diclofenac has been researched along with Angiogenesis, Pathologic in 12 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Angiostasis and vascular regression in chronic granulomatous inflammation was assessed in mice induced with diclofenac in combination with hyaluronan." | 7.69 | Angiostasis and vascular regression in chronic granulomatous inflammation induced by diclofenac in combination with hyaluronan in mice. ( Alam, CA; Seed, MP; Willoughby, DA, 1995) |
| " TL-118, a novel drug combination has been recently developed to inhibit tumor angiogenesis." | 5.40 | TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model--evaluation by MRI. ( Abramovitch, R; Corchia, N; Dery, E; Fried, I; Gross, E; Komar-Stossel, C; Meir, K, 2014) |
| "Angiostasis and vascular regression in chronic granulomatous inflammation was assessed in mice induced with diclofenac in combination with hyaluronan." | 3.69 | Angiostasis and vascular regression in chronic granulomatous inflammation induced by diclofenac in combination with hyaluronan in mice. ( Alam, CA; Seed, MP; Willoughby, DA, 1995) |
| "The growth rate (studied by mean tumor dry weight) and vascularization (studied by microangiography) of two transplantable rat tumors, a 20-methylcholanthrene-induced fibrosarcoma and a hepatoma, were significantly reduced by three prostaglandin synthesis inhibitors, indomethacin, diclofenac-sodium and aspirin, irrespective of whether the drugs were administered early or late during tumor growth." | 3.66 | Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat. ( Peterson, HI, 1983) |
| " TL-118, a novel drug combination has been recently developed to inhibit tumor angiogenesis." | 1.40 | TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model--evaluation by MRI. ( Abramovitch, R; Corchia, N; Dery, E; Fried, I; Gross, E; Komar-Stossel, C; Meir, K, 2014) |
| "We present a first description of a pancreatic cancer patient treated with standard chemotherapy and TL-118, an anti-angiogenic combination of 4 drugs that target non-overlapping aspects of the angiogenic process (Provided by Tiltan Pharma Ltd for compassionate use)." | 1.39 | TL-118-anti-angiogenic treatment in pancreatic cancer: a case report. ( Appelbaum, L; Breuer, S; Hubert, A; Maimon, O; Peretz, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gungor, H | 2 |
| Ilhan, N | 2 |
| Eroksuz, H | 2 |
| Breuer, S | 1 |
| Maimon, O | 1 |
| Appelbaum, L | 1 |
| Peretz, T | 1 |
| Hubert, A | 1 |
| Komar-Stossel, C | 1 |
| Gross, E | 1 |
| Dery, E | 1 |
| Corchia, N | 1 |
| Meir, K | 1 |
| Fried, I | 1 |
| Abramovitch, R | 1 |
| Gul, HF | 1 |
| Ghanghas, P | 1 |
| Jain, S | 1 |
| Rana, C | 1 |
| Sanyal, SN | 1 |
| Mayorek, N | 1 |
| Naftali-Shani, N | 1 |
| Grunewald, M | 1 |
| Reim, M | 1 |
| von Kiether, R | 1 |
| Oglodek, C | 1 |
| Schaffelt, F | 1 |
| Thüne, G | 1 |
| Peterson, HI | 1 |
| Alam, CA | 3 |
| Seed, MP | 4 |
| Willoughby, DA | 4 |
| Freemantle, C | 1 |
| Brown, JR | 3 |
| Freemantle, CN | 2 |
| Papworth, JL | 2 |
| Colville-Nash, PR | 2 |
| Willis, D | 1 |
| Somerville, KW | 2 |
| Asculai, S | 1 |
1 review available for diclofenac and Angiogenesis, Pathologic
| Article | Year |
|---|---|
The modulation of granulomatous tissue and tumour angiogenesis by diclofenac in combination with hyaluronan (HYAL EX-0001).
Topics: Animals; Diclofenac; Drug Delivery Systems; Granuloma; Humans; Hyaluronic Acid; Neoplasms; Neovascul | 1995 |
11 other studies available for diclofenac and Angiogenesis, Pathologic
| Article | Year |
|---|---|
The effectiveness of cyclooxygenase-2 inhibitors and evaluation of angiogenesis in the model of experimental colorectal cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 2 Inhibit | 2018 |
TL-118-anti-angiogenic treatment in pancreatic cancer: a case report.
Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Cyclophos | 2013 |
TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model--evaluation by MRI.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Prolifera | 2014 |
Expression of Endoglin and Vascular Endothelial Growth Factor as Prognostic Markers in Experimental Colorectal Cancer.
Topics: Adenocarcinoma; Animals; Biomarkers, Tumor; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 2 Inhibi | 2016 |
Chemoprevention of Colon Cancer through Inhibition of Angiogenesis and Induction of Apoptosis by Nonsteroidal Anti-Inflammatory Drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Celecoxib; Col | 2016 |
Diclofenac inhibits tumor growth in a murine model of pancreatic cancer by modulation of VEGF levels and arginase activity.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Arginase; Cell Proliferation; Di | 2010 |
[Effect of inhibitors of prostaglandin synthesis on the eye].
Topics: Animals; Burns, Chemical; Diclofenac; Eye; Eye Burns; Eye Diseases; Humans; Indomethacin; Inflammati | 1983 |
Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat.
Topics: Animals; Aspirin; Diclofenac; Fibrosarcoma; Indomethacin; Liver Neoplasms, Experimental; Neoplasm Tr | 1983 |
Angiostasis and vascular regression in chronic granulomatous inflammation induced by diclofenac in combination with hyaluronan in mice.
Topics: Administration, Topical; Animals; Blood Vessels; Chronic Disease; Diclofenac; Drug Combinations; Fem | 1995 |
The inhibition of colon-26 adenocarcinoma development and angiogenesis by topical diclofenac in 2.5% hyaluronan.
Topics: Adenocarcinoma; Administration, Topical; Animals; Apoptosis; Cell Survival; Colonic Neoplasms; Cyclo | 1997 |
Apoptosis induction and inhibition of colon-26 tumour growth and angiogenesis: findings on COX-1 and COX-2 inhibitors in vitro & in vivo and topical diclofenac in hyaluronan.
Topics: Administration, Topical; Animals; Apoptosis; Aspirin; Cell Division; Cell Survival; Colonic Neoplasm | 1997 |