Compounds > dichloroacetic acid
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dichloroacetic acid and Blood Poisoning

dichloroacetic acid has been researched along with Blood Poisoning in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Angus, DC; Bakalov, V; Chang, CH; Deshpande, R; Kaynar, AM; Le Moyec, L; Maloy, AL; Reyes-Uribe, L; Shapiro, SD; Wendell, SG1
Buechler, N; Furdui, C; Key, CC; Long, D; Mainali, R; Martinez, J; McCall, CE; Parks, JS; Quillen, E; Quinn, MA; Stacpoole, PW; Zabalawi, M; Zhu, X1
Arts, RJW; Buechler, NL; Liu, T; Long, DL; Martin, A; McCall, CE; Netea, M; Stacpoole, PW; Vachharajani, V; Yoza, BK; Zabalawi, M1
L'Her, E; Sebert, P1
Jahoor, F; Lang, CH; Shangraw, RE; Wolfe, RR1
DeMaria, EJ; Gore, DC; Hibbert, JM; Jahoor, F1
Hazen, S; Vary, TC1
Arnon, S; Dolfin, T; Elpeleg, O; Litmanovits, I; Regev, R1
Placko, R; Siegel, JH; Vary, TC1
Bagby, GJ; Blakesley, HL; Lang, CH; Spitzer, JJ1

Other Studies

10 other study(ies) available for dichloroacetic acid and Blood Poisoning

ArticleYear
Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Acetyl Coenzyme A; Animals; Citric Acid Cycle; Dichloroacetic Acid; Drosophila melanogaster; Glycolysis; Inflammation; Lactic Acid; Longevity; Oxidative Phosphorylation; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Sepsis

2020
Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction.
    eLife, 2021, 02-22, Volume: 10

    Topics: Animals; Citric Acid Cycle; Dichloroacetic Acid; Disease Models, Animal; Energy Metabolism; Hepatocytes; Male; Mice; Mice, Inbred C57BL; Mitochondria; Oxidation-Reduction; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Sepsis

2021
Pyruvate dehydrogenase complex stimulation promotes immunometabolic homeostasis and sepsis survival.
    JCI insight, 2018, 08-09, Volume: 3, Issue:15

    Topics: Animals; Cells, Cultured; Dichloroacetic Acid; Disease Models, Animal; Drug Evaluation, Preclinical; Energy Metabolism; Homeostasis; Humans; Kaplan-Meier Estimate; Male; Mice; Mitochondria; Monocytes; Primary Cell Culture; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Sepsis; Signal Transduction; Treatment Outcome

2018
Effects of dichloroacetate and ubiquinone infusions on glycolysis activity and thermal sensitivity during sepsis.
    The Journal of laboratory and clinical medicine, 2004, Volume: 143, Issue:6

    Topics: Animals; Body Temperature Regulation; Coenzymes; Dichloroacetic Acid; Electron Transport Complex III; Enzyme Activation; Glucose; Glycolysis; Infusions, Intravenous; Lactic Acid; Male; Mitochondria; Muscle, Skeletal; Pyruvate Dehydrogenase Complex; Rats; Rats, Sprague-Dawley; Sepsis; Ubiquinone

2004
Pyruvate dehydrogenase inactivity is not responsible for sepsis-induced insulin resistance.
    Critical care medicine, 1996, Volume: 24, Issue:4

    Topics: Adult; Animals; APACHE; Dichloroacetic Acid; Drug Evaluation; Drug Evaluation, Preclinical; Enzyme Activation; Escherichia coli Infections; Glucose; Gram-Negative Bacterial Infections; Humans; Insulin Resistance; Male; Middle Aged; Prospective Studies; Pyruvate Dehydrogenase Complex; Rats; Rats, Sprague-Dawley; Sepsis

1996
Lactic acidosis during sepsis is related to increased pyruvate production, not deficits in tissue oxygen availability.
    Annals of surgery, 1996, Volume: 224, Issue:1

    Topics: Acidosis, Lactic; Adult; Blood Glucose; Breath Tests; Calorimetry, Indirect; Dichloroacetic Acid; Female; Humans; Lactates; Middle Aged; Oxygen; Oxygen Consumption; Pyruvates; Sepsis; Time Factors

1996
Sepsis alters pyruvate dehydrogenase kinase activity in skeletal muscle.
    Molecular and cellular biochemistry, 1999, Volume: 198, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Bacterial Infections; Chromatography, Gel; Dichloroacetic Acid; Mitochondria, Muscle; Muscle, Skeletal; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Rats; Sepsis

1999
Dichloroacetate treatment for severe refractory metabolic acidosis during neonatal sepsis.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:2

    Topics: Acidosis, Lactic; Dichloroacetic Acid; Humans; Infant, Newborn; Sepsis; Sodium Bicarbonate; Streptococcal Infections

2001
Pharmacologic modulation of increased release of gluconeogenic precursors from extra-splanchnic organs in sepsis.
    Circulatory shock, 1989, Volume: 29, Issue:1

    Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Cycloserine; Dichloroacetic Acid; Gluconeogenesis; Glutamate-Ammonia Ligase; Glutamine; Hepatectomy; Intestine, Small; Lactates; Lactic Acid; Liver; Male; Methionine Sulfoximine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; Sepsis

1989
Glucose kinetics and pyruvate dehydrogenase activity in septic rats treated with dichloroacetate.
    Circulatory shock, 1987, Volume: 23, Issue:2

    Topics: Acetates; Animals; Blood Glucose; Dichloroacetic Acid; Escherichia coli Infections; Fever; Hemodynamics; Injections, Intravenous; Insulin; Liver; Male; Muscles; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; Sepsis

1987