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diclofenac and Allergy, Drug

diclofenac has been researched along with Allergy, Drug in 51 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate whether an intraoperative bronchospasm is more frequent in sinus surgery than in non-sinus surgery, whether its appearance after application of a non-steroidal anti-inflammatory drug (NSAID) is an indicator of an aspirin intolerance syndrome, and whether its appearance can be interpreted as an aspirin provocation test."7.73[Intraoperative bronchospasm during paranasal sinus surgery -- indicator of aspirin intolerance syndrome?]. ( Blidaru, N; Keck, T; Polzehl, D; Rockemann, M; Rozsasi, A; Santak, B, 2006)
"The features of both these cases are suggestive of delayed hypersensitivity to diclofenac."7.70Delayed hypersensitivity to diclofenac: a report on two cases. ( Artesani, MC; Di Fonso, M; Papa, G; Quaratino, D; Romano, A; Venuti, A, 1998)
"A case of apparent anaphylactic reaction to diclofenac sodium (Voltaren) is reported."7.68Fatal anaphylactic reaction to diclofenac. ( Alkhawajah, AM; Eifawal, M; Mahmoud, SF, 1993)
"Grade 3 severe anaphylactic reactions occurred in seven cases of nine."5.40Anaphylaxis to diclofenac: nine cases reported to the Allergy Vigilance Network in France. ( Beaudouin, E; Dron-Gonzalvez, M; Metz-Favre, C; Moneret-Vautrin, DA; Picaud, J; Pirson, F; Renaudin, JM, 2014)
"Diclofenac was applied with or without gastric acid suppression, in various doses, alone or covalently coupled to albumin, a protein abundant in gastric juices."5.36Suppression of gastric acid increases the risk of developing immunoglobulin E-mediated drug hypersensitivity: human diclofenac sensitization and a murine sensitization model. ( Gruber, S; Jensen-Jarolim, E; Kinaciyan, T; Pali-Schöll, I; Riemer, AB; Untersmayr, E, 2010)
" As for SCARs, associations of HLA-B*15:02 or HLA-A*31:01 and HLA-B*58:01 have been revealed for carbamazepine- and allopurinol-related Stevens-Johnson syndrome and toxic epidermal neclolysis, respectively."4.89Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury. ( Kaniwa, N; Saito, Y, 2013)
"The aim of this study was to evaluate whether an intraoperative bronchospasm is more frequent in sinus surgery than in non-sinus surgery, whether its appearance after application of a non-steroidal anti-inflammatory drug (NSAID) is an indicator of an aspirin intolerance syndrome, and whether its appearance can be interpreted as an aspirin provocation test."3.73[Intraoperative bronchospasm during paranasal sinus surgery -- indicator of aspirin intolerance syndrome?]. ( Blidaru, N; Keck, T; Polzehl, D; Rockemann, M; Rozsasi, A; Santak, B, 2006)
"The features of both these cases are suggestive of delayed hypersensitivity to diclofenac."3.70Delayed hypersensitivity to diclofenac: a report on two cases. ( Artesani, MC; Di Fonso, M; Papa, G; Quaratino, D; Romano, A; Venuti, A, 1998)
" Both patients exhibited anaphylactic manifestations, such as general rash and urticaria, along with angina pectoris with electrocardiographic ST-segment elevations after suppository administration of diclofenac sodium or indomethacin, the most commonly used NSAIDs."3.69Vasospastic angina induced by nonsteroidal anti-inflammatory drugs. ( Eguchi, H; Haramaki, N; Hashino, T; Ichiki, K; Ikeda, H; Imaizumi, T; Kai, H; Katoh, A; Mori, E; Ueno, T; Ueyama, T, 1997)
"A case of apparent anaphylactic reaction to diclofenac sodium (Voltaren) is reported."3.68Fatal anaphylactic reaction to diclofenac. ( Alkhawajah, AM; Eifawal, M; Mahmoud, SF, 1993)
"Ketorolac is approved for the relief of postoperative pain but concerns have been raised over a possible risk of serious adverse effects and death."2.70Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery. ( Abdalla, M; Bianchi, PG; Bonnet, F; Camu, F; Ebrahim, S; Escolar, G; Forrest, JB; Greer, IA; Heitlinger, E; Jage, J; Kehlet, H; Langman, MJ; Pocock, S; Samama, MM; Velo, G, 2002)
"However, some patients may develop acute liver failure and successful orthotopic liver transplantation may be undertaken in such patients."2.42Hepatocellular damage from non-steroidal anti-inflammatory drugs. ( Dargan, PI; Jones, AL; O'Connor, N, 2003)
"Grade 3 severe anaphylactic reactions occurred in seven cases of nine."1.40Anaphylaxis to diclofenac: nine cases reported to the Allergy Vigilance Network in France. ( Beaudouin, E; Dron-Gonzalvez, M; Metz-Favre, C; Moneret-Vautrin, DA; Picaud, J; Pirson, F; Renaudin, JM, 2014)
"Immune-mediated drug hypersensitivity is a particularly concerning health-safety issue among clinicians given its unpredictability and potentially life-threatening effects, especially with exposure to intravenous drugs."1.38An intravenous exposure mouse model for prediction of potential drug-sensitization using reporter antigens popliteal lymph node assay. ( Fan, X; Gong, W; Jin, Y; Li, X; Lin, M; Sun, W; Wang, Y, 2012)
"Diclofenac was applied with or without gastric acid suppression, in various doses, alone or covalently coupled to albumin, a protein abundant in gastric juices."1.36Suppression of gastric acid increases the risk of developing immunoglobulin E-mediated drug hypersensitivity: human diclofenac sensitization and a murine sensitization model. ( Gruber, S; Jensen-Jarolim, E; Kinaciyan, T; Pali-Schöll, I; Riemer, AB; Untersmayr, E, 2010)
"The patient also presented an immediate hypersensitivity reaction after taking diclofenac."1.35Systemic dermatitis due to tetrazepam. ( Laguna-Martínez, JJ; Reaño-Martos, M; Rojo-Andrés, E; Sánchez-Morillas, L; Ubeda, PG, 2008)
"Anaphylaxis, acute coronary syndrome and pulmonary embolism are conditions commonly seen in the acute medical setting which can be difficult to diagnose."1.34Anaphylactic shock: the great mimic. ( Birns, J; Ibrahim, MA; Yong, PF, 2007)
"The diclofenac therapy was discontinued."1.32[Pulmonary infiltrates with blood eosinophilia in a 62-year-old patient]. ( Geiger, D; Häussinger, K; Kohlhäufl, M; Morresi-Hauf, A; Raith, H; Weber, N, 2003)
"Diclofenac was administered to rats by gastric gavage."1.30Immunochemical detection and identification of protein adducts of diclofenac in the small intestine of rats: possible role in allergic reactions. ( Graf, ML; Lustberg, LR; Martin, BM; Pohl, LR; Ware, JA, 1998)
"Several side effects of drugs observed in an office of a general practitioner are described."1.28[The family physician and drug side-effects. Observations from general practice--conclusions for general practice]. ( Stahl, H, 1989)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19904 (7.84)18.7374
1990's10 (19.61)18.2507
2000's27 (52.94)29.6817
2010's10 (19.61)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaniwa, N1
Saito, Y1
Picaud, J1
Beaudouin, E1
Renaudin, JM1
Pirson, F1
Metz-Favre, C1
Dron-Gonzalvez, M1
Moneret-Vautrin, DA1
Kwast, L2
Fiechter, D2
Kruijssen, L2
Bleumink, R2
Ludwig, I2
Bol-Schoenmakers, M1
Smit, J1
Pieters, R2
Aida, T1
Boon, L1
Sánchez-Morillas, L1
Laguna-Martínez, JJ1
Reaño-Martos, M1
Rojo-Andrés, E1
Ubeda, PG1
Bavbek, S1
Ikincioğullari, A1
Dursun, AB1
Guloğlu, D1
Arikan, M1
Elhan, AH1
Misirligil, Z1
Merk, HF1
Riemer, AB1
Gruber, S1
Pali-Schöll, I1
Kinaciyan, T1
Untersmayr, E1
Jensen-Jarolim, E1
De Weck, AL2
Sanz, ML2
Gamboa, PM1
Aberer, W3
Blanca, M1
Correia, S1
Erdman, S1
Jermann, JM1
Kanny, G1
Kowalski, M1
Mayorga, L1
Medrala, W1
Merk, A1
Sturm, GJ1
Sainte-Laudy, J1
Schneider, MS1
Sczczeklik, A1
Weber, JM1
Wedi, A1
Pickard, C1
Sampson, AP1
Harrer, A2
Lang, R2
Grims, R2
Braitsch, M1
Hawranek, T2
Vogel, L1
Schmid, W1
Ferreira, F1
Himly, M2
Lin, M1
Sun, W1
Wang, Y2
Li, X1
Jin, Y1
Gong, W1
Fan, X1
Steiner, M1
Schneider, M1
Ferreira, T1
Olze, H1
Lau, S1
Förster, U1
Gutting, BW1
Bouzahzah, F1
Kong, PL1
Updyke, LW1
Amacher, DE1
Craft, J1
Blanco, VM1
Möller, I1
Catalán, F1
Casares, G1
O'Connor, N1
Dargan, PI1
Jones, AL1
Jonker, MJ1
Bruynzeel, DP1
Kohlhäufl, M1
Weber, N1
Morresi-Hauf, A1
Geiger, D1
Raith, H1
Häussinger, K1
Gamboa, P1
Caballero, MR1
Urrutia, I1
Antépara, I1
Esparza, R1
Buylaert, MA1
Schifferli, JA1
Schleinitz, N1
Veit, V1
Coso, D1
Aurran, T1
Berbis, P1
Harle, JR1
Bajaj, DR1
Qureshi, AA1
Rojas-Hijazo, B1
Garcés, MM1
Ferrer, L1
Lezaun, A1
Colás, C1
Wyplosz, B1
Vautier, S1
Lillo-Le Louët, A1
Capron, L1
Rozsasi, A1
Blidaru, N1
Rockemann, M1
Santak, B1
Polzehl, D1
Keck, T1
Komericki, P1
Arbab, E1
Kränke, B1
Asero, R1
Malbrán, A1
Yeyati, E1
Rey, GL1
Galassi, N1
Yong, PF1
Birns, J1
Ibrahim, MA1
Akyol-Salman, I1
Leçe-Sertöz, D1
Baykal, O1
Bonafé, JL1
Mazières, B1
Bouteiller, G1
Healy, CM1
Thornhill, MH1
Gills, JP1
Alkhawajah, AM1
Eifawal, M1
Mahmoud, SF1
Mori, E1
Ikeda, H1
Ueno, T1
Kai, H1
Haramaki, N1
Hashino, T1
Ichiki, K1
Katoh, A1
Eguchi, H1
Ueyama, T1
Imaizumi, T1
Ohana, M1
Hajiro, K1
Takakuwa, H1
Okazaki, K1
Kubota, Y1
Imayama, S1
Toshitani, A1
Miyahara, H1
Tanahashi, T1
Uemura, Y1
Koga, T1
Sugawara, N1
Kurimoto, F1
Hata, K1
Ware, JA1
Graf, ML1
Martin, BM1
Lustberg, LR1
Pohl, LR1
Gala, G1
Blanco, R1
Quirce, S1
Pérez-Camo, I1
Alvarez-Fernández, JA1
Díez-Gómez, ML1
Romano, A1
Quaratino, D1
Papa, G1
Di Fonso, M1
Artesani, MC1
Venuti, A1
Enrique, E3
García-Ortega, P1
Gaig, P1
San Miguel, MM1
Cisteró-Bahima, A1
Alonso, R2
Bravo, P1
Fenollosa, A1
Torre, I1
del Pozo, MD1
Lobera, T1
Blasco, A1
Cisteró, A1
Gómez, A1
Florido, JF1
Quiralte, J1
Martín, AE1
Sáenz de San Pedro, B1
Abo, M1
Fujimura, M1
Forrest, JB1
Camu, F1
Greer, IA1
Kehlet, H1
Abdalla, M1
Bonnet, F1
Ebrahim, S1
Escolar, G1
Jage, J1
Pocock, S1
Velo, G1
Langman, MJ1
Bianchi, PG1
Samama, MM1
Heitlinger, E1
Szczeklik, A1
Gryglewski, RJ1
Czerniawska-Mysik, G1
Pieton, R1
Stahl, H1
Schlegel, SI1
Paulus, HE1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Perioperative Usage of Ketorolac on Postoperative Pain Reduction in Pediatric Patients With Adenotonsillectom[NCT05074056]Phase 4200 participants (Anticipated)Interventional2022-02-08Recruiting
Opioid-Free Versus Transitional Anesthetic With Opioids From Tonsillectomy[NCT04528173]Phase 4550 participants (Anticipated)Interventional2020-07-22Recruiting
Acute Kidney Injury and Nonsteroidal Anti-inflammatory Drugs in Patients Undergoing High-risk Abdominal or Thoracic Surgery[NCT02553174]50 participants (Actual)Observational2016-06-01Terminated (stopped due to unable to recruit sufficient patients to satisfy study protocols)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for diclofenac and Allergy, Drug

ArticleYear
Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury.
    Journal of human genetics, 2013, Volume: 58, Issue:6

    Topics: Alleles; Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Azetidines; Benzylamines; Carba

2013
Drug skin metabolites and allergic drug reactions.
    Current opinion in allergy and clinical immunology, 2009, Volume: 9, Issue:4

    Topics: Animals; Anticonvulsants; Antigen Presentation; Cytochrome P-450 Enzyme System; Dermatitis, Allergic

2009
Hepatocellular damage from non-steroidal anti-inflammatory drugs.
    QJM : monthly journal of the Association of Physicians, 2003, Volume: 96, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Injury; D

2003
Non-steroidal and analgesic therapy in the elderly.
    Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1

    Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Cen

1986

Trials

5 trials available for diclofenac and Allergy, Drug

ArticleYear
Upregulation of CD63 or CD203c alone or in combination is not sensitive in the diagnosis of nonsteroidal anti-inflammatory drug intolerance.
    International archives of allergy and immunology, 2009, Volume: 150, Issue:3

    Topics: Administration, Oral; Adult; Antigens, CD; Aspirin; Basophil Degranulation Test; Basophils; Biomarke

2009
Nonsteroidal anti-inflammatory drug hypersensitivity syndrome. A multicenter study. I. Clinical findings and in vitro diagnosis.
    Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Diclofenac; Dr

2009
Topical pranoprofen 0.1% is as effective anti-inflammatory and analgesic agent as diclofenac sodium 0.1% after strabismus surgery.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Ch

2007
Diclofenac-induced fever.
    Allergy, 2000, Volume: 55, Issue:4

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Chlorpheniramine; Diclofenac; Drug Hypers

2000
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
    British journal of anaesthesia, 2002, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico

2002

Other Studies

42 other studies available for diclofenac and Allergy, Drug

ArticleYear
Anaphylaxis to diclofenac: nine cases reported to the Allergy Vigilance Network in France.
    Allergy, 2014, Volume: 69, Issue:10

    Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Hypersensitivity; Femal

2014
Oral exposure to immunostimulating drugs results in early changes in innate immune parameters in the spleen.
    Journal of immunotoxicology, 2016, Volume: 13, Issue:4

    Topics: Acetaminophen; Adaptive Immunity; Administration, Oral; Animals; Carbamazepine; Cells, Cultured; Dic

2016
Immune responses induced by diclofenac or carbamazepine in an oral exposure model using TNP-Ficoll as reporter antigen.
    Journal of immunotoxicology, 2016, Volume: 13, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Carbamazepine; Dic

2016
Systemic dermatitis due to tetrazepam.
    Journal of investigational allergology & clinical immunology, 2008, Volume: 18, Issue:5

    Topics: Administration, Oral; Benzodiazepines; Contracture; Dermatitis, Contact; Diclofenac; Drug Hypersensi

2008
Suppression of gastric acid increases the risk of developing immunoglobulin E-mediated drug hypersensitivity: human diclofenac sensitization and a murine sensitization model.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2010, Volume: 40, Issue:3

    Topics: Animals; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antigen-Antibody Reactions;

2010
Does gastric acid suppression increase the risk of drug allergies?
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2010, Volume: 40, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Hypersensitivity; Gastric Acid; H

2010
Diclofenac hypersensitivity: antibody responses to the parent drug and relevant metabolites.
    PloS one, 2010, Oct-28, Volume: 5, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Basophils; Diclofenac; Drug Hypersensi

2010
An intravenous exposure mouse model for prediction of potential drug-sensitization using reporter antigens popliteal lymph node assay.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:6

    Topics: Adjuvants, Immunologic; Allergens; Animals; Antigen-Antibody Reactions; Antigens; Cell Proliferation

2012
Basophil activation test for investigation of IgE-mediated mechanisms in drug hypersensitivity.
    Journal of visualized experiments : JoVE, 2011, Sep-16, Issue:55

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Basophils; Chromatography, Gel; Chromatography,

2011
Samter's triad and eicosanoid imbalance in children with recurrent nasal polyps.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2012, Volume: 23, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Child; Diclofenac; Drug Hypersensitivit

2012
Oxazolone and diclofenac-induced popliteal lymph node assay reactions are attenuated in mice orally pretreated with the respective compound: potential role for the induction of regulatory mechanisms following enteric administration.
    Toxicology and applied pharmacology, 2003, Jun-01, Volume: 189, Issue:2

    Topics: Adjuvants, Immunologic; Administration, Oral; Adoptive Transfer; Animals; Anti-Inflammatory Agents,

2003
[Acute myocardial infarction during a diclofenac-associated anaphylactic reaction].
    Medicina clinica, 2003, Sep-06, Volume: 121, Issue:7

    Topics: Anaphylaxis; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dr

2003
Anaphylactic reaction elicited by patch testing with diclofenac.
    Contact dermatitis, 2003, Volume: 49, Issue:2

    Topics: Adult; Anaphylaxis; Diclofenac; Drug Hypersensitivity; Female; Humans; Patch Tests

2003
[Pulmonary infiltrates with blood eosinophilia in a 62-year-old patient].
    Der Internist, 2003, Volume: 44, Issue:8

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cough; Diclofenac

2003
The flow-cytometric determination of basophil activation induced by aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is useful for in vitro diagnosis of the NSAID hypersensitivity syndrome.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:9

    Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Basophil Degra

2004
[Acute renal failure--"a well meant present from a friend"].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:12

    Topics: Acute Kidney Injury; Administration, Cutaneous; Administration, Oral; Aged; Anti-Inflammatory Agents

2004
Drug-induced eosinophilia and systemic symptoms: hypersensitivity or peripheral T-cell lymphoma?
    Archives of dermatology, 2005, Volume: 141, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Cyclophosphamide; Diagnosis,

2005
Embolia cutis medicamentosa.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2005, Volume: 15, Issue:3

    Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Diclofenac; Drug Hypersensitivity; Female; Fo

2005
Anaphylactic reaction after aceclofenac intake.
    Allergy, 2006, Volume: 61, Issue:4

    Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Hypersensitivity; Human

2006
Tolerance of diclofenac after hypersensitivity to celecoxib and to nabumetone.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:4

    Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inh

2006
[Intraoperative bronchospasm during paranasal sinus surgery -- indicator of aspirin intolerance syndrome?].
    Laryngo- rhino- otologie, 2006, Volume: 85, Issue:6

    Topics: Acetaminophen; Adult; Aged; Algorithms; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal

2006
Tryptase as severity marker in drug provocation tests.
    International archives of allergy and immunology, 2006, Volume: 140, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aspirin; Diclofenac; Drug Hypersensitivity; Female; Humans; Lidoca

2006
Oral anticoagulants may prevent NSAID-induced urticaria.
    Clinical and experimental dermatology, 2006, Volume: 31, Issue:4

    Topics: Acenocoumarol; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Diclofenac; Drug Hypersensit

2006
Diclofenac induces basophil degranulation without increasing CD63 expression in sensitive patients.
    Clinical and experimental immunology, 2007, Volume: 147, Issue:1

    Topics: Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Basophil Degranulation Te

2007
Anaphylactic shock: the great mimic.
    Southern medical journal, 2007, Volume: 100, Issue:3

    Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Coronary Disease; Diagnosis, Differenti

2007
[Gougerot's trisymptom complex induced by anti-inflammatory agents. Role of diclofenac?].
    Annales de dermatologie et de venereologie, 1982, Volume: 109, Issue:3

    Topics: Anti-Inflammatory Agents; Diclofenac; Drug Hypersensitivity; Humans; Male; Middle Aged; Phenylacetat

1982
An association between recurrent oro-genital ulceration and non-steroidal anti-inflammatory drugs.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1995, Volume: 24, Issue:1

    Topics: Diclofenac; Drug Hypersensitivity; Female; Flurbiprofen; Genital Diseases, Female; Humans; Middle Ag

1995
Voltaren associated with medication keratitis.
    Journal of cataract and refractive surgery, 1994, Volume: 20, Issue:1

    Topics: Diclofenac; Drug Hypersensitivity; Humans; Keratitis; Macular Edema

1994
Fatal anaphylactic reaction to diclofenac.
    Forensic science international, 1993, Volume: 60, Issue:1-2

    Topics: Anaphylaxis; Diclofenac; Drug Hypersensitivity; Humans; Low Back Pain; Male; Middle Aged

1993
Vasospastic angina induced by nonsteroidal anti-inflammatory drugs.
    Clinical cardiology, 1997, Volume: 20, Issue:7

    Topics: Aged; Angina Pectoris; Anti-Inflammatory Agents, Non-Steroidal; Coronary Angiography; Coronary Vasos

1997
Recovery from diclofenac-induced hypersensitive fulminant hepatitis and prostaglandins.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:10

    Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Diclof

1997
Sulfidoleukotriene release test (CAST) in hypersensitivity to nonsteroidal anti-inflammatory drugs.
    International archives of allergy and immunology, 1997, Volume: 114, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Drug Hypersensitivity; Fe

1997
Immunochemical detection and identification of protein adducts of diclofenac in the small intestine of rats: possible role in allergic reactions.
    Chemical research in toxicology, 1998, Volume: 11, Issue:3

    Topics: Acetaminophen; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrier Prote

1998
Diclofenac-induced urticaria with aspirin tolerance.
    Allergy, 1998, Volume: 53, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Drug Hypersensitivity; Female; Humans;

1998
Delayed hypersensitivity to diclofenac: a report on two cases.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 81, Issue:4

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Hypersensitivity; Female; Humans; Hy

1998
Failure of montelukast to prevent anaphylaxis to diclofenac.
    Allergy, 1999, Volume: 54, Issue:5

    Topics: Acetates; Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclopropanes; Diclo

1999
Selective hypersensitivity to diclofenac.
    Allergy, 2000, Volume: 55, Issue:4

    Topics: Adult; Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Hypersensitivity

2000
Positive patch test to diclofenac in Stevens-Johnson syndrome.
    Contact dermatitis, 2000, Volume: 42, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Hypersensitivity; Humans; Male; Patc

2000
Allergic contact dermatitis due to indomethacin and diclofenac.
    Contact dermatitis, 2000, Volume: 43, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cross Reactions; Dermatitis, Allergic Contact; Diagnosis, D

2000
Tacholiquine inhalation and aspirin-induced asthma.
    Chest, 2001, Volume: 119, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Diclofenac; Drug Hypersensitivity; E

2001
Asthmatic attacks induced in aspirin-sensitive patients by diclofenac and naproxen.
    British medical journal, 1977, Jul-23, Volume: 2, Issue:6081

    Topics: Adult; Aspirin; Asthma; Cyclooxygenase Inhibitors; Diclofenac; Drug Hypersensitivity; Female; Humans

1977
[The family physician and drug side-effects. Observations from general practice--conclusions for general practice].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1989, Aug-15, Volume: 78, Issue:33

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anaphylaxis; Anti-Inflammatory Agents, Non-Ste

1989