Page last updated: 2024-10-26

dibutyl phthalate and Insulin Resistance

dibutyl phthalate has been researched along with Insulin Resistance in 4 studies

Dibutyl Phthalate: A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
dibutyl phthalate : A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans.

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
"Dibutyl phthalate is an endocrine disruptor used in a wide range of industrial and agriculture applications."1.62Effects of Subacute Exposure of Dibutyl Phthalate on the Homeostatic Model Assessment, Thyroid Function, and Redox Status in Rats. ( Khan, AR; Khan, S; Majeed, KA; Rehman, H; Saeed, AA; Tahir, MS; Yousaf, MS, 2021)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Hsia, TI1
Huang, PC1
Chen, HC1
Lo, YC1
Chang, WT1
Jou, YY1
Huang, HB1
Majeed, KA1
Yousaf, MS1
Tahir, MS1
Khan, AR1
Khan, S1
Saeed, AA1
Rehman, H1
Deng, T1
Zhang, Y1
Wu, Y1
Ma, P1
Duan, J1
Qin, W1
Yang, X1
Chen, M1
Kim, JH1
Park, HY1
Bae, S1
Lim, YH1
Hong, YC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Associations of Exposure to Phthalates With Insulin Resistance and Epigenetic Change[NCT02284477]60 participants (Anticipated)Interventional2015-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for dibutyl phthalate and Insulin Resistance

ArticleYear
Relationships among phthalate exposure, oxidative stress, and insulin resistance in young military soldiers: A cumulative risk assessment and mediation approach.
    Environment international, 2022, Volume: 165

    Topics: Biomarkers; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Environmental Polluta

2022
Effects of Subacute Exposure of Dibutyl Phthalate on the Homeostatic Model Assessment, Thyroid Function, and Redox Status in Rats.
    BioMed research international, 2021, Volume: 2021

    Topics: Animals; Dibutyl Phthalate; Female; Glucose Tolerance Test; Homeostasis; Hyperglycemia; Insulin Resi

2021
Dibutyl phthalate exposure aggravates type 2 diabetes by disrupting the insulin-mediated PI3K/AKT signaling pathway.
    Toxicology letters, 2018, Jun-15, Volume: 290

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Dibutyl Phthalate; Indoles; Insulin;

2018
Diethylhexyl phthalates is associated with insulin resistance via oxidative stress in the elderly: a panel study.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Aged; Aged, 80 and over; Aging; Blood Glucose; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmen

2013