Page last updated: 2024-10-26

dibucaine and Muscle Contraction

dibucaine has been researched along with Muscle Contraction in 16 studies

Dibucaine: A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
cinchocaine : A monocarboxylic acid amide that is the 2-(diethylamino)ethyl amide of 2-butoxyquinoline-4-carboxylic acid. One of the most potent and toxic of the long-acting local anesthetics, its parenteral use was restricted to spinal anesthesia. It is now generally only used (usually as the hydrochloride) in creams and ointments and in suppositories for temporary relief of pain and itching associated with skin and anorectal conditions.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" Circular muscle contractions due to nerveside are blocked by hexamethonium, nicotine, morphine, atropine and hyoscine."3.65The action of nerveside, a peptide extracted from brain, on myenteric ganglia in Auerbach's plexus. ( Soh, NM; Toh, CC, 1971)
"The mivacurium infusion rate was adjusted to maintain single twitch depression at 95 +/- 4% of control."2.68Prolonged mivacurium infusion in young and elderly adults. ( Chakravorti, S; Cook, DR; Denman, W; Goudsouzian, N; Schwartz, A; Yang, HS, 1997)
"Mivacurium 0."1.28Influence of plasma cholinesterase activity on recovery from mivacurium-induced neuromuscular blockade in phenotypically normal patients. ( Jensen, E; Jensen, FS; Ostergaard, D; Skovgaard, LT; Viby-Mogensen, J, 1992)
"Verapamil and D600 were approximately equivalent in their inhibitory effect but were significantly more potent (p < ."1.26Spasmolytic action of verapamil, D600 and cinchocaine on the rat vas deferens. ( Lin, CS; Swamy, VC, 1980)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199013 (81.25)18.7374
1990's3 (18.75)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BOWMAN, WC1
GOLDBERG, AA1
RAPER, C1
JUDAH, JD1
WILLOUGHBY, DA1
Lin, CS1
Swamy, VC2
Goudsouzian, N1
Chakravorti, S1
Denman, W1
Schwartz, A1
Yang, HS1
Cook, DR1
Ostergaard, D1
Jensen, FS1
Jensen, E1
Skovgaard, LT1
Viby-Mogensen, J1
Hishinuma, S2
Uchida, MK2
Bell, C1
Triggle, DJ1
Luciani, S1
Furlanut, M1
Vohra, MM1
Soh, NM1
Toh, CC1
Usubiaga, JE1
Standaert, F1
Wilcox, WD1
Fuchs, F1
Daniel, EE1
Wolowyk, M1
Rump, S1

Trials

1 trial available for dibucaine and Muscle Contraction

ArticleYear
Prolonged mivacurium infusion in young and elderly adults.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:9

    Topics: Adolescent; Adult; Aged; Aging; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inh

1997

Other Studies

15 other studies available for dibucaine and Muscle Contraction

ArticleYear
A comparison between the effects of a tetanus and the effects of sympathomimetic amines on fast- and slow-contracting mammalian muscles.
    British journal of pharmacology and chemotherapy, 1962, Volume: 19

    Topics: Animals; Cats; Dibucaine; Electric Stimulation; Epinephrine; Isoproterenol; Mammals; Muscle Contract

1962
INHIBITORS OF SODIUM DEPENDENT RELAXATION OF GUINEA-PIG ILEUM.
    Journal of cellular and comparative physiology, 1964, Volume: 64

    Topics: Calcium; Dibucaine; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Ileum; Muscle Contractio

1964
Spasmolytic action of verapamil, D600 and cinchocaine on the rat vas deferens.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 244, Issue:1

    Topics: Animals; Calcium; Dibucaine; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smoo

1980
Influence of plasma cholinesterase activity on recovery from mivacurium-induced neuromuscular blockade in phenotypically normal patients.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterases; Dibucaine; Electric Stimulation; Flushing; Humans; Infu

1992
Blockade by the local anaesthetic, tetracaine, of desensitization of Ca-induced Ca release after muscarinic stimulation in smooth muscle.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: Animals; Caffeine; Calcium; Carbachol; Dibucaine; Female; Guinea Pigs; Histamine; In Vitro Technique

1991
Effects of local anaesthetics on short-term desensitization of guinea-pig taenia caecum to histamine.
    British journal of pharmacology, 1987, Volume: 92, Issue:4

    Topics: Anesthetics, Local; Animals; Calcium; Cecum; Dibucaine; Female; Guinea Pigs; Histamine; Histamine An

1987
Transmission from vasoconstrictor and vasodilator nerves to single smooth muscle cells of the guinea-pig uterine artery.
    The Journal of physiology, 1969, Volume: 205, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Arteries; Bretylium Compounds; Constriction; Dibucaine; D

1969
2-Halogenoethylamines and the role of Ca 2+ in adrenergic -receptor activation in the rat vas deferens.
    European journal of pharmacology, 1972, Volume: 19, Issue:1

    Topics: Animals; Binding Sites; Bromine; Calcium; Diazoxide; Dibucaine; Drug Antagonism; Drug Interactions;

1972
Interaction between dibucaine and K+ on smooth muscle.
    Pharmacological research communications, 1974, Volume: 6, Issue:2

    Topics: Acetylcholine; Action Potentials; Animals; Calcium; Colon; Dibucaine; Dose-Response Relationship, Dr

1974
An analysis of the contractile responses of the rat vas deferens to xylocaine (lidocaine) and procaine.
    European journal of pharmacology, 1970, Volume: 9, Issue:1

    Topics: Animals; Dibucaine; Dinitrophenols; Glucose; Glycolysis; Hydrogen-Ion Concentration; In Vitro Techni

1970
The action of nerveside, a peptide extracted from brain, on myenteric ganglia in Auerbach's plexus.
    The Journal of physiology, 1971, Volume: 213, Issue:3

    Topics: Animals; Atropine; Dibucaine; Ganglia; Gastrointestinal Motility; Hexamethonium Compounds; Histamine

1971
The effects of local anesthetics on motor nerve terminals.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 159, Issue:2

    Topics: Anesthetics, Local; Animals; Cats; Depression, Chemical; Dibucaine; Leg; Lidocaine; Muscle Contracti

1968
The effect of some local anesthetic compounds on sarcotubular calcium transport.
    Biochimica et biophysica acta, 1969, Volume: 180, Issue:1

    Topics: Animals; Biological Transport; Calcium; Dibucaine; Lidocaine; Muscle Contraction; Muscles; Procaine;

1969
The contractile response of the uterus to cocaine.
    Canadian journal of physiology and pharmacology, 1966, Volume: 44, Issue:5

    Topics: Acetylcholine; Animals; Atropine; Calcium; Catecholamines; Cocaine; Dibucaine; Diethylstilbestrol; E

1966
Some effects of cinchocaine on sarin-induced abnormalities of neuromuscular transmission in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 164, Issue:1

    Topics: Animals; Dibucaine; Drug Synergism; Electric Stimulation; Fluorides; Hexobarbital; Injections, Intra

1966