dichlororibofuranosylbenzimidazole has been researched along with Di Guglielmo Disease in 2 studies
Dichlororibofuranosylbenzimidazole: An RNA polymerase II transcriptional inhibitor. This compound terminates transcription prematurely by selective inhibition of RNA synthesis. It is used in research to study underlying mechanisms of cellular regulation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Friend virus-transformed murine erythroleukemia (MEL) cells are a useful system for studying the regulation of erythroid growth and differentiation." | 1.29 | RNA polymerase II inhibitor, 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) causes erythroleukemic differentiation and transcriptional activation of erythroid genes. ( Barth, D; Hensold, JO; Stratton, CA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hensold, JO | 1 |
| Barth, D | 1 |
| Stratton, CA | 1 |
| Mukherjee, R | 1 |
| Molloy, GR | 1 |
2 other studies available for dichlororibofuranosylbenzimidazole and Di Guglielmo Disease
| Article | Year |
|---|---|
RNA polymerase II inhibitor, 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) causes erythroleukemic differentiation and transcriptional activation of erythroid genes.
Topics: Animals; Cell Differentiation; Cell Division; Chromosomal Proteins, Non-Histone; Dichlororibofuranos | 1996 |
5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits transcription of the beta-hemoglobin gene in vivo at initiation.
Topics: Animals; Cell Line; Cell Nucleus; Dichlororibofuranosylbenzimidazole; Genes; Hemoglobins; Kinetics; | 1987 |