dichloroacetic acid has been researched along with Carcinoma, Non-Small Cell Lung in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, G; Liu, J; Ma, W; Wang, K; Zhao, X | 1 |
| Huang, WD; Shen, SY; Zheng, MF | 1 |
| Bahng, A; Black, A; Britten, CD; Christofk, HR; Crabtree, MJ; Dubinett, SM; Garon, EB; Hong, CS; Hosmer, W; Kabbinavar, F; Kamranpour, N; Michelakis, ED; Patel, C; Pitts, S; Slamon, DJ; von Euw, E | 1 |
| Feinberg, T; Ilouze, M; Lawrence, YR; Peled, N; Shavit, R; Tzur, Y | 1 |
| Allen, KT; Chin-Sinex, H; DeLuca, T; Foley, J; Jesseph, JM; Mendonca, MS; Pomerening, JR; Sherer, J; Watkins, JB | 1 |
| Tam, KY; Yang, Z | 1 |
1 trial(s) available for dichloroacetic acid and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dichloroacetic Acid; Docetaxel; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Oxygen Consumption; Taxoids; Treatment Failure | 2014 |
5 other study(ies) available for dichloroacetic acid and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Dichloroacetic acid (DCA) synergizes with the SIRT2 inhibitor Sirtinol and AGK2 to enhance anti-tumor efficacy in non-small cell lung cancer.
Topics: Animals; Benzamides; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dichloroacetic Acid; Drug Synergism; Energy Metabolism; Furans; G1 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; Mice; Mitogen-Activated Protein Kinases; Naphthols; Quinolines; Sirtuin 2 | 2018 |
DCA increases the antitumor effects of capecitabine in a mouse B16 melanoma allograft and a human non-small cell lung cancer A549 xenograft.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Deoxycytidine; Dichloroacetic Acid; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Humans; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Proteins; Prodrugs; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Random Allocation; Thymidine Phosphorylase; Xenograft Model Antitumor Assays | 2013 |
Mitochondrial induction as a potential radio-sensitizer in lung cancer cells - a short report.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dichloroacetic Acid; Humans; Lung Neoplasms; Mitochondria; Radiation-Sensitizing Agents | 2015 |
Dichloroacetate alters Warburg metabolism, inhibits cell growth, and increases the X-ray sensitivity of human A549 and H1299 NSC lung cancer cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Proliferation; Comet Assay; Dichloroacetic Acid; DNA Breaks, Double-Stranded; DNA Repair; Glycolysis; Humans; Lung Neoplasms; Radiation Tolerance; Tumor Cells, Cultured; X-Rays | 2015 |
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Humans; Lung Neoplasms; Matrix Metalloproteinases; Mutation; Protein Kinase Inhibitors; Signal Transduction | 2016 |