diclofenac has been researched along with Abdominal Migraine in 40 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether baseline nausea or prior triptan treatment for migraine impact the effectiveness of diclofenac potassium for oral solution in treating acute migraine." | 9.24 | Post Hoc Subanalysis of Two Randomized, Controlled Phase 3 Trials Evaluating Diclofenac Potassium for Oral Solution: Impact of Migraine-Associated Nausea and Prior Triptan Use on Efficacy. ( Diener, HC; Lipton, RB; Schmidt, P, 2017) |
| "A randomized, controlled, cross-over trial compared single doses of 50 mg diclofenac potassium sachets and tablets with placebo in 328 patients with migraine pain, treating 888 attacks." | 9.12 | Efficacy and tolerability of diclofenac potassium sachets in migraine: a randomized, double-blind, cross-over study in comparison with diclofenac potassium tablets and placebo. ( Diener, HC; Edson, K; Gács, G; Lyczak, P; Montagna, P; Mulder, LJ; Schumann, G; Siegel, J; Zöller, B, 2006) |
| "To determine whether baseline nausea or prior triptan treatment for migraine impact the effectiveness of diclofenac potassium for oral solution in treating acute migraine." | 5.24 | Post Hoc Subanalysis of Two Randomized, Controlled Phase 3 Trials Evaluating Diclofenac Potassium for Oral Solution: Impact of Migraine-Associated Nausea and Prior Triptan Use on Efficacy. ( Diener, HC; Lipton, RB; Schmidt, P, 2017) |
| "This review was designated to evaluate the efficacy of parenteral ketorolac in treating acute migraine headache." | 5.22 | Efficacy of ketorolac in the treatment of acute migraine attack: A systematic review and meta-analysis. ( Abu Bakar, MA; Baharuddin, KA; Norhayati, MN; Nurathirah, MN; Yazid, MB, 2022) |
| "A randomized, controlled, cross-over trial compared single doses of 50 mg diclofenac potassium sachets and tablets with placebo in 328 patients with migraine pain, treating 888 attacks." | 5.12 | Efficacy and tolerability of diclofenac potassium sachets in migraine: a randomized, double-blind, cross-over study in comparison with diclofenac potassium tablets and placebo. ( Diener, HC; Edson, K; Gács, G; Lyczak, P; Montagna, P; Mulder, LJ; Schumann, G; Siegel, J; Zöller, B, 2006) |
| " However, long-term use of NSAIDs is associated with side-effects, mainly involving the gastrointestinal tract." | 3.77 | [Migraine and non-steroidal anti-inflammatory agents]. ( Pradalier, A; Vincent, D, 1992) |
| "In treatment of refractory migraine headache, CAMBIA® may provide similar benefits as IM ketorolac without increasing the risk of treatment failure, major bleeding, or cardiovascular events." | 2.94 | IM ketorolac vs diclofenac potassium powder for oral solution for the acute treatment of severe migraine: a randomized controlled trial. ( Cheng, J; Engel, ER, 2020) |
| "Adult sufferers with an established migraine diagnosis according to the International Classification of Headache Disorders, second edition (ICHD-II), treated one moderate or severe attack with 50 mg diclofenac potassium for oral solution (dissolved in approximately 2 ounces of water; N=343) or matching placebo (N=347)." | 2.75 | Efficacy and tolerability of a new powdered formulation of diclofenac potassium for oral solution for the acute treatment of migraine: results from the International Migraine Pain Assessment Clinical Trial (IMPACT). ( Grosberg, B; Lipton, RB; Pearlman, SH; Quiring, JN; Saper, JR; Singer, RP; Sorrentino, JV, 2010) |
| "5 mg combined with either aceclofenac 100 mg or placebo." | 2.73 | Almotriptan and its combination with aceclofenac for migraine attacks: a study of efficacy and the influence of auto-evaluated brush allodynia. ( De Klippel, N; Giurgea, S; Herroelen, L; Jacquy, J; Louis, P; Monseu, G; Schoenen, J; Vandenheede, M, 2008) |
| "Sumatriptan is a specific migraine treatment which has recently become among the most widely prescribed acute migraine therapies." | 2.69 | Acute treatment of migraine attacks: efficacy and safety of a nonsteroidal anti-inflammatory drug, diclofenac-potassium, in comparison to oral sumatriptan and placebo. The Diclofenac-K/Sumatriptan Migraine Study Group. ( , 1999) |
| "Forty-six patients with acute migraine attacks were treated with intramuscular injection of 75 mg diclofenac sodium, and another group of forty patients with intramuscular injection of paracetamol." | 2.67 | Treatment of acute migraine attack with diclofenac sodium: a double-blind study. ( Chrisikos, N; Fotiadou, A; Karabetsos, A; Karachalios, GN; Kehagioglou, K, 1992) |
| "Diclofenac was significantly more effective than placebo (p less than 0." | 2.67 | Effectiveness of oral diclofenac in the acute treatment of common migraine attacks: a double-blind study versus placebo. ( Bousser, MG; Lasserre, O; Massiou, H; Serrurier, D, 1991) |
| "Migraine is a common, disabling condition and a burden for the individual, health services and society." | 2.49 | Diclofenac with or without an antiemetic for acute migraine headaches in adults. ( Derry, S; Moore, RA; Rabbie, R, 2013) |
| "Migraine is a common, disabling condition and a burden for the individual, health services and society." | 2.48 | Diclofenac with or without an antiemetic for acute migraine headaches in adults. ( Derry, S; Moore, RA; Rabbie, R, 2012) |
| "Migraineurs often do not use acute migraine-specific medications." | 2.46 | Meeting acute migraine treatment needs through novel treatment formulations. ( Silberstein, SD, 2010) |
| "Diclofenac-potassium was developed as an immediate-release tablet with the aim of providing rapid onset of action after oral administration." | 2.40 | Diclofenac-potassium in migraine: a review. ( Goa, KL; McNeely, W, 1999) |
| "These drugs can be categorized into migraine-specific and migraine-non-specific." | 1.72 | 2022 Taiwan Guidelines for Acute Treatment of Migraine. ( Lau, CI; Wang, YF, 2022) |
| "Among migraine patients, 80% had used NSAIDs in the past year." | 1.46 | Use of Nonsteroidal Anti-Inflammatory Drugs for Symptomatic Treatment of Episodic Headache. ( Affaitati, G; Cipollone, F; Costantini, R; Giamberardino, MA; Lapenna, D; Lopopolo, M; Martelletti, P; Massimini, F; Tana, C, 2017) |
| " A microemulsion-based technology has various advantages over other technically complex dosage forms." | 1.40 | Duel-acting subcutaneous microemulsion formulation for improved migraine treatment with zolmitriptan and diclofenac: formulation and in vitro-in vivo characterization. ( Christie, M; Dubey, R; Martini, LG, 2014) |
| "Of the patients with migraine, 83." | 1.30 | [Headache treatment in an emergency unit of the city of Ribeirão Preto, Brazil]. ( Bigal, ME; Bordini, CA; Speciali, JG, 1999) |
| "In case of migraine associated with dysmenorrhoea and/or premenstrual tension the management with triphasic hormone proved to be of therapeutic value." | 1.28 | The relation between atypical migraine and multiphasic oral contraceptives. ( Dienes, L; Szigethy, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.50) | 18.7374 |
| 1990's | 10 (25.00) | 18.2507 |
| 2000's | 11 (27.50) | 29.6817 |
| 2010's | 14 (35.00) | 24.3611 |
| 2020's | 4 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nurathirah, MN | 1 |
| Yazid, MB | 1 |
| Norhayati, MN | 1 |
| Baharuddin, KA | 1 |
| Abu Bakar, MA | 1 |
| Geppetti, P | 1 |
| De Cesaris, F | 1 |
| Benemei, S | 1 |
| Cortelli, P | 1 |
| Cevoli, S | 1 |
| Pierangeli, G | 1 |
| Favoni, V | 1 |
| Lisotto, C | 1 |
| Usai, S | 1 |
| Frediani, F | 1 |
| Di Fiore, P | 1 |
| D'Arrigo, G | 1 |
| Tassorelli, C | 1 |
| Sances, G | 1 |
| Cainazzo, MM | 1 |
| Baraldi, C | 1 |
| Sarchielli, P | 1 |
| Corbelli, I | 1 |
| De Vanna, G | 1 |
| Tedeschi, G | 1 |
| Russo, A | 1 |
| Lau, CI | 1 |
| Wang, YF | 1 |
| Bérczi, B | 1 |
| Sneath, P | 1 |
| Engel, ER | 1 |
| Cheng, J | 1 |
| Lipton, RB | 2 |
| Schmidt, P | 1 |
| Diener, HC | 2 |
| Diener, H- | 1 |
| Tepper, DE | 1 |
| Derry, S | 2 |
| Rabbie, R | 2 |
| Moore, RA | 2 |
| Dubey, R | 1 |
| Martini, LG | 1 |
| Christie, M | 1 |
| Garnock-Jones, KP | 1 |
| Affaitati, G | 1 |
| Martelletti, P | 1 |
| Lopopolo, M | 1 |
| Tana, C | 1 |
| Massimini, F | 1 |
| Cipollone, F | 1 |
| Lapenna, D | 1 |
| Giamberardino, MA | 1 |
| Costantini, R | 1 |
| Gulseren, D | 1 |
| Sahin, EB | 1 |
| Bozdogan, O | 1 |
| Artuz, F | 1 |
| Buettner, C | 1 |
| Melo-Carrillo, A | 1 |
| Burstein, R | 2 |
| Schoenen, J | 1 |
| De Klippel, N | 1 |
| Giurgea, S | 1 |
| Herroelen, L | 1 |
| Jacquy, J | 1 |
| Louis, P | 1 |
| Monseu, G | 1 |
| Vandenheede, M | 1 |
| Jakubowski, M | 1 |
| Haag, G | 1 |
| Silberstein, SD | 1 |
| Comoglu, T | 1 |
| Dogan, A | 1 |
| Comoglu, S | 1 |
| Basci, N | 1 |
| Grosberg, B | 1 |
| Singer, RP | 1 |
| Pearlman, SH | 1 |
| Sorrentino, JV | 1 |
| Quiring, JN | 1 |
| Saper, JR | 1 |
| Morillo, LE | 2 |
| Engindeniz, Z | 1 |
| Demircan, C | 1 |
| Karli, N | 1 |
| Armagan, E | 1 |
| Bulut, M | 1 |
| Aydin, T | 1 |
| Zarifoglu, M | 1 |
| Montagna, P | 1 |
| Gács, G | 1 |
| Lyczak, P | 1 |
| Schumann, G | 1 |
| Zöller, B | 1 |
| Mulder, LJ | 1 |
| Siegel, J | 1 |
| Edson, K | 1 |
| Vécsei, L | 1 |
| Gallacchi, G | 1 |
| Sági, I | 1 |
| Semjén, J | 1 |
| Tajti, J | 1 |
| Szok, D | 1 |
| Müller, M | 1 |
| Vadass, P | 1 |
| Kerékgyártó, M | 1 |
| Orssaud, C | 1 |
| Roche, O | 1 |
| El Dirani, H | 1 |
| Allali, J | 1 |
| Dufier, JL | 1 |
| Dahlöf, C | 1 |
| Björkman, R | 1 |
| Hering, R | 1 |
| Couturier, EG | 1 |
| Steiner, TJ | 1 |
| McNeely, W | 1 |
| Goa, KL | 1 |
| Bigal, ME | 1 |
| Bordini, CA | 1 |
| Speciali, JG | 1 |
| Polliack, J | 1 |
| Szigethy, A | 1 |
| Dienes, L | 1 |
| Pradalier, A | 1 |
| Vincent, D | 1 |
| Karachalios, GN | 1 |
| Fotiadou, A | 1 |
| Chrisikos, N | 1 |
| Karabetsos, A | 1 |
| Kehagioglou, K | 1 |
| Messinger, HB | 1 |
| Massiou, H | 1 |
| Serrurier, D | 1 |
| Lasserre, O | 1 |
| Bousser, MG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| IM Ketorolac vs Diclofenac Potassium Powder for Oral Solution (Cambia) for the Acute Treatment of Severe Migraine[NCT02664116] | Phase 4 | 40 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | ||
| The Utility of Adding 1 L Intravenous Normal Saline to Standard 75 mg Intramuscular Diclofenac Potassium Injection in Patients Presented to the Emergency Department With an Acute Migraine Attack[NCT04287140] | 120 participants (Anticipated) | Interventional | 2020-04-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for diclofenac and Abdominal Migraine
| Article | Year |
|---|---|
Efficacy of ketorolac in the treatment of acute migraine attack: A systematic review and meta-analysis.
Topics: Caffeine; Dexamethasone; Diclofenac; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Pain; Ph | 2022 |
BET 2: Treating migraines with diclofenac instead of a triptan.
Topics: Adult; Diclofenac; Evidence-Based Emergency Medicine; Female; Humans; Migraine Disorders; Treatment | 2019 |
Topics: Analgesics; Aspirin; Diclofenac; Humans; Ibuprofen; Migraine Disorders; Pyrrolidines; Randomized Con | 2017 |
Diclofenac with or without an antiemetic for acute migraine headaches in adults.
Topics: Acute Disease; Adult; Analgesics; Antiemetics; Diclofenac; Drug Therapy, Combination; Female; Humans | 2013 |
Diclofenac potassium powder for oral solution: a review of its use in patients with acute migraine.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Controlled Clinical Trials as Topic; | 2014 |
[Self-medication of primary headaches].
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diclof | 2009 |
Meeting acute migraine treatment needs through novel treatment formulations.
Topics: Analgesics, Non-Narcotic; Diclofenac; Dihydroergotamine; Drug Administration Routes; Drug Delivery S | 2010 |
Diclofenac with or without an antiemetic for acute migraine headaches in adults.
Topics: Acute Disease; Adult; Analgesics; Antiemetics; Diclofenac; Drug Therapy, Combination; Humans; Hypera | 2012 |
Migraine headache.
Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Dicl | 2003 |
Migraine headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ergotamine; Humans; Ibuprofen; Indoles; Migrain | 2004 |
Diclofenac-potassium in migraine: a review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Humans; Migraine Diso | 1999 |
[Migraine and non-steroidal anti-inflammatory agents].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic | 1992 |
14 trials available for diclofenac and Abdominal Migraine
| Article | Year |
|---|---|
Self-administered subcutaneous diclofenac sodium in acute migraine attack: A randomized, double-blind, placebo-controlled dose-finding pilot study.
Topics: Diclofenac; Double-Blind Method; Humans; Infusions, Intravenous; Migraine Disorders; Pilot Projects | 2022 |
IM ketorolac vs diclofenac potassium powder for oral solution for the acute treatment of severe migraine: a randomized controlled trial.
Topics: Acute Disease; Administration, Oral; Adult; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Meth | 2020 |
Post Hoc Subanalysis of Two Randomized, Controlled Phase 3 Trials Evaluating Diclofenac Potassium for Oral Solution: Impact of Migraine-Associated Nausea and Prior Triptan Use on Efficacy.
Topics: Adult; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged | 2017 |
Almotriptan and its combination with aceclofenac for migraine attacks: a study of efficacy and the influence of auto-evaluated brush allodynia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Therapy, Combination; Female; Human | 2008 |
Formulation and evaluation of diclofenac potassium fast-disintegrating tablets and their clinical application in migraine patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diclofenac; Dosage Forms; Drug C | 2011 |
Efficacy and tolerability of a new powdered formulation of diclofenac potassium for oral solution for the acute treatment of migraine: results from the International Migraine Pain Assessment Clinical Trial (IMPACT).
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; | 2010 |
Intramuscular tramadol vs. diclofenac sodium for the treatment of acute migraine attacks in emergency department: a prospective, randomised, double-blind study.
Topics: Acute Disease; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Data Collection; | 2005 |
Efficacy and tolerability of diclofenac potassium sachets in migraine: a randomized, double-blind, cross-over study in comparison with diclofenac potassium tablets and placebo.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diclofenac | 2006 |
Diclofenac epolamine is effective in the treatment of acute migraine attacks. A randomized, crossover, double blind, placebo-controlled, clinical study.
Topics: Adult; Analgesics; Diclofenac; Double-Blind Method; Europe; Female; Humans; Male; Middle Aged; Migra | 2007 |
Diclofenac-K (50 and 100 mg) and placebo in the acute treatment of migraine.
Topics: Adolescent; Adult; Aged; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Female; | 1993 |
Acute treatment of migraine attacks: efficacy and safety of a nonsteroidal anti-inflammatory drug, diclofenac-potassium, in comparison to oral sumatriptan and placebo. The Diclofenac-K/Sumatriptan Migraine Study Group.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Dicl | 1999 |
[Migraine and non-steroidal anti-inflammatory agents].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic | 1992 |
Treatment of acute migraine attack with diclofenac sodium: a double-blind study.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Diclofenac; Double-Blind Method; Female; Huma | 1992 |
Effectiveness of oral diclofenac in the acute treatment of common migraine attacks: a double-blind study versus placebo.
Topics: Administration, Oral; Adult; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Mig | 1991 |
15 other studies available for diclofenac and Abdominal Migraine
| Article | Year |
|---|---|
2022 Taiwan Guidelines for Acute Treatment of Migraine.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin G | 2022 |
Non-steroidal anti-inflammatories for the acute treatment of migraine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Migraine Disorders | 2013 |
Duel-acting subcutaneous microemulsion formulation for improved migraine treatment with zolmitriptan and diclofenac: formulation and in vitro-in vivo characterization.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Emulsions; In Vitro Techniques; Male; | 2014 |
Use of Nonsteroidal Anti-Inflammatory Drugs for Symptomatic Treatment of Episodic Headache.
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Follow-Up Studies; H | 2017 |
An avoidable adverse drug reaction: Nicolau syndrome.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dopamine D2 Receptor Antagonists; Female | 2017 |
Terminating Migraine-Associated Allodynia Using Oral Suspension Diclofenac: A Prospective Non-Randomized Drug Trial.
Topics: Adolescent; Adult; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Hyperalgesia; Middle Aged; | 2017 |
Almotriptan efficacy in migraine with allodynia: a critique of Schoenen et al.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Therapy, Combination; Female; Human | 2009 |
[Painful ophthalmoplegia in children: Tolosa-Hunt syndrome or ophthalmoplegic migraine?].
Topics: Adolescent; Adrenal Cortex Hormones; Child, Preschool; Diclofenac; Female; Humans; Male; Migraine Di | 2007 |
Intramuscular diclofenac in late treatment of migraine.
Topics: Adult; Diclofenac; Drug Administration Schedule; Female; Humans; Injections, Intramuscular; Male; Mi | 1996 |
[Headache treatment in an emergency unit of the city of Ribeirão Preto, Brazil].
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroida | 1999 |
[Migraine therapy. NSAID are included as first choice].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Migraine Disorders | 2001 |
[Non-steroidal anti-inflammatory drugs with new characteristics. Rapid help in migraine].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Clinical Trials as Topic; Diclofen | 2002 |
Chronic recurrent headaches.
Topics: Diclofenac; Drug Therapy, Combination; Humans; Migraine Disorders; Phenylacetates; Trifluoperazine | 1979 |
The relation between atypical migraine and multiphasic oral contraceptives.
Topics: Adult; Contraceptives, Oral; Diclofenac; Domperidone; Drug Evaluation; Female; Humans; Menstruation; | 1992 |
Trial of oral diclofenac for the acute treatment of common migraine attacks.
Topics: Diclofenac; Humans; Migraine Disorders; Research Design | 1992 |