dibutyl phthalate has been researched along with Abdominal Cryptorchidism in 17 studies
Dibutyl Phthalate: A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
dibutyl phthalate : A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to investigate the mechanism of dibutyl phthalate (DBP) induced hypospadias and shortened anogenital distance (AGD)." | 7.81 | The mechanism underlying dibutyl phthalate induced shortened anogenital distance and hypospadias in rats. ( Chen, X; Feng, J; Li, N; Yuan, J; Zhang, W; Zhou, X, 2015) |
| "The purpose of this study was to investigate the mechanism of dibutyl phthalate (DBP) induced hypospadias and shortened anogenital distance (AGD)." | 3.81 | The mechanism underlying dibutyl phthalate induced shortened anogenital distance and hypospadias in rats. ( Chen, X; Feng, J; Li, N; Yuan, J; Zhang, W; Zhou, X, 2015) |
| "Hypospadias and cryptorchidism are the most common congenital malformations in male neonates, both of which are also the important clinical manifestations of testicular dysgenesis syndrome and share a same origin." | 1.72 | Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males. ( Abulimiti, G; Cong, R; Ji, C; Luan, J; Song, N; Wang, Y; Yang, J; Yao, L; Zhang, Q; Zhang, X; Zhou, X, 2022) |
| "Dibutyl phthalate (DBP) was used at a high dose level (750 mg/kg bw/day) as an established positive control substance for anti-androgenic effects on the developing male reproductive tract." | 1.56 | Systematic comparison of the male reproductive tract in fetal and adult Wistar rats exposed to DBP and DINP in utero during the masculinisation programming window. ( Inglis, F; Langsch, A; Otter, R; Palermo, C; Shoker, S; van den Driesche, S, 2020) |
| "While the frequency of undescended testes after 200 mg/kg DBP exposure in the orl strain appeared increased, these data were not statistically significant." | 1.35 | The orl rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure. ( Barthold, JS; Campion, L; Herrmann, R; Johnson, KJ; McCahan, SM; Si, X, 2008) |
| "Cryptorchidism is a common reproductive abnormality, possibly resulting from abnormal hormone production/action by the fetal testis." | 1.33 | Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate. ( Haag, F; Hallmark, N; Hartung, S; Ivell, R; Jégou, B; Koch-Nolte, F; Mahood, K; McKinnell, C; Scott, H; Sharpe, RM; Staub, C, 2005) |
| "The objective of this study was to determine the susceptible days for the adverse effects of di-n-butyl phthalate (DBP) on development of reproductive system in male offspring following maternal administration on successive 3-day period during late pregnancy." | 1.31 | Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy. ( Ema, M; Kawashima, K; Miyawaki, E, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, X | 3 |
| Zhang, X | 1 |
| Abulimiti, G | 1 |
| Wang, Y | 1 |
| Zhang, Q | 1 |
| Cong, R | 1 |
| Ji, C | 1 |
| Luan, J | 1 |
| Yao, L | 1 |
| Yang, J | 1 |
| Song, N | 1 |
| Elwood, JM | 1 |
| van den Driesche, S | 1 |
| Shoker, S | 1 |
| Inglis, F | 1 |
| Palermo, C | 1 |
| Langsch, A | 1 |
| Otter, R | 1 |
| de Souza, NP | 1 |
| Cardoso, AF | 1 |
| Gomide, L | 1 |
| Lima, T | 1 |
| Miot, HA | 1 |
| Martino-Andrade, AJ | 1 |
| Arnold, LL | 1 |
| Pennington, KL | 1 |
| Cohen, SM | 1 |
| de Camargo, J | 1 |
| Nascimento E Pontes, MG | 1 |
| Li, N | 1 |
| Chen, X | 1 |
| Zhang, W | 2 |
| Yuan, J | 1 |
| Feng, J | 1 |
| Shen, H | 1 |
| Liao, K | 1 |
| Wu, HF | 1 |
| Lu, HC | 1 |
| Li, Y | 1 |
| Li, Z | 1 |
| Sharpe, RM | 3 |
| Johnson, KJ | 1 |
| McCahan, SM | 1 |
| Si, X | 1 |
| Campion, L | 1 |
| Herrmann, R | 1 |
| Barthold, JS | 1 |
| Kim, TS | 1 |
| Jung, KK | 1 |
| Kim, SS | 1 |
| Kang, IH | 1 |
| Baek, JH | 1 |
| Nam, HS | 1 |
| Hong, SK | 1 |
| Lee, BM | 1 |
| Hong, JT | 1 |
| Oh, KW | 1 |
| Kim, HS | 1 |
| Han, SY | 1 |
| Kang, TS | 1 |
| Carran, M | 1 |
| Shaw, IC | 1 |
| McBride, D | 1 |
| Schep, L | 1 |
| Elwood, M | 1 |
| Borman, B | 1 |
| Nakahara, H | 1 |
| Shono, T | 1 |
| Suita, S | 1 |
| McKinnell, C | 2 |
| Mahood, K | 1 |
| Hallmark, N | 1 |
| Scott, H | 1 |
| Ivell, R | 1 |
| Staub, C | 1 |
| Jégou, B | 1 |
| Haag, F | 1 |
| Koch-Nolte, F | 1 |
| Hartung, S | 1 |
| Hutchison, GR | 1 |
| Scott, HM | 1 |
| Walker, M | 1 |
| Ferrara, D | 1 |
| Mahood, IK | 1 |
| Mylchreest, E | 1 |
| Sar, M | 1 |
| Cattley, RC | 1 |
| Foster, PM | 1 |
| Ema, M | 1 |
| Miyawaki, E | 1 |
| Kawashima, K | 1 |
17 other studies available for dibutyl phthalate and Abdominal Cryptorchidism
| Article | Year |
|---|---|
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Topics: Animals; Cryptorchidism; Dibutyl Phthalate; Endocrine Disruptors; Female; Genitalia; Humans; Hypospa | 2022 |
Hypospadias, cryptorchidism, and breast cancer in children born to New Zealand servicemen who served in Malaya and may have had exposure to dibutyl phthalate: review of a previous study and updated review of international literature.
Topics: Breast Neoplasms; Child; Cryptorchidism; Dibutyl Phthalate; Female; Humans; Hypospadias; Malaysia; M | 2023 |
Systematic comparison of the male reproductive tract in fetal and adult Wistar rats exposed to DBP and DINP in utero during the masculinisation programming window.
Topics: Animals; Cryptorchidism; Dibutyl Phthalate; Dose-Response Relationship, Drug; Endocrine Disruptors; | 2020 |
Experimental cryptorchidism enhances testicular susceptibility to dibutyl phthalate or acrylamide in Sprague-Dawley rats.
Topics: Acrylamide; Animals; Cryptorchidism; Dibutyl Phthalate; Disease Models, Animal; Female; Male; Matern | 2019 |
The mechanism underlying dibutyl phthalate induced shortened anogenital distance and hypospadias in rats.
Topics: Anal Canal; Animals; Biomarkers; Cryptorchidism; Dibutyl Phthalate; Dose-Response Relationship, Drug | 2015 |
In utero exposure of high-dose di- n-butyl phthalate resulted in opposite effects on testicular cell apoptosis in late embryonic and pubertal male rat offspring.
Topics: Animals; Apoptosis; Cells, Cultured; Cryptorchidism; Dibutyl Phthalate; Disorders of Sex Development | 2017 |
"Additional" effects of phthalate mixtures on fetal testosterone production.
Topics: Animals; Cryptorchidism; Dibutyl Phthalate; Diethylhexyl Phthalate; Dose-Response Relationship, Drug | 2008 |
The orl rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure.
Topics: Animals; Body Weight; Cryptorchidism; Dibutyl Phthalate; Disease Models, Animal; Dose-Response Relat | 2008 |
Effects of in utero exposure to DI(n-Butyl) phthalate on development of male reproductive tracts in Sprague-Dawley rats.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Anal Canal; Animals; Body Weight; Cryptorchidism; Dibutyl Pht | 2010 |
New Zealand Malayan war veterans' exposure to dibutylphthalate is associated with an increased incidence of cryptorchidism, hypospadias and breast cancer in their children.
Topics: Acaricides; Adult; Breast Neoplasms; Clothing; Cryptorchidism; Dibutyl Phthalate; Female; Genital Di | 2012 |
Comment on Carran and Shaw's "New Zealand Malayan war veterans' exposure to dibutylphthalate" article.
Topics: Acaricides; Breast Neoplasms; Cryptorchidism; Dibutyl Phthalate; Female; Humans; Hypospadias; Male; | 2012 |
Increases in disease in Malayan war veterans' children may be misleading.
Topics: Acaricides; Breast Neoplasms; Cryptorchidism; Dibutyl Phthalate; Female; Humans; Hypospadias; Male; | 2012 |
[Effects of prenatal exposure to phthalate ester on both testicular descent and urogenital development in rats].
Topics: Animals; Cryptorchidism; Dibutyl Phthalate; Female; Hypospadias; Male; Pregnancy; Prenatal Exposure | 2003 |
Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate.
Topics: Animals; Cryptorchidism; Dibutyl Phthalate; DNA Primers; Female; Gene Expression Regulation, Develop | 2005 |
Sertoli cell development and function in an animal model of testicular dysgenesis syndrome.
Topics: Animals; Biomarkers; Cell Count; Cryptorchidism; Dibutyl Phthalate; Disease Models, Animal; Follicle | 2008 |
Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.
Topics: Abnormalities, Drug-Induced; Androgen Antagonists; Androgens; Animals; Animals, Newborn; Cryptorchid | 1999 |
Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy.
Topics: Animals; Body Weight; Cryptorchidism; Dibutyl Phthalate; Embryonic and Fetal Development; Female; Ma | 2000 |