dibucaine has been researched along with Schizophrenia in 1 studies
Dibucaine: A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
cinchocaine : A monocarboxylic acid amide that is the 2-(diethylamino)ethyl amide of 2-butoxyquinoline-4-carboxylic acid. One of the most potent and toxic of the long-acting local anesthetics, its parenteral use was restricted to spinal anesthesia. It is now generally only used (usually as the hydrochloride) in creams and ointments and in suppositories for temporary relief of pain and itching associated with skin and anorectal conditions.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moreover, past substance abuse may accentuate hippocampal volume reduction." | 1.36 | Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia. ( Aggernaes, B; Baaré, W; Ebdrup, BH; Glenthøj, B; Langkilde, AR; Lublin, H; Paulson, OB; Rasmussen, H; Skimminge, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ebdrup, BH | 1 |
| Glenthøj, B | 1 |
| Rasmussen, H | 1 |
| Aggernaes, B | 1 |
| Langkilde, AR | 1 |
| Paulson, OB | 1 |
| Lublin, H | 1 |
| Skimminge, A | 1 |
| Baaré, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 5-HT2A-receptor Binding: Implications for the Pathophysiology of Schizophrenia and Effects of Treatment With Antipsychotic Drugs[NCT00207064] | 46 participants (Actual) | Interventional | 2004-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for dibucaine and Schizophrenia
| Article | Year |
|---|---|
Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia.
Topics: Adolescent; Adult; Benzydamine; Brain; Caudate Nucleus; Cerebral Ventricles; Dibucaine; Drug Combina | 2010 |