dibutyl phthalate has been researched along with Cancer of Prostate in 7 studies
Dibutyl Phthalate: A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
dibutyl phthalate : A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prostate cancer is one of the most commonly diagnosed cancers in man." | 1.48 | Phthalates promote prostate cancer cell proliferation through activation of ERK5 and p38. ( Deng, F; Geng, S; Huang, C; Li, X; Liang, Z; Ma, X; Wu, J; Wu, R; Xie, C; Zhong, C; Zhu, M; Zhu, W, 2018) |
| "A mouse xenograft model of prostate cancer was generated, and immunohistochemical and BrdU assay were carried out to determine the effect of DBP in this mouse model." | 1.40 | The estrogen receptor signaling pathway activated by phthalates is linked with transforming growth factor-β in the progression of LNCaP prostate cancer models. ( Choi, KC; Hwang, KA; Lee, HR, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Bu, H | 1 |
| Tang, S | 1 |
| Liu, G | 1 |
| Miao, C | 1 |
| Zhou, X | 2 |
| Yang, H | 1 |
| Liu, B | 1 |
| Zhang, T | 1 |
| Wu, J | 2 |
| Zhang, X | 1 |
| Wang, S | 1 |
| Wang, Z | 1 |
| Kismali, G | 1 |
| Yurdakok-Dikmen, B | 1 |
| Kuzukiran, O | 1 |
| Arslan, P | 1 |
| Filazi, A | 1 |
| Zhu, M | 1 |
| Huang, C | 1 |
| Ma, X | 1 |
| Wu, R | 1 |
| Zhu, W | 1 |
| Li, X | 1 |
| Liang, Z | 1 |
| Deng, F | 1 |
| Geng, S | 1 |
| Xie, C | 1 |
| Zhong, C | 1 |
| Lee, HR | 1 |
| Hwang, KA | 1 |
| Choi, KC | 1 |
| Hrubá, E | 1 |
| Pernicová, Z | 1 |
| Pálková, L | 1 |
| Souček, K | 1 |
| Vondráček, J | 1 |
| Machala, M | 1 |
| de Jesus, MM | 1 |
| Negrin, AC | 1 |
| Taboga, SR | 1 |
| Pinto-Fochi, ME | 1 |
| Góes, RM | 1 |
7 other studies available for dibutyl phthalate and Cancer of Prostate
| Article | Year |
|---|---|
In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α pretreatment.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Dibutyl Phthalate; Forkhead Box Protein M1; Gene Expr | 2023 |
Pharmacophore based in silico study with laboratory verification-environmental explanation of prostate cancer recurrence.
Topics: Androgen Antagonists; Computer Simulation; Dibutyl Phthalate; Humans; Laboratories; Male; Phthalic A | 2021 |
Phthalate induced toxicity in prostate cancer cell lines and effects of alpha lipoic acid.
Topics: Adenocarcinoma; Cell Death; Cell Line, Tumor; Cell Proliferation; Dibutyl Phthalate; Diethylhexyl Ph | 2017 |
Phthalates promote prostate cancer cell proliferation through activation of ERK5 and p38.
Topics: Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Dibutyl Phth | 2018 |
The estrogen receptor signaling pathway activated by phthalates is linked with transforming growth factor-β in the progression of LNCaP prostate cancer models.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Dibutyl Phthalate; Disease Models, | 2014 |
Phthalates deregulate cell proliferation, but not neuroendocrine transdifferentiation, in human LNCaP prostate cancer cell model.
Topics: Cell Count; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transdifferentiation; Dibutyl Pht | 2014 |
Histopathological alterations in the prostates of Mongolian gerbils exposed to a high-fat diet and di-n-butyl phthalate individually or in combination.
Topics: Animals; Cytokines; Dibutyl Phthalate; Diet, High-Fat; Endocrine Disruptors; Gerbillinae; Hormones; | 2015 |