dichlorphenamide has been researched along with Familial Periodic Paralysis in 7 studies
Dichlorphenamide: A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
diclofenamide : A sulfonamide that is benzene-1,3-disulfonamide in which the hydrogens at positions 4 and 5 are substituted by chlorine. An oral carbonic anhydrase inhibitor, it partially suppresses the secretion (inflow) of aqueous humor in the eye and so reduces intraocular pressure. It is used for the treatment of glaucoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Skeletal muscle ion channelopathies are rare genetic diseases mainly characterized by myotonia (muscle stiffness) or periodic paralysis (muscle weakness)." | 3.01 | Drug repurposing in skeletal muscle ion channelopathies. ( Altamura, C; Campanale, C; Desaphy, JF; Laghetti, P; Saltarella, I, 2023) |
| " Common adverse events (AEs) were paresthesia and cognition-related events, which typically first occurred within 1 month of blinded treatment initiation and in rare cases led to treatment discontinuation." | 3.01 | Long-term efficacy and safety of dichlorphenamide for treatment of primary periodic paralysis. ( Ciafaloni, E; Cohen, F; Griggs, RC; Hanna, MG; Johnson, NE; Sansone, VA; Shieh, PB; Statland, JM, 2021) |
| "Dichlorphenamide was effective and well tolerated in two studies, including one with adolescents." | 2.90 | Efficacy and Safety of Dichlorphenamide for Primary Periodic Paralysis in Adolescents Compared With Adults. ( Ciafaloni, E; Cohen, F; Griggs, R, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Altamura, C | 2 |
| Saltarella, I | 2 |
| Campanale, C | 2 |
| Laghetti, P | 2 |
| Desaphy, JF | 2 |
| Ciafaloni, E | 3 |
| Cohen, F | 2 |
| Griggs, R | 1 |
| Sansone, VA | 2 |
| Johnson, NE | 1 |
| Hanna, MG | 2 |
| Statland, JM | 1 |
| Shieh, PB | 1 |
| Griggs, RC | 2 |
| Burge, J | 1 |
| McDermott, MP | 1 |
| Smith, PC | 1 |
| Herr, B | 1 |
| Tawil, R | 1 |
| Pandya, S | 1 |
| Kissel, J | 1 |
| Shieh, P | 1 |
| Ralph, JW | 1 |
| Amato, A | 1 |
| Cannon, SC | 1 |
| Trivedi, J | 1 |
| Barohn, R | 1 |
| Crum, B | 1 |
| Mitsumoto, H | 1 |
| Pestronk, A | 1 |
| Meola, G | 1 |
| Conwit, R | 1 |
| Fontaine, B | 1 |
| Phillips, LH | 1 |
| Kold, A | 1 |
| Sander, C | 1 |
1 review available for dichlorphenamide and Familial Periodic Paralysis
| Article | Year |
|---|---|
Drug repurposing in skeletal muscle ion channelopathies.
Topics: Channelopathies; Dichlorphenamide; Drug Repositioning; Humans; Mexiletine; Muscle, Skeletal; Mutatio | 2023 |
Drug repurposing in skeletal muscle ion channelopathies.
Topics: Channelopathies; Dichlorphenamide; Drug Repositioning; Humans; Mexiletine; Muscle, Skeletal; Mutatio | 2023 |
Drug repurposing in skeletal muscle ion channelopathies.
Topics: Channelopathies; Dichlorphenamide; Drug Repositioning; Humans; Mexiletine; Muscle, Skeletal; Mutatio | 2023 |
Drug repurposing in skeletal muscle ion channelopathies.
Topics: Channelopathies; Dichlorphenamide; Drug Repositioning; Humans; Mexiletine; Muscle, Skeletal; Mutatio | 2023 |
3 trials available for dichlorphenamide and Familial Periodic Paralysis
| Article | Year |
|---|---|
Efficacy and Safety of Dichlorphenamide for Primary Periodic Paralysis in Adolescents Compared With Adults.
Topics: Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Child; Dichlorphenamide; Double-Blind Method | 2019 |
Long-term efficacy and safety of dichlorphenamide for treatment of primary periodic paralysis.
Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Double-Blind Method; Female; Humans; M | 2021 |
Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis.
Topics: Adult; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Double-Blind Method; Female; Follow-Up Studi | 2016 |
3 other studies available for dichlorphenamide and Familial Periodic Paralysis
| Article | Year |
|---|---|
A newly approved drug for a rare group of diseases: Dichlorphenamide for periodic paralysis.
Topics: Dichlorphenamide; Humans; Hypokalemic Periodic Paralysis; Paralyses, Familial Periodic; Paralysis | 2016 |
[Treatment of familial hypokalemic paralysis with carbon dioxide anhydrase inhibitors].
Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Humans; Hypokalemia; Male; Mi | 1986 |
[Diclofenamid in paroxysmal hypokalemic paralysis].
Topics: Child; Dichlorphenamide; Humans; Male; Paralyses, Familial Periodic; Potassium | 1986 |