
Bioavailability, anti-inflammatory and anti-arthritic effect of Acetyl Keto Boswellic acid and its combination with methotrexate in an arthritic animal model.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Bilirubin; Biological Availability; Boswellia; Diclofe | 2022 |
An Unusual Cause of Regurgitation and Heartburn In a Patient With Fundoplication.
Topics: Arthritis; Biopsy; Diclofenac; Endoscopy, Digestive System; Esophageal Mucosa; Esophagitis; Female; | 2020 |
Quercetin decreases the antinociceptive effect of diclofenac in an arthritic gout-pain model in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis; Diclofenac; Dis | 2021 |
[In process].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Hip; Humans; Knee; Pain; Treatment O | 2017 |
Problem based review: The patient with acute monoarthritis.
Topics: Acute Disease; Adult; Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; A | 2013 |
Effects of aggregation of drug and diagnostic codes on the performance of the high-dimensional propensity score algorithm: an empirical example.
Topics: Adolescent; Adult; Aged; Algorithms; Arthritis; Celecoxib; Confounding Factors, Epidemiologic; Cyclo | 2013 |
Common analgesics 'pose cardiac risk'.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Heart Dise | 2014 |
Enhanced transdermal delivery of luteolin via non-ionic surfactant-based vesicle: quality evaluation and anti-arthritic assessment.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Chemistry, P | 2016 |
Corticosteroid transdermal delivery significantly improves arthritis pain and functional disability.
Topics: Administration, Cutaneous; Anti-Inflammatory Agents; Arthritis; Betamethasone Valerate; C-Reactive P | 2017 |
New topical anti-inflammatory drugs may curb arthritis pain.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Humans; Pai | 2008 |
Development of iron/ethylcellulose (core/shell) nanoparticles loaded with diclofenac sodium for arthritis treatment.
Topics: Absorption; Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cellulose; Chemistry, Ph | 2009 |
Anti-inflammatory effects of phosphatidylcholine in neutrophil leukocyte-dependent acute arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; H | 2009 |
Anti-inflammatory and antioxidant effects of Jeevaneeya Rasayana: an ayurvedic polyherbal formulation on acute and chronic models of inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arachidonate 5-Lipoxygenase; Arthrit | 2010 |
Radiosynoviorthesis of the temporomandibular joint--initial clinical application.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Female; Gamma Cameras; Humans; Metho | 2009 |
The influence of irradiation on the potential chondroprotective effect of aqueous extract of propolis in rats.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Exper | 2011 |
Protective effect of proteins derived from the latex of Calotropis procera against inflammatory hyperalgesia in monoarthritic rats.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Calotropis; Carrageenan; Diclofenac; Edema; Female; Fr | 2011 |
Antioxidant and anti-inflammatory effect of polysaccharides from Lobophora variegata on zymosan-induced arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis; Diclofenac; Edema; Hydroxyl Radical; Imm | 2011 |
NSAIDs, Helicobacter pylori, and Pandora's Box.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Celecoxib; Cyclooxygenase 2; | 2002 |
[Exudative erythema multiforme with transition to a toxic epidermal necrolysis after taking aceclofenac (Beofenac)].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Erythema Multiforme; Female; H | 2003 |
Anti-inflammatory effect and low ulcerogenic activity of etodolac, a cyclooxygenase-2 selective non-steroidal anti-inflammatory drug, on adjuvant-induced arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; | 2003 |
[Collagenous colitis complicated by multiple ulcerations].
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Biopsy; Chronic Disease | 2003 |
Persistence with COX-2 inhibitors in managed care: an analysis of claims data.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 In | 2003 |
Interstitial granulomatous dermatitis with arthritis.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Biopsy; Clemastine; Der | 2004 |
COX-2-specific inhibitor or proton pump inhibitor plus traditional NSAID: is either approach sufficient for patients at highest risk of NSAID-induced ulcers?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxyge | 2004 |
[Gastrointestinal complications under NSAID treatment in the doctor's office].
Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Dicl | 2004 |
NICE risk factors for gastrointestinal adverse events in diclofenac users in general practice in Germany: comment on the article of Thompson et al.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Fam | 2006 |
[Arthritis and papulo-pustular skin changes].
Topics: Acquired Hyperostosis Syndrome; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diagnosis | 2006 |
[HLA-B27-associated dactylitis in a child].
Topics: Adolescent; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diagnosis, Differential | 2006 |
Quantitative assessment of the gastrointestinal and cardiovascular risk-benefit of celecoxib compared to individual NSAIDs at the population level.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular D | 2007 |
The ever growing story of cyclo-oxygenase inhibition.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Cyclooxygenase Inhibito | 2006 |
Arthritis-induced increase in cholecystokinin release in the rat anterior cingulate cortex is reversed by diclofenac.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cholecystokinin; | 2007 |
[Lumiracoxib--Prexigem].
Topics: Arthritis; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Pain | 2007 |
Etoricoxib: new drug. Avoid using cox-2 inhibitors for pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Clinical | 2007 |
Response to Ray and colleagues: the called-for large clinical trial is already ongoing.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Celecoxib; Diclofenac; Humans | 2008 |
Successful relatively low-dose corticosteroid therapy for diclofenac-induced acute interstitial nephritis with severe renal failure.
Topics: Acetylglucosaminidase; Acute Disease; Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-S | 2008 |
[Diclofenac versus ketoprofen in degenerative joint disease].
Topics: Adult; Aged; Arthritis; Diclofenac; Double-Blind Method; Humans; Ketoprofen; Middle Aged; Phenylacet | 1980 |
The effect of fenclofenac on thyroid function tests in vivo and in vitro.
Topics: Adult; Aged; Arthritis; Diagnostic Errors; Diclofenac; Female; Humans; Male; Middle Aged; Phenylacet | 1980 |
[Clinical experiences with sodium diclofenac in high dosage in the treatment of chronic polyarthritis].
Topics: Adult; Aged; Arthritis; Chronic Disease; Diclofenac; Dose-Response Relationship, Drug; Female; Human | 1980 |
Effect of ibuprofen and diclofenac on the chemotaxis induced by substance P and transforming growth factor-beta on human monocytes and polymorphonuclear cells.
Topics: Arthritis; Chemotaxis; Diclofenac; Humans; Ibuprofen; In Vitro Techniques; Monocytes; Neutrophils; S | 1993 |
Inhibitory effect of NSAIDs on the chemotaxis induced by substance P on human monocytes and polymorphonuclear cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Chemotaxis, Leukocyte; Diclofenac; Huma | 1993 |
[Refractory idiopathic liquefying panniculitis].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Azathioprine; Diclofenac; Drug Resistance | 1995 |
Immunochemical methods of studying the mechanism of diclofenac-induced hepatitis [corrected].
Topics: Arthritis; Chemical and Drug Induced Liver Injury; Diclofenac; Humans; Immunohistochemistry | 1994 |
[Aceclofenac and mental confusion].
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Confusion; Diclofenac; | 1994 |
In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases.
Topics: Arthritis; Arthritis, Rheumatoid; Bone and Bones; Cartilage, Articular; Chondrocalcinosis; Culture T | 1993 |
[Cartilage damage/gonarthrosis. Diagnosis and therapy].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cartilage, Articular; Diclofenac; Humans; Knee I | 1998 |
Premature in utero closure of the ductus arteriosus following maternal ingestion of sodium diclofenac.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cesarean Section; Constriction, Pathologi | 1999 |
Diclofenac sodium incorporated PLGA (50:50) microspheres: formulation considerations and in vitro/in vivo evaluation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Biocompatible Materials; Biodegradation | 2000 |
[Is homeopathic medicine equivalent to diclofenac?! An opinion statement against misleading].
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Double-Blind | 2000 |
Minocycline inhibits the production of inducible nitric oxide synthase in articular chondrocytes.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cattle; Cell Sur | 2001 |
[Renal tolerance of selective inhibitors of cyclooxygenase type 2].
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Animals; Anti-Inflammatory Agents, Non-Steroida | 2001 |
Long-term tolerability study of Voltaren.
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Blood Cell Count; Blood Proteins; Diclofenac; Female; | 1975 |
Effects of three antiarthritic drugs on fibronectin and keratan sulfate synthesis by cultured canine articular cartilage chondrocytes.
Topics: Animals; Arthritis; Cartilage, Articular; Cells, Cultured; Diclofenac; DNA; Dogs; Fibronectins; Glyc | 1992 |
Impact of NSAIDS on murine antigen induced arthritis. I. Investigation of antiinflammatory and chondroprotective effects.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Cartilage, Art | 1989 |
Dermatomyositis-like syndrome induced by nonsteroidal anti-inflammatory agents.
Topics: Administration, Oral; Adult; Arthritis; Dermatomyositis; Diclofenac; Female; Humans; Nicotinic Acids | 1989 |
[Analgesic action of sodium diclofenac: behavioral and electrophysiological study in normal and polyarthritic rats].
Topics: Animals; Arthritis; Behavior, Animal; Diclofenac; Disease Models, Animal; Dose-Response Relationship | 1988 |
On steroid-saving drug combinations in carrageenin paw edema and adjuvant arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Dexame | 1986 |
Behavioural and electrophysiological evidence for an analgesic effect of a non-steroidal anti-inflammatory agent, sodium diclofenac.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Dose-Res | 1988 |
In vitro protein binding of diclofenac sodium in plasma and synovial fluid.
Topics: Albumins; Arthritis; Blood Proteins; Diclofenac; Humans; In Vitro Techniques; Protein Binding; Serum | 1987 |
Inflammatory disease and the role of Voltaren (diclofenac sodium). Proceedings of a symposium, May 14-15, 1985, Tahiti.
Topics: Animals; Arthritis; Diclofenac; Humans; Inflammation | 1986 |
Differential diagnosis of acute dactylitis psoriatica.
Topics: Aged; Anti-Inflammatory Agents; Arthritis; Diagnosis, Differential; Diclofenac; Female; Fingers; Hum | 1986 |
Adult onset Still's disease in the elderly: a report of two cases.
Topics: Aged; Arthritis; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Diagnosis, Differentia | 1985 |