Compounds > dichloroacetic acid
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dichloroacetic acid and B-Cell Chronic Lymphocytic Leukemia

dichloroacetic acid has been researched along with B-Cell Chronic Lymphocytic Leukemia in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agnoletto, C; Brunelli, L; Casciano, F; Celeghini, C; Cuneo, A; Melloni, E; Rigolin, GM; Rimondi, E; Secchiero, P; Zauli, G1
Agnoletto, C; Brunelli, L; Casciano, F; Cuneo, A; Melloni, E; Pastorelli, R; Rigolin, GM; Rimondi, E; Secchiero, P; Zauli, G1
Bertolasi, V; Casciano, F; Gilli, P; Melloni, E; Rigolin, GM; Rimondi, E; Secchiero, P; Voltan, R; Zauli, G1

Other Studies

3 other study(ies) available for dichloroacetic acid and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3.
    Oncotarget, 2014, Jun-30, Volume: 5, Issue:12

    Topics: Aged; Aged, 80 and over; Dichloroacetic Acid; Drug Synergism; Female; Humans; Imidazoles; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Piperazines; Tumor Suppressor Protein p53

2014
The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathway.
    Oncotarget, 2015, Feb-10, Volume: 6, Issue:4

    Topics: Aged; Blotting, Western; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Dichloroacetic Acid; Female; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Models, Genetic; Mutation; Nuclear Factor 90 Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tumor Suppressor Protein p53

2015
Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1.
    Oncotarget, 2016, Apr-05, Volume: 7, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Death; Cell Line, Tumor; Dichloroacetic Acid; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Metformin; Myeloid Cell Leukemia Sequence 1 Protein

2016