Page last updated: 2024-08-17

dichloroacetic acid and Obesity

dichloroacetic acid has been researched along with Obesity in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chuang, DT; Chuang, JL; Gui, WJ; Morlock, LK; Owens, KR; Qi, X; Scherer, PE; Tambar, UK; Tso, SC; Wernstedt-Asterholm, I; Williams, NS; Wu, CY; Wynn, RM1
Ahn, JH; Bae, EJ; Bae, MA; Chi, YI; Choi, WI; Dighe, M; Gim, HE; Jaladi, AK; Jang, YK; Jeon, JH; Jeon, YH; Jung, KY; Kim, M; Lee, D; Lee, GH; Lee, IK; Lee, KM; Lee, S; Lee, T; Liu, KH; Pagire, HS; Pagire, SH; Park, S; Song, JS; Yoo, EK1
Go, Y; Jeon, JH; Jeon, YH; Kang, HJ; Kim, DW; Kim, HE; Kim, JE; Kim, MJ; Kim, YH; Lee, CH; Lee, IK; Lee, JM; Min, BK; Oh, CJ; Park, BY; Park, S; Yoo, EK1
Enser, M; Whittington, FM1
Hayek, A; Woodside, WF2

Other Studies

6 other study(ies) available for dichloroacetic acid and Obesity

ArticleYear
Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocket.
    The Journal of biological chemistry, 2014, Feb-14, Volume: 289, Issue:7

    Topics: Animals; Diabetes Mellitus, Type 2; Drug Delivery Systems; Drug Design; Enzyme Inhibitors; Fatty Liver; HSP90 Heat-Shock Proteins; Humans; Isoenzymes; Isoindoles; Male; Mice; Mice, Obese; Obesity; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Sulfones

2014
Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases.
    Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2

    Topics: Administration, Oral; Animals; Anthraquinones; Binding Sites; Cell Line; Half-Life; Humans; Hypoglycemic Agents; Male; Metabolic Diseases; Mice; Mice, Inbred C57BL; Mice, Obese; Microsomes, Liver; Molecular Docking Simulation; Obesity; Protein Kinase Inhibitors; Protein Kinases; Rats; Structure-Activity Relationship

2019
Therapeutic effect of dichloroacetate against atherosclerosis via hepatic FGF21 induction mediated by acute AMPK activation.
    Experimental & molecular medicine, 2019, 09-30, Volume: 51, Issue:10

    Topics: Adipose Tissue, Brown; AMP-Activated Protein Kinases; Animals; Apolipoproteins E; Atherosclerosis; Cardiovascular Agents; Dichloroacetic Acid; Diet, Western; Dyslipidemias; Energy Metabolism; Enzyme Inhibitors; Fibroblast Growth Factors; Gene Expression Regulation; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Mitochondria; Obesity; Oxygen Consumption; Plaque, Atherosclerotic; PPAR alpha; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA, Messenger; Signal Transduction; Uncoupling Protein 1

2019
The actions of dichloroacetic acid on blood glucose, liver glycogen and fatty acid synthesis in obese-hyperglycaemic (ob/ob) and lean mice.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1983, Volume: 15, Issue:5

    Topics: Acetates; Adipose Tissue; Animals; Blood Glucose; Dichloroacetic Acid; Fatty Acids; Female; Hyperglycemia; Insulin; Lactates; Lactic Acid; Liver Glycogen; Mice; Obesity

1983
Short-term influences of dichloroacetate on genetically hyperlipemic rats.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:2

    Topics: Acetates; Animals; Dichloroacetic Acid; Disease Models, Animal; Fatty Acids, Nonesterified; Glucagon; Hyperlipidemias; Hypoglycemia; Insulin; Ketone Bodies; Obesity; Rats; Triglycerides

1980
Long-term dichloroacetate administration to genetically hyperlipemic rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1981, Volume: 13, Issue:3

    Topics: Acetates; Animals; Dichloroacetic Acid; Disease Models, Animal; Obesity; Rats

1981