dichloroacetic acid has been researched along with Lung Neoplasms in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Azawi, A; Arafat, K; Attoub, S; Nemmar, A; Sulaiman, S; Yasin, J | 1 |
| Chen, F; Chen, X; Huang, Y; She, H | 1 |
| Huang, G; Liu, J; Ma, W; Wang, K; Zhao, X | 1 |
| Bahng, A; Black, A; Britten, CD; Christofk, HR; Crabtree, MJ; Dubinett, SM; Garon, EB; Hong, CS; Hosmer, W; Kabbinavar, F; Kamranpour, N; Michelakis, ED; Patel, C; Pitts, S; Slamon, DJ; von Euw, E | 1 |
| Feinberg, T; Ilouze, M; Lawrence, YR; Peled, N; Shavit, R; Tzur, Y | 1 |
| Dutta, SK; Ghosh, M; Saha, S | 1 |
| Boychuk, IV; Dasyukevich, OI; Kolesnik, DL; Melnikov, OR; Pyaskovskaya, ON; Solyanik, GI; Tarasov, AS | 1 |
| Allen, KT; Chin-Sinex, H; DeLuca, T; Foley, J; Jesseph, JM; Mendonca, MS; Pomerening, JR; Sherer, J; Watkins, JB | 1 |
| Tam, KY; Yang, Z | 1 |
| Borgel, S; Hancock, C; Hollingshead, MG; Newton, DL; Phillips, LR; Stockwin, LH; Wolfe, TL; Yu, SX | 1 |
| Fiebiger, W; Geissler, K; Hamilton, G; Olszewski, U; Ulsperger, E | 1 |
| Martin, NK; Robey, IF | 1 |
1 trial(s) available for dichloroacetic acid and Lung Neoplasms
| Article | Year |
|---|---|
Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dichloroacetic Acid; Docetaxel; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Oxygen Consumption; Taxoids; Treatment Failure | 2014 |
12 other study(ies) available for dichloroacetic acid and Lung Neoplasms
| Article | Year |
|---|---|
Impact of Sodium Dichloroacetate Alone and in Combination Therapies on Lung Tumor Growth and Metastasis.
Topics: A549 Cells; Animals; Cellular Reprogramming; Dichloroacetic Acid; Glycolysis; Humans; Lung Neoplasms; Mice; Neoplasm Metastasis; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Xenograft Model Antitumor Assays | 2021 |
Risk factors and prognostic factors for pulmonary large cell neuroendocrine carcinoma with brain metastasis.
Topics: Brain Neoplasms; Carcinoma, Neuroendocrine; Dichloroacetic Acid; Humans; Lung Neoplasms; Models, Statistical; Nomograms; Prognosis; Reproducibility of Results; Risk Factors; SEER Program | 2023 |
Dichloroacetic acid (DCA) synergizes with the SIRT2 inhibitor Sirtinol and AGK2 to enhance anti-tumor efficacy in non-small cell lung cancer.
Topics: Animals; Benzamides; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dichloroacetic Acid; Drug Synergism; Energy Metabolism; Furans; G1 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; Mice; Mitogen-Activated Protein Kinases; Naphthols; Quinolines; Sirtuin 2 | 2018 |
Mitochondrial induction as a potential radio-sensitizer in lung cancer cells - a short report.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dichloroacetic Acid; Humans; Lung Neoplasms; Mitochondria; Radiation-Sensitizing Agents | 2015 |
A potent tumoricidal co-drug 'Bet-CA'--an ester derivative of betulinic acid and dichloroacetate selectively and synergistically kills cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Betulinic Acid; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dichloroacetic Acid; Disease Models, Animal; Drug Synergism; Esters; Female; Humans; Inhibitory Concentration 50; Lung Neoplasms; Melanoma; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitochondria; NIH 3T3 Cells; Oxidative Stress; Pentacyclic Triterpenes; Reactive Oxygen Species; Triterpenes | 2015 |
Effect of dichloroacetate on Lewis lung carcinoma growth and metastasis.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Dichloroacetic Acid; Drug Screening Assays, Antitumor; Electron Transport Chain Complex Proteins; Lung Neoplasms; Mice, Inbred C57BL; Mitochondria; Neoplasm Transplantation; Tumor Burden | 2015 |
Dichloroacetate alters Warburg metabolism, inhibits cell growth, and increases the X-ray sensitivity of human A549 and H1299 NSC lung cancer cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Proliferation; Comet Assay; Dichloroacetic Acid; DNA Breaks, Double-Stranded; DNA Repair; Glycolysis; Humans; Lung Neoplasms; Radiation Tolerance; Tumor Cells, Cultured; X-Rays | 2015 |
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Humans; Lung Neoplasms; Matrix Metalloproteinases; Mutation; Protein Kinase Inhibitors; Signal Transduction | 2016 |
NTP report on the toxicology studies of dichloroacetic acid (CAS No. 79-43-6) in genetically modified (FVB Tg.AC hemizygous) mice (dermal and drinking water studies) and carcinogenicity studies of dichloroacetic acid in genetically modified [B6.129-Trp53(
Topics: Adenoma; Administration, Cutaneous; Animals; Carcinogenicity Tests; Carcinoma; Dichloroacetic Acid; Female; Genes, ras; Lung Neoplasms; Male; Mice; Mice, Transgenic; Papilloma; Skin Neoplasms; Tumor Suppressor Protein p53; Water Pollutants, Chemical; Water Supply | 2007 |
Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Dose-Response Relationship, Drug; Electron Transport; Glycolysis; HCT116 Cells; HL-60 Cells; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Proteomics; Rabbits; Xenograft Model Antitumor Assays | 2010 |
In vitro cytotoxicity of novel platinum-based drugs and dichloroacetate against lung carcinoid cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytotoxins; Dichloroacetic Acid; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Organoplatinum Compounds; Platinum Compounds | 2011 |
Bicarbonate and dichloroacetate: evaluating pH altering therapies in a mouse model for metastatic breast cancer.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Bicarbonates; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Dichloroacetic Acid; Disease Models, Animal; Female; Humans; Hydrogen-Ion Concentration; Lactates; Lung Neoplasms; Mice; Mice, SCID; Sodium Bicarbonate; Survival Analysis; Tumor Burden; Tumor Microenvironment | 2011 |