dibutyl phthalate has been researched along with Disease Models, Animal in 21 studies
Dibutyl Phthalate: A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
dibutyl phthalate : A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Curcumin (Cur) has been used extensively in dietary supplement with antioxidant and anti-apoptotic properties." | 1.62 | Curcumin decreases dibutyl phthalate-induced renal dysfunction in Kunming mice via inhibiting oxidative stress and apoptosis. ( Chen, X; Huang, J; Jin, D; Liang, F; Xi, J; Zhu, X, 2021) |
| "Dibutyl phthalate (DBP) is a plasticizer used for many consumer products including cosmetics." | 1.46 | Dibutyl Phthalate Rather than Monobutyl Phthalate Facilitates Contact Hypersensitivity to Fluorescein Isothiocyanate in a Mouse Model. ( Imai, Y; Kurohane, K; Ogawa, E; Sekiguchi, K; Tsutsumi, M, 2017) |
| "A mouse xenograft model of prostate cancer was generated, and immunohistochemical and BrdU assay were carried out to determine the effect of DBP in this mouse model." | 1.40 | The estrogen receptor signaling pathway activated by phthalates is linked with transforming growth factor-β in the progression of LNCaP prostate cancer models. ( Choi, KC; Hwang, KA; Lee, HR, 2014) |
| "While the frequency of undescended testes after 200 mg/kg DBP exposure in the orl strain appeared increased, these data were not statistically significant." | 1.35 | The orl rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure. ( Barthold, JS; Campion, L; Herrmann, R; Johnson, KJ; McCahan, SM; Si, X, 2008) |
| " With exposed dose increasing, the serum testosterone (T) levels of male rats inversely decreased, and in the same dosage group the serum T levels of hypospadiac rats were significantly lower than the levels of nonhypospadiac counterparts." | 1.34 | Study on developmental abnormalities in hypospadiac male rats induced by maternal exposure to di-n-butyl phthalate (DBP). ( Jiang, J; Ma, L; Wang, X; Yuan, L; Zhang, W, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 10 (47.62) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Shiba, T | 1 |
| Maruyama, T | 1 |
| Kurohane, K | 2 |
| Iwasaki, Y | 1 |
| Watanabe, T | 1 |
| Imai, Y | 2 |
| Zhou, S | 1 |
| Han, M | 1 |
| Ren, Y | 1 |
| Yang, X | 3 |
| Duan, L | 1 |
| Zeng, Y | 1 |
| Li, J | 2 |
| Liang, F | 1 |
| Xi, J | 1 |
| Chen, X | 1 |
| Huang, J | 1 |
| Jin, D | 1 |
| Zhu, X | 1 |
| Zhou, X | 1 |
| Zhang, T | 1 |
| Song, L | 1 |
| Wang, Y | 1 |
| Zhang, Q | 1 |
| Cong, R | 1 |
| Ji, C | 1 |
| Luan, J | 1 |
| Yao, L | 1 |
| Zhang, W | 2 |
| Song, N | 1 |
| Wang, S | 1 |
| van den Driesche, S | 2 |
| Kilcoyne, KR | 1 |
| Wagner, I | 1 |
| Rebourcet, D | 1 |
| Boyle, A | 1 |
| Mitchell, R | 1 |
| McKinnell, C | 3 |
| Macpherson, S | 3 |
| Donat, R | 1 |
| Shukla, CJ | 1 |
| Jorgensen, A | 1 |
| Meyts, ER | 1 |
| Skakkebaek, NE | 1 |
| Sharpe, RM | 6 |
| Zhu, YP | 1 |
| Chen, L | 1 |
| Wang, XJ | 1 |
| Jiang, QH | 1 |
| Bei, XY | 1 |
| Sun, WL | 2 |
| Xia, SJ | 1 |
| Jiang, JT | 2 |
| Lara, NLM | 1 |
| França, LR | 1 |
| Sekiguchi, K | 1 |
| Ogawa, E | 1 |
| Tsutsumi, M | 1 |
| Wu, Y | 2 |
| Yan, B | 2 |
| Zhu, Y | 1 |
| Liu, X | 1 |
| Chen, M | 1 |
| Li, D | 1 |
| Lee, CC | 1 |
| Ma, P | 2 |
| Sun, Y | 1 |
| Zeng, J | 1 |
| Chen, Y | 1 |
| Li, C | 1 |
| Song, P | 1 |
| Zhang, L | 1 |
| de Souza, NP | 1 |
| Cardoso, AF | 1 |
| Gomide, L | 1 |
| Lima, T | 1 |
| Miot, HA | 1 |
| Martino-Andrade, AJ | 1 |
| Arnold, LL | 1 |
| Pennington, KL | 1 |
| Cohen, SM | 1 |
| de Camargo, J | 1 |
| Nascimento E Pontes, MG | 1 |
| Lee, HR | 1 |
| Hwang, KA | 1 |
| Choi, KC | 1 |
| Johnson, KJ | 1 |
| McCahan, SM | 1 |
| Si, X | 1 |
| Campion, L | 1 |
| Herrmann, R | 1 |
| Barthold, JS | 1 |
| Shigeno, T | 1 |
| Katakuse, M | 1 |
| Fujita, T | 1 |
| Mukoyama, Y | 1 |
| Watanabe, H | 1 |
| Larson, RP | 1 |
| Zimmerli, SC | 1 |
| Comeau, MR | 1 |
| Itano, A | 1 |
| Omori, M | 1 |
| Iseki, M | 1 |
| Hauser, C | 1 |
| Ziegler, SF | 1 |
| Liu, SB | 1 |
| Ma, Z | 1 |
| Sun, XW | 1 |
| Hong, Y | 1 |
| Ma, L | 2 |
| Qin, C | 1 |
| Stratton, HJ | 1 |
| Liu, Q | 1 |
| Fisher, JS | 2 |
| Marchetti, N | 1 |
| Mahood, IK | 3 |
| Walker, M | 3 |
| Hallmark, N | 2 |
| Scott, H | 1 |
| Rivas, A | 1 |
| Hartung, S | 1 |
| Ivell, R | 1 |
| Mason, JI | 1 |
| Jiang, J | 1 |
| Yuan, L | 1 |
| Wang, X | 1 |
| Hutchison, GR | 1 |
| Scott, HM | 2 |
| Ferrara, D | 1 |
| Brown, R | 1 |
21 other studies available for dibutyl phthalate and Disease Models, Animal
| Article | Year |
|---|---|
TRPA1 and TRPV1 activation is a novel adjuvant effect mechanism in contact hypersensitivity.
Topics: Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Dermatitis, Contact; Dibutyl Phthala | 2009 |
Dibutyl phthalate aggravated asthma-like symptoms through oxidative stress and increasing calcitonin gene-related peptide release.
Topics: Animals; Asthma; Calcitonin Gene-Related Peptide; Cytokines; Dibutyl Phthalate; Disease Models, Anim | 2020 |
Curcumin decreases dibutyl phthalate-induced renal dysfunction in Kunming mice via inhibiting oxidative stress and apoptosis.
Topics: Animals; Animals, Outbred Strains; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; | 2021 |
Prenatal exposure to di-n-butyl phthalate induces erectile dysfunction in male adult rats.
Topics: Animals; Dibutyl Phthalate; Disease Models, Animal; Environmental Pollutants; Erectile Dysfunction; | 2021 |
Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window.
Topics: Animals; Dibutyl Phthalate; Disease Models, Animal; Female; Gonadal Dysgenesis; Humans; Male; Matern | 2017 |
Maternal exposure to di-n-butyl phthalate (DBP) induces renal fibrosis in adult rat offspring.
Topics: Animals; Apoptosis; Ascorbic Acid; Cell Proliferation; Dibutyl Phthalate; Disease Models, Animal; En | 2017 |
Dibutyl phthalate induced testicular dysgenesis originates after seminiferous cord formation in rats.
Topics: Animals; Dibutyl Phthalate; Disease Models, Animal; Female; Fetus; Gonadal Dysgenesis; Humans; Leydi | 2017 |
Dibutyl Phthalate Rather than Monobutyl Phthalate Facilitates Contact Hypersensitivity to Fluorescein Isothiocyanate in a Mouse Model.
Topics: Animals; CHO Cells; Cricetulus; Dermatitis, Contact; Dibutyl Phthalate; Disease Models, Animal; Fema | 2017 |
Oral exposure to dibutyl phthalate exacerbates chronic lymphocytic thyroiditis through oxidative stress in female Wistar rats.
Topics: Administration, Oral; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Autoantibodies; Dibutyl Phtha | 2017 |
Combined use of vitamin E and nimodipine ameliorates dibutyl phthalate-induced memory deficit and apoptosis in mice by inhibiting the ERK 1/2 pathway.
Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Calcium Channel Blockers; Calcium Signaling; Dib | 2019 |
Experimental cryptorchidism enhances testicular susceptibility to dibutyl phthalate or acrylamide in Sprague-Dawley rats.
Topics: Acrylamide; Animals; Cryptorchidism; Dibutyl Phthalate; Disease Models, Animal; Female; Male; Matern | 2019 |
The estrogen receptor signaling pathway activated by phthalates is linked with transforming growth factor-β in the progression of LNCaP prostate cancer models.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Dibutyl Phthalate; Disease Models, | 2014 |
The orl rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure.
Topics: Animals; Body Weight; Cryptorchidism; Dibutyl Phthalate; Disease Models, Animal; Dose-Response Relat | 2008 |
Phthalate ester-induced thymic stromal lymphopoietin mediates allergic dermatitis in mice.
Topics: Allergens; Animals; Cell Movement; Cytokines; Dendritic Cells; Dermatitis, Allergic Contact; Dibutyl | 2009 |
Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses.
Topics: Allergens; Animals; Cell Differentiation; Cell Line; Cell Migration Inhibition; Cell Proliferation; | 2010 |
The role of androgen-induced growth factor (FGF8) on genital tubercle development in a hypospadiac male rat model of prenatal exposure to di-n-butyl phthalate.
Topics: Animals; Dibutyl Phthalate; Disease Models, Animal; Environmental Pollutants; Female; Fibroblast Gro | 2012 |
Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate.
Topics: Age Factors; Animals; Body Weight; Dibutyl Phthalate; Disease Models, Animal; Female; Humans; Hyperp | 2003 |
Cellular origins of testicular dysgenesis in rats exposed in utero to di(n-butyl) phthalate.
Topics: Androgen Antagonists; Animals; Dibutyl Phthalate; Disease Models, Animal; Female; Humans; Leydig Cel | 2006 |
Study on developmental abnormalities in hypospadiac male rats induced by maternal exposure to di-n-butyl phthalate (DBP).
Topics: Animals; Animals, Newborn; Birth Weight; Dibutyl Phthalate; Disease Models, Animal; Dose-Response Re | 2007 |
Sertoli cell development and function in an animal model of testicular dysgenesis syndrome.
Topics: Animals; Biomarkers; Cell Count; Cryptorchidism; Dibutyl Phthalate; Disease Models, Animal; Follicle | 2008 |
In utero exposure to di(n-butyl) phthalate and testicular dysgenesis: comparison of fetal and adult end points and their dose sensitivity.
Topics: Animals; Cell Aggregation; Dibutyl Phthalate; Disease Models, Animal; Dose-Response Relationship, Dr | 2007 |