Page last updated: 2024-08-17

dichloroacetic acid and Glioma

dichloroacetic acid has been researched along with Glioma in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Chang, C; Chornenkyy, Y; Hawkins, C; Joshi, S; Liu, J; Ryall, S; Shen, H; Siddaway, R; Tsoli, M; Yu, M; Ziegler, DS1
Cook, KM; Gee, HE; Hau, E; McKelvey, KJ; Shen, H1
Kolesnik, DL; Prokhorova, IV; Pyaskovskaya, ON; Solyanik, GI1
Boichuk, IV; Kolesnik, DL; Pyaskovskaya, ON; Solyanik, GI1
Fedorchuk, AG; Gorbik, GV; Kolesnik, DL; Prokhorova, IV; Pyaskovskaya, ON; Solyanik, GI1
Brodie, C; Brodie, Z; Cazacu, S; Finniss, S; Jiang, W; Mikkelsen, T; Poisson, L; Shackelford, DB; Xiang, C1
Bahut, M; Bonnamain, V; Gueguen, N; Guette, C; Lalier, L; Morfouace, M; Naveilhan, P; Oliver, L; Reynier, P; Vallette, FM1
Hurd, RE; Jang, T; Josan, S; Mayer, D; Merchant, M; Park, JM; Recht, LD; Spielman, DM; Yen, YF1

Reviews

1 review(s) available for dichloroacetic acid and Glioma

ArticleYear
Targeting Glucose Metabolism of Cancer Cells with Dichloroacetate to Radiosensitize High-Grade Gliomas.
    International journal of molecular sciences, 2021, Jul-06, Volume: 22, Issue:14

    Topics: Animals; Cell Proliferation; Dichloroacetic Acid; Glioma; Glucose; Glycolysis; Humans; Mitochondria; Oxidative Phosphorylation; Radiation Tolerance

2021

Other Studies

7 other study(ies) available for dichloroacetic acid and Glioma

ArticleYear
Targeting reduced mitochondrial DNA quantity as a therapeutic approach in pediatric high-grade gliomas.
    Neuro-oncology, 2020, 01-11, Volume: 22, Issue:1

    Topics: Aminoimidazole Carboxamide; Animals; Brain Neoplasms; Child; Dichloroacetic Acid; DNA, Mitochondrial; Energy Metabolism; Gene Dosage; Glioma; Glycolysis; Humans; Mice; Ribonucleotides; Xenograft Model Antitumor Assays

2020
Influence of metformin, sodium dichloroacetate and their combination on the hematological and biochemical blood parameters of rats with gliomas C6.
    Experimental oncology, 2018, Volume: 40, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dichloroacetic Acid; Female; Glioma; Hematology; Humans; Metformin; Rats

2018
Hypoxia enhances antitumor activity of dichloroacetate.
    Experimental oncology, 2014, Volume: 36, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dichloroacetic Acid; Glioma; Humans; Hyperoxia; Hypoxia; Inhibitory Concentration 50; Lactic Acid; Necrosis; Neoplasms; Reactive Oxygen Species

2014
Effectiveness of sodium dichloroacetate against glioma C6 depends on administration schedule and dosage.
    Experimental oncology, 2016, Volume: 38, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Drug Administration Schedule; Female; Glioma; Mitochondria; Oxygen; Rats, Wistar

2016
Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma.
    Oncotarget, 2016, Aug-30, Volume: 7, Issue:35

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Proliferation; Dichloroacetic Acid; Drug Repositioning; Gene Silencing; Glioblastoma; Glioma; HMGA2 Protein; Humans; Hypoglycemic Agents; Lentivirus; Mice; Mice, Nude; MicroRNAs; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neoplastic Stem Cells; Phenformin; RNA, Long Noncoding

2016
Comparison of spheroids formed by rat glioma stem cells and neural stem cells reveals differences in glucose metabolism and promising therapeutic applications.
    The Journal of biological chemistry, 2012, Sep-28, Volume: 287, Issue:40

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Dichloroacetic Acid; Drug Design; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Glucose; Glycolysis; Neoplastic Stem Cells; Neural Stem Cells; Phosphorylation; Proteomics; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spheroids, Cellular; Tumor Cells, Cultured

2012
Metabolic response of glioma to dichloroacetate measured in vivo by hyperpolarized (13)C magnetic resonance spectroscopic imaging.
    Neuro-oncology, 2013, Volume: 15, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Brain; Brain Neoplasms; Carbon Radioisotopes; Dichloroacetic Acid; Glioma; Magnetic Resonance Imaging; Male; Mitochondria; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvates; Rats; Rats, Wistar; Tumor Cells, Cultured

2013