dichloroacetic acid has been researched along with Leigh Disease in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katsumi, Y; Morimoto, M; Naito, E; Nishimura, A; Sugimoto, T | 1 |
| Kakimoto, N; Katayama, K; Koga, Y; Matsuishi, T; Naito, E; Povalko, N; Tanaka, M | 1 |
| Fujii, T; Ito, M; Miyajima, T; Okuno, T | 1 |
| Craigen, WJ | 1 |
| Maemoto, T; Niimi, H; Sugita, K; Takanashi, J; Tanabe, Y | 1 |
| Kimura, S; Nezu, A; Ohtuki, N; Takeshita, S; Tanaka, M | 1 |
| Miyamoto, A; Oki, J; Okuno, A; Takahashi, S | 1 |
| Miyabayashi, S; Narisawa, K | 1 |
| Kamoshita, S; Kodama, H; Miyabayashi, S; Okabe, I; Shimoizumi, H | 1 |
9 other study(ies) available for dichloroacetic acid and Leigh Disease
| Article | Year |
|---|---|
Treatment for Leigh syndrome by monitoring dichloroacetate concentration.
Topics: Brain; Dichloroacetic Acid; Disease Progression; Humans; Infant; Leigh Disease; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Monitoring, Physiologic | 2009 |
Beneficial effect of pyruvate therapy on Leigh syndrome due to a novel mutation in PDH E1α gene.
Topics: Alanine; Cells, Cultured; Child, Preschool; Dichloroacetic Acid; Electroencephalography; Fibroblasts; Humans; Lactic Acid; Leigh Disease; Male; Mutation; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Statistics, Nonparametric | 2012 |
Dichloroacetate therapy in Leigh syndrome with a mitochondrial T8993C mutation.
Topics: Brain; Child; Dichloroacetic Acid; DNA, Mitochondrial; Female; Humans; Leigh Disease; Magnetic Resonance Imaging; Point Mutation | 2002 |
Leigh disease with deficiency of lipoamide dehydrogenase: treatment failure with dichloroacetate.
Topics: Acidosis, Lactic; Amino Acids, Branched-Chain; Child, Preschool; Dichloroacetic Acid; Dihydrolipoamide Dehydrogenase; Enzyme Activation; Fatal Outcome; Female; Humans; Infant; Isoleucine; Lactates; Lactic Acid; Leigh Disease; Pyruvate Dehydrogenase Complex; Treatment Failure | 1996 |
Dichloroacetate treatment in Leigh syndrome caused by mitochondrial DNA mutation.
Topics: Aspartic Acid; Brain; Creatine; Dichloroacetic Acid; DNA, Mitochondrial; Female; Humans; Infant; Lactates; Leigh Disease; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mutation | 1997 |
Clinical and radiologic improvements in mitochondrial encephalomyelopathy following sodium dichloroacetate therapy.
Topics: Brain; Central Nervous System Diseases; Child; Dichloroacetic Acid; Female; Humans; Infant; Leigh Disease; Magnetic Resonance Imaging; Male; Myelin Sheath; Spinal Cord | 1997 |
Proton magnetic resonance spectroscopy to study the metabolic changes in the brain of a patient with Leigh syndrome.
Topics: Brain; Dichloroacetic Acid; DNA, Mitochondrial; Humans; Infant; Lactates; Leigh Disease; Magnetic Resonance Spectroscopy; Male; Point Mutation; Psychomotor Performance; Pyruvates; Thiamine | 1999 |
[Clinical and biochemical approach to mitochondrial cytopathy--pyruvate dehydrogenase complex deficiency].
Topics: Child, Preschool; Dichloroacetic Acid; Humans; Infant; Infant, Newborn; Leigh Disease; Microscopy, Electron; Mitochondria, Muscle; Muscles; Prenatal Diagnosis; Pyruvate Dehydrogenase Complex Deficiency Disease | 1987 |
Treatment of lactic acidosis: effects of dichloroacetate on lactate and pyruvate levels in the cerebrospinal fluid.
Topics: Acetates; Acidosis; Administration, Oral; Dichloroacetic Acid; Fibroblasts; Humans; Infant; Lactates; Leigh Disease; Male; Pyruvates | 1986 |