diclofenac has been researched along with Active Hyperemia in 8 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Side effect incidence and patient and investigator opinions were also recorded." | 2.69 | Tolerability and safety of 0.1% diclofenac plus 0.3% tobramycin fixed-dose ophthalmic solution: a randomized, comparative, controlled study in healthy volunteers. ( Andreu, D; Costa, J; Martínez, M; Notivol, R; Salvá, P, 1999) |
| "Ibuprofen was the most efficient agent, inhibiting the total reactive hyperemia by more than 70%, and naproxen was least active, producing about 35% inhibition." | 2.65 | Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm. ( Carlsson, I; Wennmalm, A, 1983) |
| "Bradykinin-induced increase in 6-ketoprostaglandin F1 alpha production was greater in coronary arteries taken from L-NNA-treated dogs (+ 179 +/- 41 pg/mm2) than from control dogs (+ 66 +/- 18 pg/mm2) (P < ." | 2.39 | Coronary and systemic hemodynamic effects of sustained inhibition of nitric oxide synthesis in conscious dogs. Evidence for cross talk between nitric oxide and cyclooxygenase in coronary vessels. ( Béa, ML; Berdeaux, A; Ghaleh, B; Giudicelli, JF; Puybasset, L, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kocak, I | 1 |
| Aydin, A | 1 |
| Sahbaz, I | 1 |
| Kaya, F | 1 |
| Baybora, H | 1 |
| Fromy, B | 1 |
| Lingueglia, E | 1 |
| Sigaudo-Roussel, D | 1 |
| Saumet, JL | 1 |
| Lazdunski, M | 1 |
| Carlsson, I | 1 |
| Wennmalm, A | 1 |
| Puybasset, L | 1 |
| Béa, ML | 1 |
| Ghaleh, B | 1 |
| Giudicelli, JF | 2 |
| Berdeaux, A | 2 |
| Andrieu, S | 1 |
| Lebret, M | 1 |
| Maclouf, J | 1 |
| Bévérelli, F | 1 |
| Salvá, P | 1 |
| Costa, J | 1 |
| Andreu, D | 1 |
| Notivol, R | 1 |
| Martínez, M | 1 |
| Hersh, PS | 1 |
| Rice, BA | 1 |
| Baer, JC | 1 |
| Wells, PA | 1 |
| Lynch, SE | 1 |
| McGuigan, LJ | 1 |
| Foster, CS | 1 |
| Phillis, JW | 1 |
| DeLong, RE | 1 |
| Towner, JK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of the Cutaneous Microcirculation: ASIC Involvement.[NCT01246180] | 20 participants (Actual) | Interventional | 2010-10-31 | Completed | |||
| Cerebral Vasodilator Responses in Sedentary and Exercise Trained Humans[NCT02653638] | Early Phase 1 | 80 participants (Actual) | Interventional | 2016-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for diclofenac and Active Hyperemia
| Article | Year |
|---|---|
Coronary and systemic hemodynamic effects of sustained inhibition of nitric oxide synthesis in conscious dogs. Evidence for cross talk between nitric oxide and cyclooxygenase in coronary vessels.
Topics: Acetylcholine; Animals; Bradykinin; Coronary Circulation; Coronary Vessels; Diclofenac; Dogs; Epopro | 1996 |
2 trials available for diclofenac and Active Hyperemia
| Article | Year |
|---|---|
Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm.
Topics: Adolescent; Adult; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Female; Forearm; Humans; Hyperemi | 1983 |
Tolerability and safety of 0.1% diclofenac plus 0.3% tobramycin fixed-dose ophthalmic solution: a randomized, comparative, controlled study in healthy volunteers.
Topics: Adolescent; Adult; Conjunctiva; Cross-Over Studies; Diclofenac; Double-Blind Method; Drug Combinatio | 1999 |
5 other studies available for diclofenac and Active Hyperemia
| Article | Year |
|---|---|
The management of corneal melt occurring after collagen cross-linking for keratoconus.
Topics: Adult; Conjunctival Diseases; Corneal Edema; Corneal Injuries; Cross-Linking Reagents; Dexamethasone | 2015 |
Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressure ulcers.
Topics: Acid Sensing Ion Channels; Adult; Amiloride; Animals; Calcitonin; Cnidarian Venoms; Diclofenac; Endo | 2012 |
Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bradykinin; Coronary Disease; Coronary Vessels; Cycl | 1999 |
Topical nonsteroidal agents and corneal wound healing.
Topics: Administration, Topical; Analysis of Variance; Animals; Collagen; Cornea; Corneal Edema; Corneal Inj | 1990 |
Indomethacin and ibuprofen enhance anoxia-induced hyperemia in rat brain.
Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Diclofenac; Extracorporeal Circulation; Hypere | 1986 |