Page last updated: 2024-10-26

dichlorodiphenyl dichloroethylene and Obesity

dichlorodiphenyl dichloroethylene has been researched along with Obesity in 28 studies

Dichlorodiphenyl Dichloroethylene: An organochlorine pesticide, it is the ethylene metabolite of DDT.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
" Their daughters aged 44-53 years had their height, weight, and waist circumference measured during a home visit to evaluate associations of daughters' adiposity and relative risk of overweight and obesity with their mothers' prenatal serum levels of DDT and DDE quantified by gas chromatograph-tandem mass spectrometer (n = 511)."7.96Association between maternal exposure to the pesticide dichlorodiphenyltrichloroethane (DDT) and risk of obesity in middle age. ( Cirillo, PM; Cohn, BA; Krigbaum, NY; La Merrill, MA, 2020)
"In utero exposure to endocrine disrupting compounds including dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) has been hypothesized to increase risk of obesity later in life."7.79In utero DDT and DDE exposure and obesity status of 7-year-old Mexican-American children in the CHAMACOS cohort. ( Aguilar Schall, R; Barr, D; Bradman, A; Eskenazi, B; Harley, KG; Warner, M, 2013)
"We explored whether prenatal organochlorine compound (OC) concentrations [polychlorinated biphenyls (PCBs), dichlorodiphenyldichloroethylene (DDE), and dichlorodiphenyltrichloroethane (DDT)] were associated with overweight at 6."7.78Prenatal concentrations of polychlorinated biphenyls, DDE, and DDT and overweight in children: a prospective birth cohort study. ( Grimalt, JO; Martinez, D; Mendez, MA; Sunyer, J; Torrent, M; Valvi, D; Vrijheid, M, 2012)
"Our objective was to systematically review the literature on the association between exposure to the pesticide DDT and its metabolites and obesity to develop hazard identification conclusions."4.95Association between Exposure to ( Cano-Sancho, G; La Merrill, MA; Salmon, AG, 2017)
" Their daughters aged 44-53 years had their height, weight, and waist circumference measured during a home visit to evaluate associations of daughters' adiposity and relative risk of overweight and obesity with their mothers' prenatal serum levels of DDT and DDE quantified by gas chromatograph-tandem mass spectrometer (n = 511)."3.96Association between maternal exposure to the pesticide dichlorodiphenyltrichloroethane (DDT) and risk of obesity in middle age. ( Cirillo, PM; Cohn, BA; Krigbaum, NY; La Merrill, MA, 2020)
"This study was aimed to evaluate possible obesogenic and diabetogenic impact of highly increased serum level of persistent organochlorinated pollutants POPs, such as polychlorinated biphenyls (PCBs), dichlorodiethyl-dichloroethylene (p,p'-DDE), and hexachlorobenzene (HCB), on the level of obesity markers (cholesterol and triglyceride level in serum, and body mass index [BMI]) and diabetes markers (fasting glucose and fasting insulin in serum) in inhabitants of Eastern Slovakia."3.80Obesogenic and diabetogenic impact of high organochlorine levels (HCB, p,p'-DDE, PCBs) on inhabitants in the highly polluted Eastern Slovakia. ( Drobna, B; Gasperikova, D; Huckova, M; Imrich, R; Klimes, I; Kocan, A; Langer, P; Radikova, Z; Trnovec, T; Ukropec, J, 2014)
"In utero exposure to endocrine disrupting compounds including dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) has been hypothesized to increase risk of obesity later in life."3.79In utero DDT and DDE exposure and obesity status of 7-year-old Mexican-American children in the CHAMACOS cohort. ( Aguilar Schall, R; Barr, D; Bradman, A; Eskenazi, B; Harley, KG; Warner, M, 2013)
"We explored whether prenatal organochlorine compound (OC) concentrations [polychlorinated biphenyls (PCBs), dichlorodiphenyldichloroethylene (DDE), and dichlorodiphenyltrichloroethane (DDT)] were associated with overweight at 6."3.78Prenatal concentrations of polychlorinated biphenyls, DDE, and DDT and overweight in children: a prospective birth cohort study. ( Grimalt, JO; Martinez, D; Mendez, MA; Sunyer, J; Torrent, M; Valvi, D; Vrijheid, M, 2012)
"Chlordecone is a persistent organochlorine insecticide with estrogenic properties that was used in the French West Indies (1973-1993) and is still present in the soil and the water and food consumed by the local population."1.72Prenatal and childhood exposure to chlordecone and adiposity of seven-year-old children in the Timoun mother-child cohort study in Guadeloupe (French West Indies). ( Cordier, S; Costet, N; Kadhel, P; Lafontaine, A; Michineau, L; Monfort, C; Multigner, L; Rouget, F; Thomé, JP, 2022)
"Obesity has become a very important public health problem and is increasing globally."1.72Investigation of obesogenic effects of hexachlorobenzene, DDT and DDE in male rats. ( Al-Obaidi, ZAF; Erdogan, CS; Gemici, B; Özgün, HB; Sandal, S; Sümer, E; Yilmaz, B, 2022)
"The prevalence of obesity has raised global concerns."1.51Pectin reduces environmental pollutant-induced obesity in mice through regulating gut microbiota: A case study of p,p'-DDE. ( Li, P; Liang, Y; Liu, D; Ma, X; Wang, P; Zhai, W; Zhan, J; Zhou, Z, 2019)
"Adjusted odds ratios (ORs) for breast cancer comparing the highest to lowest third of DDE were 1."1.31Dichlorodiphenyldichloroethene, polychlorinated biphenyls, and breast cancer among African-American and white women in North Carolina. ( Beach, J; DeVoto, E; Duell, EJ; Edmiston, S; Jackson, S; Millikan, R; Newman, B; Savitz, DA; Tse, CK, 2000)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.14)18.7374
1990's0 (0.00)18.2507
2000's3 (10.71)29.6817
2010's17 (60.71)24.3611
2020's6 (21.43)2.80

Authors

AuthorsStudies
Costet, N2
Lafontaine, A1
Rouget, F2
Michineau, L1
Monfort, C2
Thomé, JP1
Kadhel, P1
Multigner, L1
Cordier, S1
Al-Obaidi, ZAF1
Erdogan, CS1
Sümer, E1
Özgün, HB1
Gemici, B1
Sandal, S1
Yilmaz, B1
Rouxel, E1
Audouze, K1
Cirugeda, L1
Gaudreau, E1
Grimalt, JO2
Ibarluzea, J1
Lainé, F1
Llop, S1
Lopez-Espinosa, MJ1
Santa-Marina, L1
Vrijheid, M2
Chevrier, C1
Casas, M1
Warembourg, C1
Liang, Y2
Liu, D2
Zhan, J2
Luo, M1
Han, J1
Wang, P2
Zhou, Z2
La Merrill, MA3
Krigbaum, NY1
Cirillo, PM1
Cohn, BA1
Kladnicka, I1
Cedikova, M1
Jedlicka, J1
Kohoutova, M1
Muller, L1
Plavinova, I1
Kripnerova, M1
Bludovska, M1
Kuncova, J1
Mullerova, D1
Pestana, D2
Teixeira, D2
Meireles, M1
Marques, C1
Norberto, S1
Sá, C2
Fernandes, VC1
Correia-Sá, L1
Faria, A2
Guardão, L1
Guimarães, JT1
Cooper, WN1
Sandovici, I1
Domingues, VF1
Delerue-Matos, C1
Monteiro, R1
Constância, M1
Calhau, C2
Cano-Sancho, G1
Salmon, AG1
Lind, PM2
Salihovic, S2
van Bavel, B2
Lind, L2
Barrett, JR1
Ma, X1
Li, P1
Zhai, W1
Warner, M2
Aguilar Schall, R1
Harley, KG1
Bradman, A1
Barr, D1
Eskenazi, B2
Roos, V1
Rönn, M1
Kullberg, J1
Johansson, L1
Ahlström, H1
Tang-Péronard, JL2
Heitmann, BL2
Andersen, HR2
Steuerwald, U1
Grandjean, P1
Weihe, P1
Jensen, TK2
Langer, P1
Ukropec, J1
Kocan, A1
Drobna, B1
Radikova, Z1
Huckova, M1
Imrich, R1
Gasperikova, D1
Klimes, I1
Trnovec, T1
Dirinck, EL1
Dirtu, AC1
Govindan, M1
Covaci, A1
Van Gaal, LF1
Jorens, PG1
Arrebola, JP1
Ocaña-Riola, R1
Arrebola-Moreno, AL1
Fernández-Rodríguez, M1
Martin-Olmedo, P1
Fernández, MF1
Olea, N1
Legler, J1
Fletcher, T1
Govarts, E1
Porta, M1
Blumberg, B1
Heindel, JJ1
Trasande, L1
Heggeseth, B1
Harley, K1
Jewell, N1
Ried-Larsen, M1
Grøntved, A1
Andersen, LB1
Timmermann, CA1
Nielsen, F1
Rodríguez-Alcalá, LM1
Pimentel, LL1
Gomes, A1
Aminov, Z1
Haase, R1
Carpenter, DO1
Karmaus, W1
Osuch, JR1
Eneli, I1
Mudd, LM1
Zhang, J1
Mikucki, D1
Haan, P1
Davis, S1
Valvi, D1
Mendez, MA1
Martinez, D1
Torrent, M1
Sunyer, J1
Wolff, MS1
Anderson, HA1
Britton, JA1
Rothman, N1
Millikan, R1
DeVoto, E1
Duell, EJ1
Tse, CK1
Savitz, DA1
Beach, J1
Edmiston, S1
Jackson, S1
Newman, B1
Backman, L1
Kolmodin-Hedman, B1
Kontek, M1
Paradowski, S1
Pietraszek, Z1
Kubacki, SJ1
Cieślicki, J1
Sniezyński, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Endocrine Disrupting Environmental Chemicals: From Accumulation to Their Role in the Global Neuro-endocrine Epidemic of Obesity and Its Metabolic Consequences"[NCT01778868]203 participants (Actual)Observational2009-08-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dichlorodiphenyl dichloroethylene and Obesity

ArticleYear
Association between Exposure to
    Environmental health perspectives, 2017, 09-18, Volume: 125, Issue:9

    Topics: DDT; Dichlorodiphenyl Dichloroethylene; Environmental Exposure; Environmental Pollutants; Humans; Ob

2017

Other Studies

27 other studies available for dichlorodiphenyl dichloroethylene and Obesity

ArticleYear
Prenatal and childhood exposure to chlordecone and adiposity of seven-year-old children in the Timoun mother-child cohort study in Guadeloupe (French West Indies).
    Environmental health : a global access science source, 2022, 04-19, Volume: 21, Issue:1

    Topics: Adiposity; Child; Chlordecone; Cohort Studies; Dichlorodiphenyl Dichloroethylene; Female; Guadeloupe

2022
Investigation of obesogenic effects of hexachlorobenzene, DDT and DDE in male rats.
    General and comparative endocrinology, 2022, 10-01, Volume: 327

    Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Body Weight; DDT; Dichlorodiphenyl Dichloroet

2022
Prenatal exposure to multiple persistent organic pollutants in association with adiposity markers and blood pressure in preadolescents.
    Environment international, 2023, Volume: 178

    Topics: Adiposity; Adolescent; Bayes Theorem; Blood Pressure; Dichlorodiphenyl Dichloroethylene; Environment

2023
New insight into the mechanism of POP-induced obesity: Evidence from DDE-altered microbiota.
    Chemosphere, 2020, Volume: 244

    Topics: Animals; Dichlorodiphenyl Dichloroethylene; Dysbiosis; Environmental Pollutants; Gastrointestinal Mi

2020
Association between maternal exposure to the pesticide dichlorodiphenyltrichloroethane (DDT) and risk of obesity in middle age.
    International journal of obesity (2005), 2020, Volume: 44, Issue:8

    Topics: Adiposity; Adult; Body Mass Index; California; DDT; Dichlorodiphenyl Dichloroethylene; Female; Human

2020
Chronic DDE Exposure Modifies Mitochondrial Respiration during Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Mature Adipocytes.
    Biomolecules, 2021, 07-21, Volume: 11, Issue:8

    Topics: Adipocytes; Adipogenesis; Cell Differentiation; Cells, Cultured; Dichlorodiphenyl Dichloroethylene;

2021
Adipose tissue dysfunction as a central mechanism leading to dysmetabolic obesity triggered by chronic exposure to p,p'-DDE.
    Scientific reports, 2017, 06-01, Volume: 7, Issue:1

    Topics: Animals; Cytokines; Dichlorodiphenyl Dichloroethylene; Endocrine Disruptors; Gene Expression; Inflam

2017
The association between p,p'-DDE levels and left ventricular mass is mainly mediated by obesity.
    Environmental research, 2018, Volume: 160

    Topics: Adiposity; Aged; Aged, 80 and over; Blood Glucose; Cohort Studies; Dichlorodiphenyl Dichloroethylene

2018
DDT and Obesity in Humans: Exploring the Evidence in a New Way.
    Environmental health perspectives, 2018, 02-22, Volume: 126, Issue:2

    Topics: DDT; Dichlorodiphenyl Dichloroethylene; Humans; Insecticides; Obesity

2018
Pectin reduces environmental pollutant-induced obesity in mice through regulating gut microbiota: A case study of p,p'-DDE.
    Environment international, 2019, Volume: 130

    Topics: Animals; Dichlorodiphenyl Dichloroethylene; Dyslipidemias; Environmental Pollutants; Feces; Gastroin

2019
In utero DDT and DDE exposure and obesity status of 7-year-old Mexican-American children in the CHAMACOS cohort.
    Environmental health perspectives, 2013, Volume: 121, Issue:5

    Topics: Child; Cohort Studies; DDT; Dichlorodiphenyl Dichloroethylene; Female; Fetus; Humans; Longitudinal S

2013
Circulating levels of persistent organic pollutants in relation to visceral and subcutaneous adipose tissue by abdominal MRI.
    Obesity (Silver Spring, Md.), 2013, Volume: 21, Issue:2

    Topics: Aged; Cross-Sectional Studies; Dichlorodiphenyl Dichloroethylene; Environmental Pollutants; Female;

2013
Association between prenatal polychlorinated biphenyl exposure and obesity development at ages 5 and 7 y: a prospective cohort study of 656 children from the Faroe Islands.
    The American journal of clinical nutrition, 2014, Volume: 99, Issue:1

    Topics: Body Mass Index; Body Weight; Child; Child, Preschool; Denmark; Dichlorodiphenyl Dichloroethylene; F

2014
Obesogenic and diabetogenic impact of high organochlorine levels (HCB, p,p'-DDE, PCBs) on inhabitants in the highly polluted Eastern Slovakia.
    Endocrine regulations, 2014, Volume: 48, Issue:1

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Dichlorodiphenyl Dichloroethylene; Environmental Pollutants;

2014
Exposure to persistent organic pollutants: relationship with abnormal glucose metabolism and visceral adiposity.
    Diabetes care, 2014, Volume: 37, Issue:7

    Topics: Adipose Tissue; Adiposity; Adolescent; Adult; Aged; Aged, 80 and over; Body Composition; Dichlorodip

2014
Associations of accumulated exposure to persistent organic pollutants with serum lipids and obesity in an adult cohort from Southern Spain.
    Environmental pollution (Barking, Essex : 1987), 2014, Volume: 195

    Topics: Adult; Dichlorodiphenyl Dichloroethylene; Environmental Exposure; Environmental Pollutants; Hazardou

2014
Obesity, diabetes, and associated costs of exposure to endocrine-disrupting chemicals in the European Union.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Child; Cost of Illness; Diabetes Mellitus; Dichlorodiphenyl Dichloro

2015
Detecting Associations between Early-Life DDT Exposures and Childhood Growth Patterns: A Novel Statistical Approach.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Body Mass Index; Cohort Studies; DDT; Dichlorodiphenyl Dichloroethylene; Endocrine Disruptors; Femal

2015
Associations between Exposure to Persistent Organic Pollutants in Childhood and Overweight up to 12 Years Later in a Low Exposed Danish Population.
    Obesity facts, 2015, Volume: 8, Issue:4

    Topics: Adolescent; Child; Denmark; Dichlorodiphenyl Dichloroethylene; Environmental Pollutants; Female; Hex

2015
Endocrine Disruptor DDE Associated with a High-Fat Diet Enhances the Impairment of Liver Fatty Acid Composition in Rats.
    Journal of agricultural and food chemistry, 2015, Oct-28, Volume: 63, Issue:42

    Topics: Adipose Tissue; Animals; Dichlorodiphenyl Dichloroethylene; Diet, High-Fat; Endocrine Disruptors; Fa

2015
Diabetes in Native Americans: elevated risk as a result of exposure to polychlorinated biphenyls (PCBs).
    Reviews on environmental health, 2016, Volume: 31, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Diabetes Mellitus; Dichlorodiphenyl Dichloroethylene; En

2016
Maternal levels of dichlorodiphenyl-dichloroethylene (DDE) may increase weight and body mass index in adult female offspring.
    Occupational and environmental medicine, 2009, Volume: 66, Issue:3

    Topics: Adult; Adult Children; Animals; Body Height; Body Mass Index; Body Weight; Cohort Studies; Dichlorod

2009
Prenatal concentrations of polychlorinated biphenyls, DDE, and DDT and overweight in children: a prospective birth cohort study.
    Environmental health perspectives, 2012, Volume: 120, Issue:3

    Topics: Adult; Body Mass Index; Child; Chromatography, Gas; Cohort Studies; DDT; Dichlorodiphenyl Dichloroet

2012
Pharmacokinetic variability and modern epidemiology--the example of dichlorodiphenyltrichloroethane, body mass index, and birth cohort.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:10

    Topics: Adipose Tissue; Body Mass Index; Carcinogens, Environmental; Cohort Studies; Cross-Sectional Studies

2007
Dichlorodiphenyldichloroethene, polychlorinated biphenyls, and breast cancer among African-American and white women in North Carolina.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2000, Volume: 9, Issue:11

    Topics: Adult; Aged; Black People; Breast Feeding; Breast Neoplasms; Case-Control Studies; Confounding Facto

2000
Concentration of DDT and DDE in plasma and subcutaneous adipose tissue before and after intestinal bypass operation for treatment of obesity.
    Toxicology and applied pharmacology, 1978, Volume: 46, Issue:3

    Topics: Adipose Tissue; Body Weight; DDT; Dichlorodiphenyl Dichloroethylene; Female; Humans; Ileostomy; Jeju

1978
[Chlorinated hydrocarbons in adipose tissue of persons with gastrointestinal diseases].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1973, Jun-04, Volume: 28, Issue:23

    Topics: Adipose Tissue; Adult; Aged; DDT; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane;

1973