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dichlorodiphenyl dichloroethylene and Carcinoma

dichlorodiphenyl dichloroethylene has been researched along with Carcinoma in 3 studies

Dichlorodiphenyl Dichloroethylene: An organochlorine pesticide, it is the ethylene metabolite of DDT.

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
"The adrenolytic agent mitotane [o,p'-DDD or 1,1-(o,p'-dichlorodiphenyl)-2, 2-dichloroethane] has been employed in the nonsurgical treatment of patients with adrenal carcinoma for several decades."3.69A high-pressure liquid chromatographic method for measuring mitotane [1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethane] and its metabolite 1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethene in plasma. ( Andersen, A; Nome, O; Slørdal, L; Vesterhus, L; Warren, DJ, 1995)
"Aminoglutethimide was examined only for effects on CYP11A activity and was shown to inhibit pregnenolone formation (20 microM: 61 +/- 4% of control)."1.31Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. ( Johansson, MK; Lund, BO; Sanderson, JT, 2002)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersen, A1
Warren, DJ1
Nome, O1
Vesterhus, L1
Slørdal, L1
Johansson, MK1
Sanderson, JT1
Lund, BO1
Touitou, Y1
Moolenaar, AJ1
Bogdan, A1
Auzéby, A1
Luton, JP1

Other Studies

3 other studies available for dichlorodiphenyl dichloroethylene and Carcinoma

ArticleYear
A high-pressure liquid chromatographic method for measuring mitotane [1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethane] and its metabolite 1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethene in plasma.
    Therapeutic drug monitoring, 1995, Volume: 17, Issue:5

    Topics: Absorption; Adolescent; Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; Carcinoma; Chroma

1995
Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line.
    Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:2

    Topics: Adrenal Cortex Neoplasms; Aminoglutethimide; Carcinoma; Chromatography, High Pressure Liquid; Colfor

2002
o,p'-DDD (mitotane) treatment for Cushing's syndrome: adrenal drug concentration and inhibition in vitro of steroid synthesis.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Carcinoma; Child; Cort

1985