dichlorodiphenyl dichloroethylene and Carcinoma, Anaplastic studies

dichlorodiphenyl dichloroethylene and Carcinoma, Anaplastic

Dichlorodiphenyl Dichloroethylene: An organochlorine pesticide, it is the ethylene metabolite of DDT.

Research Excerpts

Excerpt	Relevance	Reference
"The adrenolytic agent mitotane [o,p'-DDD or 1,1-(o,p'-dichlorodiphenyl)-2, 2-dichloroethane] has been employed in the nonsurgical treatment of patients with adrenal carcinoma for several decades."	3.69	A high-pressure liquid chromatographic method for measuring mitotane [1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethane] and its metabolite 1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethene in plasma. ( Andersen, A; Nome, O; Slørdal, L; Vesterhus, L; Warren, DJ, 1995)
"Aminoglutethimide was examined only for effects on CYP11A activity and was shown to inhibit pregnenolone formation (20 microM: 61 +/- 4% of control)."	1.31	Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. ( Johansson, MK; Lund, BO; Sanderson, JT, 2002)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (33.33)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

1 (33.33)

18.7374

1990's

1 (33.33)

18.2507

2000's

1 (33.33)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Andersen, A	1
Warren, DJ	1
Nome, O	1
Vesterhus, L	1
Slørdal, L	1
Johansson, MK	1
Sanderson, JT	1
Lund, BO	1
Touitou, Y	1
Moolenaar, AJ	1
Bogdan, A	1
Auzéby, A	1
Luton, JP	1

Studies

Andersen, A

Warren, DJ

Nome, O

Vesterhus, L

Slørdal, L

Johansson, MK

Sanderson, JT

Lund, BO

Touitou, Y

Moolenaar, AJ

Bogdan, A

Auzéby, A

Luton, JP

Other Studies

3 other studies available for dichlorodiphenyl dichloroethylene and Carcinoma, Anaplastic

Article	Year
A high-pressure liquid chromatographic method for measuring mitotane [1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethane] and its metabolite 1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethene in plasma. Therapeutic drug monitoring, 1995, Volume: 17, Issue:5 Topics: Absorption; Adolescent; Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; Carcinoma; Chroma	1995
Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:2 Topics: Adrenal Cortex Neoplasms; Aminoglutethimide; Carcinoma; Chromatography, High Pressure Liquid; Colfor	2002
o,p'-DDD (mitotane) treatment for Cushing's syndrome: adrenal drug concentration and inhibition in vitro of steroid synthesis. European journal of clinical pharmacology, 1985, Volume: 29, Issue:4 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Carcinoma; Child; Cort	1985

Article

Year

A high-pressure liquid chromatographic method for measuring mitotane [1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethane] and its metabolite 1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethene in plasma.

Therapeutic drug monitoring, 1995, Volume: 17, Issue:5

Topics: Absorption; Adolescent; Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; Carcinoma; Chroma

1995

Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line.

Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:2

Topics: Adrenal Cortex Neoplasms; Aminoglutethimide; Carcinoma; Chromatography, High Pressure Liquid; Colfor

2002

o,p'-DDD (mitotane) treatment for Cushing's syndrome: adrenal drug concentration and inhibition in vitro of steroid synthesis.

European journal of clinical pharmacology, 1985, Volume: 29, Issue:4

Topics: 17-alpha-Hydroxyprogesterone; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Carcinoma; Child; Cort

1985