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dichlorvos and Nerve Degeneration

dichlorvos has been researched along with Nerve Degeneration in 5 studies

Dichlorvos: An organophosphorus insecticide that inhibits ACETYLCHOLINESTERASE.
dichlorvos : An alkenyl phosphate that is the 2,2-dichloroethenyl ester of dimethyl phosphate.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"The induction of central-peripheral distal axonopathy in hens singly dosed with some organophosphorus (OP) compounds, such as di-n-butyl-2,2-dichlorovinyl phosphate (DBDCVP), requires greater than 80% organophosphorylation and subsequent intramolecular rearrangement ("aging") of a protein [neuropathy target esterase (NTE)] in the axon."1.27Progressive deficit of retrograde axonal transport is associated with the pathogenesis of di-n-butyl dichlorvos axonopathy. ( Lotti, M; Moretto, A; Sabri, MI; Spencer, PS, 1987)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Binukumar, BK1
Gupta, N1
Sunkaria, A1
Kandimalla, R1
Wani, WY1
Sharma, DR1
Bal, A1
Gill, KD3
Kaur, P1
Radotra, B1
Minz, RW1
Dambska, M1
Maślińska, D1
Choudhary, S1
Joshi, K1
Moretto, A1
Lotti, M1
Sabri, MI1
Spencer, PS1

Other Studies

5 other studies available for dichlorvos and Nerve Degeneration

ArticleYear
Protective efficacy of coenzyme Q10 against DDVP-induced cognitive impairments and neurodegeneration in rats.
    Neurotoxicity research, 2012, Volume: 21, Issue:4

    Topics: Animals; Avoidance Learning; Cognition Disorders; Dichlorvos; Disease Models, Animal; Drug Administr

2012
Impaired mitochondrial energy metabolism and neuronal apoptotic cell death after chronic dichlorvos (OP) exposure in rat brain.
    Neurotoxicology, 2007, Volume: 28, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Brain; Calcium; Caspase 3; Cytochromes c; Deoxyguan

2007
Effect of dichlorvos (ddvp) intoxication of rabbit brain.
    Neuropatologia polska, 1982, Volume: 20, Issue:1-2

    Topics: Animals; Axons; Corpus Callosum; Dichlorvos; Microscopy, Electron; Nerve Degeneration; Neuroglia; Ra

1982
Possible role of enhanced microtubule phosphorylation in dichlorvos induced delayed neurotoxicity in rat.
    Brain research, 2001, Apr-06, Volume: 897, Issue:1-2

    Topics: Animals; Blood Platelets; Brain Chemistry; Calmodulin; Carboxylic Ester Hydrolases; Creatine Kinase;

2001
Progressive deficit of retrograde axonal transport is associated with the pathogenesis of di-n-butyl dichlorvos axonopathy.
    Journal of neurochemistry, 1987, Volume: 49, Issue:5

    Topics: Animals; Axonal Transport; Axons; Carboxylic Ester Hydrolases; Chickens; Dichlorvos; Female; Kinetic

1987