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dibutyl phthalate and Inflammation

dibutyl phthalate has been researched along with Inflammation in 13 studies

Dibutyl Phthalate: A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
dibutyl phthalate : A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
" Although there is growing evidence supporting a link between DBP exposure and allergic airway inflammation, there is less information concerned with whether the ferroptosis pathway is involved in DBP-aggravated allergic asthma in ovalbumin (OVA)-sensitized mice."8.31Ferroptosis participates in dibutyl phthalate-aggravated allergic asthma in ovalbumin-sensitized mice. ( Chen, Y; Li, Y; Ma, N; Ma, P; Peng, Q; Wei, Y; Wu, Y; Yan, B; Yang, X; Zhang, Y, 2023)
"These results revealed that bisphenol and dibutyl phthalate exposure caused oxidative stress and inflammation in the heart through Nrf2/NF-κB signaling pathway while oral administration of rutin prevents these effects via upregulation of Nrf2 and suppression of NF-κB signaling pathway."8.02Rutin prevents cardiac oxidative stress and inflammation induced by bisphenol A and dibutyl phthalate exposure via NRF-2/NF-κB pathway. ( Alabi, BA; Fatokun, BP; Michael, OS; Ojo, AO; Oluranti, OI, 2021)
" Although there is growing evidence supporting a link between DBP exposure and allergic airway inflammation, there is less information concerned with whether the ferroptosis pathway is involved in DBP-aggravated allergic asthma in ovalbumin (OVA)-sensitized mice."4.31Ferroptosis participates in dibutyl phthalate-aggravated allergic asthma in ovalbumin-sensitized mice. ( Chen, Y; Li, Y; Ma, N; Ma, P; Peng, Q; Wei, Y; Wu, Y; Yan, B; Yang, X; Zhang, Y, 2023)
"These results revealed that bisphenol and dibutyl phthalate exposure caused oxidative stress and inflammation in the heart through Nrf2/NF-κB signaling pathway while oral administration of rutin prevents these effects via upregulation of Nrf2 and suppression of NF-κB signaling pathway."4.02Rutin prevents cardiac oxidative stress and inflammation induced by bisphenol A and dibutyl phthalate exposure via NRF-2/NF-κB pathway. ( Alabi, BA; Fatokun, BP; Michael, OS; Ojo, AO; Oluranti, OI, 2021)
"Testicular inflammation is positively related to decline in male reproductive function."1.56Exposure of DBP in gestation induces inflammation of testicular Sertoli cells in progeny by activating NLRP3 inflammasomes. ( Ding, J; Han, X; Li, D; Ma, T; Meng, X; Wu, J; Yan, M; Zhou, Y, 2020)
"Dibutyl phthalate (DBP) is a type of phthalate, found in high concentrations in indoor air, which appears to have a high inflammatory potential."1.48Dibutyl phthalate modulates phenotype of granulocytes in human blood in response to inflammatory stimuli. ( Bølling, AK; Carlsten, C; Huff, RD; Maestre-Batlle, D; Pena, OM; Randhawa, A, 2018)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (30.77)24.3611
2020's9 (69.23)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Alsubaie, AM1
Arita, Y1
Atwater, M1
Mahfuz, A1
Peltier, MR1
Ahmad, S1
Sharma, S1
Afjal, MA1
Habib, H1
Akhter, J1
Goswami, P1
Parvez, S1
Akhtar, M1
Raisuddin, S1
Bao, C1
Lv, J1
Chen, JR1
Wei, GZ1
Liu, N1
Wang, YT1
Ding, Z1
Liu, WB1
Li, XD1
Cao, HJ1
Sheng, J1
Liu, KY1
He, J1
Tao, FB1
Wang, QN1
Li, Y1
Yan, B1
Wu, Y1
Peng, Q1
Wei, Y1
Chen, Y1
Zhang, Y2
Ma, N1
Yang, X1
Ma, P1
Zhou, Y1
Ma, T1
Yan, M1
Meng, X1
Wu, J1
Ding, J1
Han, X1
Li, D1
Cui, Y1
Zhang, X1
Yin, K1
Qi, X1
Zhang, J1
Li, S2
Lin, H1
Xiong, Z1
Zeng, Y1
Zhou, J1
Shu, R1
Xie, X1
Fu, Z1
Wang, X1
Han, B1
Wu, P1
Lv, Y1
Lu, J1
Yang, Q1
Li, J1
Zhu, Y1
Zhang, Z1
Oluranti, OI1
Alabi, BA1
Michael, OS1
Ojo, AO1
Fatokun, BP1
Maestre-Batlle, D1
Pena, OM1
Huff, RD1
Randhawa, A1
Carlsten, C1
Bølling, AK1
Kassab, RB1
Lokman, MS1
Essawy, EA1
Peixoto, AR1
Santos, TM1
Brandt, JZ1
Delella, FK1
Gonçalves, BF1
Campos, SG1
Taboga, SR1
Favaro, WJ1
Domeniconi, RF1
Scarano, WR1

Other Studies

13 other studies available for dibutyl phthalate and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Enhancement of placental inflammation by Dibutyl Phthalate.
    Journal of reproductive immunology, 2021, Volume: 147

    Topics: Brain-Derived Neurotrophic Factor; Dibutyl Phthalate; Environmental Pollutants; Female; Gene Express

2021
mRNA expression and protein-protein interaction (PPI) network analysis of adrenal steroidogenesis in response to exposure to phthalates in rats.
    Environmental toxicology and pharmacology, 2022, Volume: 89

    Topics: Adrenal Glands; Animals; Cytokines; Dibutyl Phthalate; Diethylhexyl Phthalate; Glucocorticoids; Infl

2022
Chronic inflammation as a potential mediator between phthalate exposure and depressive symptoms.
    Ecotoxicology and environmental safety, 2022, Mar-15, Volume: 233

    Topics: Aged; Depression; Dibutyl Phthalate; Environmental Exposure; Environmental Pollutants; Humans; Infla

2022
Ferroptosis participates in dibutyl phthalate-aggravated allergic asthma in ovalbumin-sensitized mice.
    Ecotoxicology and environmental safety, 2023, Volume: 256

    Topics: Animals; Asthma; Dibutyl Phthalate; Ferroptosis; Hypersensitivity; Inflammation; Lung; Mice; Mice, I

2023
Exposure of DBP in gestation induces inflammation of testicular Sertoli cells in progeny by activating NLRP3 inflammasomes.
    The Science of the total environment, 2020, Mar-10, Volume: 707

    Topics: Animals; Dibutyl Phthalate; Inflammasomes; Inflammation; Interleukin-1beta; Male; NLR Family, Pyrin

2020
Dibutyl phthalate-induced oxidative stress, inflammation and apoptosis in grass carp hepatocytes and the therapeutic use of taxifolin.
    The Science of the total environment, 2021, Apr-10, Volume: 764

    Topics: Animals; Apoptosis; Carps; Dibutyl Phthalate; Hepatocytes; Inflammation; Oxidative Stress; Quercetin

2021
Exposure to dibutyl phthalate impairs lipid metabolism and causes inflammation via disturbing microbiota-related gut-liver axis.
    Acta biochimica et biophysica Sinica, 2020, Dec-29, Volume: 52, Issue:12

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Body Weight; Colon

2020
Dibutyl phthalate induces allergic airway inflammation in rats via inhibition of the Nrf2/TSLP/JAK1 pathway.
    Environmental pollution (Barking, Essex : 1987), 2020, Volume: 267

    Topics: Animals; Cytokines; Dibutyl Phthalate; Inflammation; Janus Kinase 1; Mice; NAD(P)H Dehydrogenase (Qu

2020
Rutin prevents cardiac oxidative stress and inflammation induced by bisphenol A and dibutyl phthalate exposure via NRF-2/NF-κB pathway.
    Life sciences, 2021, Nov-01, Volume: 284

    Topics: Animals; Benzhydryl Compounds; Creatine Kinase; Dibutyl Phthalate; Inflammation; Myocardium; NF-E2-R

2021
Dibutyl phthalate modulates phenotype of granulocytes in human blood in response to inflammatory stimuli.
    Toxicology letters, 2018, Oct-15, Volume: 296

    Topics: Adult; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD24 Antigen; Cytokines; Dibutyl Phtha

2018
Neurochemical alterations following the exposure to di-n-butyl phthalate in rats.
    Metabolic brain disease, 2019, Volume: 34, Issue:1

    Topics: Animals; Apoptosis; Brain; Catalase; Dibutyl Phthalate; Glutathione Peroxidase; Inflammation; Interl

2019
Gestational and lactational exposition to Di-N-butyl-phthalate (DBP) increases inflammation and preneoplastic lesions in prostate of wistar rats after carcinogenic N-methyl-N-nitrosourea (MNU) plus testosterone protocol.
    Environmental toxicology, 2016, Volume: 31, Issue:10

    Topics: Animals; Blotting, Western; Dibutyl Phthalate; Estrogen Receptor alpha; Female; Inflammation; Lactat

2016