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dichlororibofuranosylbenzimidazole and Scleroderma, Systemic

dichlororibofuranosylbenzimidazole has been researched along with Scleroderma, Systemic in 1 studies

Dichlororibofuranosylbenzimidazole: An RNA polymerase II transcriptional inhibitor. This compound terminates transcription prematurely by selective inhibition of RNA synthesis. It is used in research to study underlying mechanisms of cellular regulation.

Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reimer, G1
Scheer, U1
Peters, JM1
Tan, EM1

Other Studies

1 other study available for dichlororibofuranosylbenzimidazole and Scleroderma, Systemic

ArticleYear
Immunolocalization and partial characterization of a nucleolar autoantigen (PM-Scl) associated with polymyositis/scleroderma overlap syndromes.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Dec-15, Volume: 137, Issue:12

    Topics: Animals; Antigens, Nuclear; Autoantibodies; Autoantigens; Cell Cycle; Cell Nucleolus; Dactinomycin;

1986