Page last updated: 2024-10-26

dibutyl phthalate and Testicular Diseases

dibutyl phthalate has been researched along with Testicular Diseases in 13 studies

Dibutyl Phthalate: A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
dibutyl phthalate : A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans.

Testicular Diseases: Pathological processes of the TESTIS.

Research Excerpts

ExcerptRelevanceReference
" Hyperthyroidism was induced in pubertal male rats by intraperitoneal injection of triiodothyronine (T3, 10 microg/kg body weight) for 30 days."3.74Effect of di(n-butyl) phthalate on testicular oxidative damage and antioxidant enzymes in hyperthyroid rats. ( Ahn, MY; Han, SY; Hong, JH; Kang, TS; Kim, HJ; Kim, HS; Kim, IY; Lee, BM; Lee, E; Park, KL, 2007)
"The objective of this study was to determine the susceptible days for the adverse effects of di-n-butyl phthalate (DBP) on development of reproductive system in male offspring following maternal administration on successive 3-day period during late pregnancy."1.31Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy. ( Ema, M; Kawashima, K; Miyawaki, E, 2000)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's4 (30.77)29.6817
2010's6 (46.15)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Willson, CJ1
van den Driesche, S4
Kilcoyne, KR1
Wagner, I1
Rebourcet, D1
Boyle, A1
Mitchell, R1
McKinnell, C1
Macpherson, S3
Donat, R1
Shukla, CJ1
Jorgensen, A1
Meyts, ER1
Skakkebaek, NE1
Sharpe, RM5
Lara, NLM1
França, LR1
Moody, S1
Goh, H1
Bielanowicz, A1
Rippon, P1
Loveland, KL1
Itman, C1
Macleod, DJ1
Welsh, M1
Fisken, M1
Scott, HM1
Hutchison, GR1
Drake, AJ2
Zhou, D1
Wang, H1
Zhang, J1
Kolovos, P1
Platts, S1
Fisher, JS1
Marchetti, N1
Farombi, EO1
Abarikwu, SO1
Adedara, IA1
Oyeyemi, MO1
Lee, E1
Ahn, MY1
Kim, HJ1
Kim, IY1
Han, SY1
Kang, TS1
Hong, JH1
Park, KL1
Lee, BM1
Kim, HS1
Ema, M1
Miyawaki, E1
Kawashima, K1
Srivastava, SP1
Srivastava, S1
Saxena, DK1
Chandra, SV1
Seth, PK1
Fukuoka, M1
Zhou, Y1
Tanaka, A1
Ikemoto, I1
Machida, T1

Other Studies

13 other studies available for dibutyl phthalate and Testicular Diseases

ArticleYear
Phthalate Toxicity in Rats and Its Relation to Testicular Dysgenesis Syndrome in Humans.
    Toxicologic pathology, 2021, Volume: 49, Issue:8

    Topics: Animals; Dibutyl Phthalate; Gonadal Dysgenesis; Humans; Male; Phthalic Acids; Rats; Testicular Disea

2021
Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window.
    JCI insight, 2017, 03-23, Volume: 2, Issue:6

    Topics: Animals; Dibutyl Phthalate; Disease Models, Animal; Female; Gonadal Dysgenesis; Humans; Male; Matern

2017
Dibutyl phthalate induced testicular dysgenesis originates after seminiferous cord formation in rats.
    Scientific reports, 2017, 05-31, Volume: 7, Issue:1

    Topics: Animals; Dibutyl Phthalate; Disease Models, Animal; Female; Fetus; Gonadal Dysgenesis; Humans; Leydi

2017
Prepubertal mouse testis growth and maturation and androgen production are acutely sensitive to di-n-butyl phthalate.
    Endocrinology, 2013, Volume: 154, Issue:9

    Topics: Androgens; Animals; Cell Proliferation; Dibutyl Phthalate; Dose-Response Relationship, Drug; Endocri

2013
Androgen action in the masculinization programming window and development of male reproductive organs.
    International journal of andrology, 2010, Volume: 33, Issue:2

    Topics: Androgen Antagonists; Androgens; Animals; Animals, Newborn; Dibutyl Phthalate; Female; Flutamide; Ge

2010
Di-n-butyl phthalate (DBP) exposure induces oxidative stress in epididymis of adult rats.
    Toxicology and industrial health, 2011, Volume: 27, Issue:1

    Topics: alpha-Glucosidases; Animals; Dibutyl Phthalate; Epididymis; Male; Malondialdehyde; Oxidative Stress;

2011
Inter-relationship between testicular dysgenesis and Leydig cell function in the masculinization programming window in the rat.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Animals; Animals, Newborn; Dibutyl Phthalate; Embryo, Mammalian; Female; Fetus; Gonadal Dysgenesis;

2012
Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate.
    Human reproduction (Oxford, England), 2003, Volume: 18, Issue:7

    Topics: Age Factors; Animals; Body Weight; Dibutyl Phthalate; Disease Models, Animal; Female; Humans; Hyperp

2003
Curcumin and kolaviron ameliorate di-n-butylphthalate-induced testicular damage in rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:1

    Topics: Animals; Antineoplastic Agents; Chemoprevention; Curcuma; Curcumin; Dibutyl Phthalate; Environmental

2007
Effect of di(n-butyl) phthalate on testicular oxidative damage and antioxidant enzymes in hyperthyroid rats.
    Environmental toxicology, 2007, Volume: 22, Issue:3

    Topics: Animals; Catalase; Deoxyguanosine; Dibutyl Phthalate; Enzymes; Glutathione Peroxidase; Hyperthyroidi

2007
Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy.
    Toxicology letters, 2000, Jan-05, Volume: 111, Issue:3

    Topics: Animals; Body Weight; Cryptorchidism; Dibutyl Phthalate; Embryonic and Fetal Development; Female; Ma

2000
Testicular effects of di-n-butyl phthalate (DBP): biochemical and histopathological alterations.
    Archives of toxicology, 1990, Volume: 64, Issue:2

    Topics: Animals; Dibutyl Phthalate; Dose-Response Relationship, Drug; Male; Phthalic Acids; Rats; Rats, Inbr

1990
Mechanism of testicular atrophy induced by di-n-butyl phthalate in rats. Part 2. The effects on some testicular enzymes.
    Journal of applied toxicology : JAT, 1990, Volume: 10, Issue:4

    Topics: Animals; Atrophy; Cell Survival; Chromatography, Gas; Dibutyl Phthalate; Fructose; Germ Cells; Gluco

1990