dibutyl phthalate has been researched along with Carcinoma, Hepatocellular in 2 studies
Dibutyl Phthalate: A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
dibutyl phthalate : A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we investigated the roles of four PAEs, butyl benzyl phthalate (BBP), dibutyl phthalate (DBP), dimethyl phthalate (DMP), and diethyl phthalate (DEP), in hepatocellular carcinoma (HCC) cells." | 4.02 | Phthalates promote the invasion of hepatocellular carcinoma cells by enhancing the interaction between Pregnane X receptor and E26 transformation specific sequence 1. ( Chen, A; Cui, K; Du, Y; Fang, P; Gao, Z; Ma, W; Shi, X; Wang, X; Wen, P; Yu, P, 2021) |
| " In another experiment, pregnant dams were treated with DBP until gd 19, with the start of DBP treatment moved 1 d later into gestation for each treatment group, with the final group dosed only on gd 19." | 1.32 | Di(n-butyl) phthalate impairs cholesterol transport and steroidogenesis in the fetal rat testis through a rapid and reversible mechanism. ( Gaido, KW; Ross, SM; Thompson, CJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Du, Y | 1 |
| Shi, X | 1 |
| Ma, W | 1 |
| Wen, P | 1 |
| Yu, P | 1 |
| Wang, X | 1 |
| Fang, P | 1 |
| Chen, A | 1 |
| Gao, Z | 1 |
| Cui, K | 1 |
| Thompson, CJ | 1 |
| Ross, SM | 1 |
| Gaido, KW | 1 |
2 other studies available for dibutyl phthalate and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Phthalates promote the invasion of hepatocellular carcinoma cells by enhancing the interaction between Pregnane X receptor and E26 transformation specific sequence 1.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Dibutyl Phthalate; Endocrin | 2021 |
Di(n-butyl) phthalate impairs cholesterol transport and steroidogenesis in the fetal rat testis through a rapid and reversible mechanism.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholesterol; Dibutyl Phthalate; DNA-Binding Pr | 2004 |