Page last updated: 2024-10-26

dibutyl phthalate and Asthma

dibutyl phthalate has been researched along with Asthma in 3 studies

Dibutyl Phthalate: A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
dibutyl phthalate : A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
" Although there is growing evidence supporting a link between DBP exposure and allergic airway inflammation, there is less information concerned with whether the ferroptosis pathway is involved in DBP-aggravated allergic asthma in ovalbumin (OVA)-sensitized mice."8.31Ferroptosis participates in dibutyl phthalate-aggravated allergic asthma in ovalbumin-sensitized mice. ( Chen, Y; Li, Y; Ma, N; Ma, P; Peng, Q; Wei, Y; Wu, Y; Yan, B; Yang, X; Zhang, Y, 2023)
" Although there is growing evidence supporting a link between DBP exposure and allergic airway inflammation, there is less information concerned with whether the ferroptosis pathway is involved in DBP-aggravated allergic asthma in ovalbumin (OVA)-sensitized mice."4.31Ferroptosis participates in dibutyl phthalate-aggravated allergic asthma in ovalbumin-sensitized mice. ( Chen, Y; Li, Y; Ma, N; Ma, P; Peng, Q; Wei, Y; Wu, Y; Yan, B; Yang, X; Zhang, Y, 2023)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's3 (100.00)2.80

Authors

AuthorsStudies
Leung, C1
Ryu, MH1
Bølling, AK1
Maestre-Batlle, D1
Rider, CF1
Hüls, A1
Urtatiz, O1
MacIsaac, JL1
Lau, KS1
Lin, DTS1
Kobor, MS1
Carlsten, C1
Li, Y1
Yan, B1
Wu, Y1
Peng, Q1
Wei, Y1
Chen, Y1
Zhang, Y1
Ma, N1
Yang, X2
Ma, P1
Zhou, S1
Han, M1
Ren, Y1
Duan, L1
Zeng, Y1
Li, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Phthalate Inhalation on Airway Immunology: A Controlled Human Exposure Study[NCT02688478]20 participants (Anticipated)Interventional2017-02-02Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for dibutyl phthalate and Asthma

ArticleYear
Peroxisome proliferator-activated receptor gamma gene variants modify human airway and systemic responses to indoor dibutyl phthalate exposure.
    Respiratory research, 2022, Sep-16, Volume: 23, Issue:1

    Topics: Allergens; Asthma; Cross-Over Studies; Dibutyl Phthalate; Humans; Immunoglobulin E; Plasticizers; PP

2022

Other Studies

2 other studies available for dibutyl phthalate and Asthma

ArticleYear
Ferroptosis participates in dibutyl phthalate-aggravated allergic asthma in ovalbumin-sensitized mice.
    Ecotoxicology and environmental safety, 2023, Volume: 256

    Topics: Animals; Asthma; Dibutyl Phthalate; Ferroptosis; Hypersensitivity; Inflammation; Lung; Mice; Mice, I

2023
Dibutyl phthalate aggravated asthma-like symptoms through oxidative stress and increasing calcitonin gene-related peptide release.
    Ecotoxicology and environmental safety, 2020, Volume: 199

    Topics: Animals; Asthma; Calcitonin Gene-Related Peptide; Cytokines; Dibutyl Phthalate; Disease Models, Anim

2020