dichloroacetic acid has been researched along with Astrocytoma, Grade IV in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (88.24) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Alonso, MM; Balnytė, I; Damanskienė, E; Lesauskaitė, V; Stakišaitis, D; Valančiūtė, A | 1 |
| Albayrak, G; Dere, UA; Emmez, H; Konac, E | 1 |
| D'Agostino, DP; Koutnik, AP; Poff, AM; Ward, NP | 1 |
| Abdel-Aziz, W; Abdel-Latif, HM; Aboonq, MS; Ahmed, NS; Almaramhy, HH; Ayat, M; Baghdadi, H; El Sayed, SM; El-Sawy, SA; Elshazley, M; Ibrahim, W; Mahmoud, AA | 1 |
| Asuthkar, S; Bhasin, A; Tsung, AJ; Velpula, KK | 1 |
| Azadi, J; Bow, H; Brem, H; Hutt-Cabezas, M; Hwang, L; Joshi, A; Mangraviti, A; Martin, KL; Rudek, MA; Tyler, BM; Wicks, RT; Zhang, I; Zhao, M | 1 |
| Takahashi, H; Takahashi, M; Watari, E | 1 |
| Chen, A; Jiang, A; Li, C; Meng, G; Su, L; Wei, J; Xia, M; Xu, C; Yu, D | 1 |
| Chung, SA; Decollogne, S; Dilda, PJ; Hau, E; Hogg, PJ; Luk, PP; McDonald, KL; Shen, H | 1 |
| Blough, M; Cai, L; Cairncross, JG; Chaumeil, MM; Eriksson, P; Izquierdo-Garcia, JL; Luchman, HA; Phillips, JJ; Pieper, RO; Radoul, M; Ronen, SM; Viswanath, P; Weiss, S | 1 |
| Dilda, PJ; Hau, E; Joshi, S; McDonald, KL; Shen, H | 1 |
| Asuthkar, S; Guda, MR; Tsung, AJ; Velpula, KK; Yuen, CA | 1 |
| Brodie, C; Brodie, Z; Cazacu, S; Finniss, S; Jiang, W; Mikkelsen, T; Poisson, L; Shackelford, DB; Xiang, C | 1 |
| Vander Heiden, MG | 1 |
| Abdulkarim, B; Dromparis, P; Fulton, D; Gammer, TL; Haromy, A; Mackey, JR; Maguire, C; McMurtry, MS; Michelakis, ED; Niven, E; Petruk, KC; Sutendra, G; Webster, L | 1 |
| Bahut, M; Bonnamain, V; Gueguen, N; Guette, C; Lalier, L; Morfouace, M; Naveilhan, P; Oliver, L; Reynier, P; Vallette, FM | 1 |
| Kessler, W; Kioschis, P; Schneckenburger, H; Wagner, M; Weber, P | 1 |
1 review(s) available for dichloroacetic acid and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Cancer stem cell molecular reprogramming of the Warburg effect in glioblastomas: a new target gleaned from an old concept.
Topics: Angiogenesis Inhibitors; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Hypoxia; Cell Self Renewal; Cellular Reprogramming; Dichloroacetic Acid; Drug Resistance, Neoplasm; Glioblastoma; Glycolysis; Humans; Molecular Targeted Therapy; Neoplasm Proteins; Neoplastic Stem Cells; Oxidative Phosphorylation; Signal Transduction; Up-Regulation | 2016 |
16 other study(ies) available for dichloroacetic acid and Astrocytoma, Grade IV
| Article | Year |
|---|---|
The Comparative Experimental Study of Sodium and Magnesium Dichloroacetate Effects on Pediatric PBT24 and SF8628 Cell Glioblastoma Tumors Using a Chicken Embryo Chorioallantoic Membrane Model and on Cells In Vitro.
Topics: Acetates; Animals; Chick Embryo; Chickens; Chorioallantoic Membrane; Dichloroacetic Acid; Glioblastoma; Humans; Magnesium; Monocarboxylic Acid Transporters; Proliferating Cell Nuclear Antigen; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Sodium; Solute Carrier Family 12, Member 2; Survivin; Tumor Suppressor Protein p53 | 2022 |
Targeting Cancer Cell Metabolism with Metformin, Dichloroacetate and Memantine in Glioblastoma (GBM).
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Dopamine Agents; Dose-Response Relationship, Drug; Glioblastoma; Humans; Hypoglycemic Agents; Memantine; Metformin; Proto-Oncogene Proteins c-bcl-2 | 2021 |
Complex I inhibition augments dichloroacetate cytotoxicity through enhancing oxidative stress in VM-M3 glioblastoma cells.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Electron Transport Complex I; Glioblastoma; Membrane Potential, Mitochondrial; Metformin; Mice; Oxidative Stress; Rotenone; Superoxides | 2017 |
Dichloroacetate is an antimetabolite that antagonizes acetate and deprives cancer cells from its benefits: A novel evidence-based medical hypothesis.
Topics: Acetates; Acetyl Coenzyme A; Animals; Antineoplastic Agents; Brain Neoplasms; Chlorides; Dichloroacetic Acid; Evidence-Based Medicine; Glioblastoma; Heart; Humans; Ketones; Lactic Acid; Models, Theoretical; Neoplasms; Oxygen; Perfusion; Rats | 2019 |
Combined targeting of PDK1 and EGFR triggers regression of glioblastoma by reversing the Warburg effect.
Topics: Animals; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Transformation, Neoplastic; Dichloroacetic Acid; ErbB Receptors; Female; Glioblastoma; Humans; Mice; Mice, Nude; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Signal Transduction | 2013 |
Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.
Topics: Absorbable Implants; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Dacarbazine; Dichloroacetic Acid; Drug Administration Routes; Drug Combinations; Drug Delivery Systems; Female; Glioblastoma; Glycolysis; Humans; Kaplan-Meier Estimate; Polymers; Pyruvates; Rats; Rats, Inbred F344; Temozolomide | 2015 |
Dichloroacetate induces cell cycle arrest in human glioblastoma cells persistently infected with measles virus: a way for controlling viral persistent infection.
Topics: Blotting, Western; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dichloroacetic Acid; Glioblastoma; Humans; Measles virus; Mitochondria; Nuclear Proteins; Nucleocapsid Proteins | 2015 |
Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma.
Topics: Aerobiosis; Animals; Brain Neoplasms; Cell Line, Tumor; Dichloroacetic Acid; Glioblastoma; Glycolysis; Humans; Male; Measles virus; Mice; Mice, Inbred BALB C; Mice, Nude; Oncolytic Virotherapy; Random Allocation; Virus Replication; Xenograft Model Antitumor Assays | 2015 |
Dual-targeting of aberrant glucose metabolism in glioblastoma.
Topics: Arsenicals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dichloroacetic Acid; G2 Phase Cell Cycle Checkpoints; Gene Expression; Glioblastoma; Glucose; Humans; Membrane Potential, Mitochondrial; Mitochondria; Multidrug Resistance-Associated Proteins; Oxidative Stress; Reactive Oxygen Species | 2015 |
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
Topics: Astrocytes; Cell Line, Tumor; Cell Proliferation; Dichloroacetic Acid; Down-Regulation; Glioblastoma; Glutamic Acid; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Mutation; Pyruvate Dehydrogenase Complex; Pyruvates | 2015 |
Sensitization of Glioblastoma Cells to Irradiation by Modulating the Glucose Metabolism.
Topics: Animals; Carbohydrate Metabolism; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Disease Models, Animal; Female; Glioblastoma; Glucose; Glycolysis; Mice; Mitochondria; Oxidative Phosphorylation; Phenotype; Radiation Tolerance; Radiotherapy; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2015 |
Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Proliferation; Dichloroacetic Acid; Drug Repositioning; Gene Silencing; Glioblastoma; Glioma; HMGA2 Protein; Humans; Hypoglycemic Agents; Lentivirus; Mice; Mice, Nude; MicroRNAs; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neoplastic Stem Cells; Phenformin; RNA, Long Noncoding | 2016 |
Targeting cell metabolism in cancer patients.
Topics: Brain Neoplasms; Dichloroacetic Acid; Glioblastoma; Glucose; Humans; Mitochondria; Pyruvate Dehydrogenase Complex | 2010 |
Metabolic modulation of glioblastoma with dichloroacetate.
Topics: Adult; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dichloroacetic Acid; Female; Glioblastoma; Humans; In Vitro Techniques; Male; Membrane Potential, Mitochondrial; Middle Aged; Mitochondria; Neoplastic Stem Cells; Neovascularization, Pathologic; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Reactive Oxygen Species | 2010 |
Comparison of spheroids formed by rat glioma stem cells and neural stem cells reveals differences in glucose metabolism and promising therapeutic applications.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Dichloroacetic Acid; Drug Design; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Glucose; Glycolysis; Neoplastic Stem Cells; Neural Stem Cells; Phosphorylation; Proteomics; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spheroids, Cellular; Tumor Cells, Cultured | 2012 |
Tumor cell differentiation by label-free fluorescence microscopy.
Topics: Cell Differentiation; Cell Line, Tumor; Dichloroacetic Acid; Fluorescent Dyes; Glioblastoma; Humans; Mitochondria; Principal Component Analysis; Rotenone; Spectrometry, Fluorescence; Transcriptional Activation; Tumor Suppressor Proteins | 2012 |