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diclofenac and Anemia, Hemolytic, Autoimmune

diclofenac has been researched along with Anemia, Hemolytic, Autoimmune in 14 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Anemia, Hemolytic, Autoimmune: Acquired hemolytic anemia due to the presence of AUTOANTIBODIES which agglutinate or lyse the patient's own RED BLOOD CELLS.

Research Excerpts

ExcerptRelevanceReference
"Severe immune haemolytic anaemia and thrombocytopenia developed in a 71-year-old female within 10 d of starting diclofenac (Voltarol) therapy."7.67Severe reversible autoimmune haemolytic anaemia and thrombocytopenia associated with diclofenac therapy. ( Hershko, C; Kramer, MR; Levene, C, 1986)
"Diclofenac has been implicated in many cases of life-threatening immune hemolytic anemia (IHA)."5.33Misdiagnosis in patients with diclofenac-induced hemolysis: new cases and a concise review. ( Ahrens, N; Genth, R; Kiesewetter, H; Salama, A, 2006)
"We report the case of a 72-year-old woman who developed fatal immune hemolytic anemia with multisystem organ failure and shock caused by diclofenac-dependent red blood cell autoantibodies."3.71Fatal acute diclofenac-induced immune hemolytic anemia. ( Jörres, A; Jürgensen, JS; Seltsam, A, 2001)
"Severe immune haemolytic anaemia and thrombocytopenia developed in a 71-year-old female within 10 d of starting diclofenac (Voltarol) therapy."3.67Severe reversible autoimmune haemolytic anaemia and thrombocytopenia associated with diclofenac therapy. ( Hershko, C; Kramer, MR; Levene, C, 1986)
"Diclofenac has been implicated in many cases of life-threatening immune hemolytic anemia (IHA)."1.33Misdiagnosis in patients with diclofenac-induced hemolysis: new cases and a concise review. ( Ahrens, N; Genth, R; Kiesewetter, H; Salama, A, 2006)
"Diclofenac (DCF) is a widely used nonsteroidal anti-inflammatory drug implicated as a cause of immune hemolytic anemia."1.32Diclofenac-induced antibodies against red blood cells are heterogeneous and recognize different epitopes. ( Bein, G; Kroll, H; Röder, L; Sachs, UJ; Santoso, S; Smart, E, 2004)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's6 (42.86)18.2507
2000's4 (28.57)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garbe, E2
Andersohn, F1
Bronder, E1
Klimpel, A1
Thomae, M1
Schrezenmeier, H1
Hildebrandt, M1
Späth-Schwalbe, E1
Grüneisen, A1
Mayer, B1
Salama, A4
Kurtal, H1
Fuchs, T1
Puellmann, K1
Schneider, S1
Kruth, J1
Schulze, TJ1
Neumaier, M1
Beham, AW1
Kaminski, WE1
Ahrens, N2
Schewior, L1
Kiesewetter, H2
Sachs, UJ1
Santoso, S1
Röder, L1
Smart, E1
Bein, G1
Kroll, H2
Genth, R1
MacKay, AD1
Mehta, A1
Berghöfer, H1
Ernst-Schlegel, M1
Mueller-Eckhardt, C1
Yanaihara, H1
Nakazono, M1
Tsunoda, S1
de Quirós, JF1
Pinto, V1
Hevia, S1
Vigón, R1
Bougie, D1
Johnson, ST1
Weitekamp, LA1
Aster, RH1
Jürgensen, JS1
Seltsam, A1
Jörres, A1
Heuft, HG1
Postels, H1
Hoppe, I1
Weisbach, V1
Zeiler, T1
Zingsem, J1
Eckstein, R1
Kramer, MR1
Levene, C1
Hershko, C1
Mitsutani, S1

Other Studies

14 other studies available for diclofenac and Anemia, Hemolytic, Autoimmune

ArticleYear
Drug induced immune haemolytic anaemia in the Berlin Case-Control Surveillance Study.
    British journal of haematology, 2011, Volume: 154, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; An

2011
An autoimmune double attack.
    Lancet (London, England), 2012, Apr-07, Volume: 379, Issue:9823

    Topics: Acute Kidney Injury; Aged; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents, Non-Steroidal; A

2012
Massive haemolysis after intramuscular diclofenac in a patient who apparently tolerated oral medication.
    Vox sanguinis, 2004, Volume: 86, Issue:1

    Topics: Administration, Oral; Aged; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Antibodies; Diagnosis,

2004
Diclofenac-induced antibodies against red blood cells are heterogeneous and recognize different epitopes.
    Transfusion, 2004, Volume: 44, Issue:8

    Topics: Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Diclofenac; Epit

2004
Misdiagnosis in patients with diclofenac-induced hemolysis: new cases and a concise review.
    American journal of hematology, 2006, Volume: 81, Issue:2

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antibodies; Coombs Test

2006
Autoimmune haemolytic anaemia associated with ciprofloxacin.
    Clinical and laboratory haematology, 1995, Volume: 17, Issue:1

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Bacteremia; Ciprofloxacin; Diclofenac; Female; Humans; Osteomye

1995
[Detection of drug-induced antibodies to erythrocytes in the gel test].
    Beitrage zur Infusionstherapie = Contributions to infusion therapy, 1993, Volume: 31

    Topics: Anemia, Hemolytic, Autoimmune; Autoantibodies; Carbimazole; Catechin; Cefotaxime; Coombs Test; Diclo

1993
[A case of drug-induced immune hemolytic anemia during alpha-interferon therapy for renal cell carcinoma].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1996, Volume: 87, Issue:3

    Topics: Anemia, Hemolytic, Autoimmune; Carcinoma, Renal Cell; Diclofenac; Female; Humans; Indomethacin; Inte

1996
Immune complex-mediated haemolytic anaemia and Evans syndrome induced by diclofenac.
    Vox sanguinis, 1997, Volume: 72, Issue:2

    Topics: Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Antibody Complex; Di

1997
Sensitivity to a metabolite of diclofenac as a cause of acute immune hemolytic anemia.
    Blood, 1997, Jul-01, Volume: 90, Issue:1

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents, Non-Steroidal; Autoantibodies; Diclof

1997
Fatal acute diclofenac-induced immune hemolytic anemia.
    Annals of hematology, 2001, Volume: 80, Issue:7

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents, Non-Steroidal; Autoantibodies; Diclof

2001
[Fatal course of immune hemolytic anemia following administration of diclofenac].
    Beitrage zur Infusionstherapie = Contributions to infusion therapy, 1990, Volume: 26

    Topics: Anemia, Hemolytic, Autoimmune; Coombs Test; Diclofenac; Female; Hemoglobinometry; Humans; Injections

1990
Severe reversible autoimmune haemolytic anaemia and thrombocytopenia associated with diclofenac therapy.
    Scandinavian journal of haematology, 1986, Volume: 36, Issue:1

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Autoantibodies; Complement C3; Diclofenac; Erythrocytes; Female

1986
[Appearance of monoclonal gammopathy and auto-immune hemolytic anemia following intake of drugs].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1985, Volume: 48, Issue:3

    Topics: Anemia, Hemolytic, Autoimmune; Diclofenac; Humans; Hypergammaglobulinemia; Immunoglobulin G; Male; M

1985