dichlorodiphenyl dichloroethylene has been researched along with Adrenal Cortex Neoplasms in 5 studies
Dichlorodiphenyl Dichloroethylene: An organochlorine pesticide, it is the ethylene metabolite of DDT.
Adrenal Cortex Neoplasms: Tumors or cancers of the ADRENAL CORTEX.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitotane is the only approved drug for treatment of adrenocortical carcinoma." | 9.17 | Comparison of two mitotane starting dose regimens in patients with advanced adrenocortical carcinoma. ( Allolio, B; Baudin, E; Chadarevian, R; Fassnacht, M; Haak, HR; Kerkhofs, TM; Leboulleux, S; Mantero, F; Mueller, HH; Skogseid, B; Terzolo, M, 2013) |
| "Mitotane is the only approved drug for treatment of adrenocortical carcinoma." | 5.17 | Comparison of two mitotane starting dose regimens in patients with advanced adrenocortical carcinoma. ( Allolio, B; Baudin, E; Chadarevian, R; Fassnacht, M; Haak, HR; Kerkhofs, TM; Leboulleux, S; Mantero, F; Mueller, HH; Skogseid, B; Terzolo, M, 2013) |
| "The adrenolytic agent mitotane [o,p'-DDD or 1,1-(o,p'-dichlorodiphenyl)-2, 2-dichloroethane] has been employed in the nonsurgical treatment of patients with adrenal carcinoma for several decades." | 3.69 | A high-pressure liquid chromatographic method for measuring mitotane [1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethane] and its metabolite 1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethene in plasma. ( Andersen, A; Nome, O; Slørdal, L; Vesterhus, L; Warren, DJ, 1995) |
| "Aminoglutethimide was examined only for effects on CYP11A activity and was shown to inhibit pregnenolone formation (20 microM: 61 +/- 4% of control)." | 1.31 | Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. ( Johansson, MK; Lund, BO; Sanderson, JT, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poli, G | 1 |
| Guasti, D | 1 |
| Rapizzi, E | 1 |
| Fucci, R | 1 |
| Canu, L | 1 |
| Bandini, A | 1 |
| Cini, N | 1 |
| Bani, D | 1 |
| Mannelli, M | 1 |
| Luconi, M | 1 |
| Kerkhofs, TM | 1 |
| Baudin, E | 1 |
| Terzolo, M | 1 |
| Allolio, B | 1 |
| Chadarevian, R | 1 |
| Mueller, HH | 1 |
| Skogseid, B | 1 |
| Leboulleux, S | 1 |
| Mantero, F | 1 |
| Haak, HR | 1 |
| Fassnacht, M | 1 |
| Theile, D | 1 |
| Haefeli, WE | 1 |
| Weiss, J | 1 |
| Andersen, A | 1 |
| Warren, DJ | 1 |
| Nome, O | 1 |
| Vesterhus, L | 1 |
| Slørdal, L | 1 |
| Johansson, MK | 1 |
| Sanderson, JT | 1 |
| Lund, BO | 1 |
1 trial available for dichlorodiphenyl dichloroethylene and Adrenal Cortex Neoplasms
| Article | Year |
|---|---|
Comparison of two mitotane starting dose regimens in patients with advanced adrenocortical carcinoma.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Agents, Ho | 2013 |
4 other studies available for dichlorodiphenyl dichloroethylene and Adrenal Cortex Neoplasms
| Article | Year |
|---|---|
Morphofunctional effects of mitotane on mitochondria in human adrenocortical cancer cells.
Topics: Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; Apoptosis; Cell Line, Tumor; Cell Surviva | 2013 |
Effects of adrenolytic mitotane on drug elimination pathways assessed in vitro.
Topics: Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; ATP-Binding Cassette Transporters; Biotra | 2015 |
A high-pressure liquid chromatographic method for measuring mitotane [1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethane] and its metabolite 1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethene in plasma.
Topics: Absorption; Adolescent; Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; Carcinoma; Chroma | 1995 |
Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line.
Topics: Adrenal Cortex Neoplasms; Aminoglutethimide; Carcinoma; Chromatography, High Pressure Liquid; Colfor | 2002 |