dibucaine has been researched along with Hemolysis in 14 studies
Dibucaine: A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
cinchocaine : A monocarboxylic acid amide that is the 2-(diethylamino)ethyl amide of 2-butoxyquinoline-4-carboxylic acid. One of the most potent and toxic of the long-acting local anesthetics, its parenteral use was restricted to spinal anesthesia. It is now generally only used (usually as the hydrochloride) in creams and ointments and in suppositories for temporary relief of pain and itching associated with skin and anorectal conditions.
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings indicated that the mechanism of dibucaine-induced hemolysis within a few seconds is through membrane lysis, whereas dibucaine-induced hemolysis at 30 min is caused by another mechanism." | 3.72 | [Ionic strength influences hemolytic action of dibucaine hydrochloride]. ( Hidaka, N; Katsuki, H; Takasaki, M; Tateyama, S, 2003) |
| "Trifluoperazine (TFP) is a potent antipsychotic agent, dibucaine (DBC) is a local anaesthetic and praziquantel (PZQ) is a highly effective agent against schistosomiasis." | 1.31 | Membrane effects of trifluoperazine, dibucaine and praziquantel on human erythrocytes. ( Brites, D; Brito, MA; Malheiros, SV; Meirelles, NC, 2000) |
| "2 micromol/L UCB for 10 min prior to the incubation with toxic concentrations of TFP (0." | 1.31 | Effect of bilirubin on toxicity induced by trifluoperazine, dibucaine and praziquantel to erythrocytes. ( Brites, D; Brito, MA; Malheiros, SV; Meirelles, NC, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katsuki, H | 3 |
| Komatsu, M | 1 |
| Egawa, H | 1 |
| Nagata, N | 1 |
| Takasaki, M | 3 |
| ANDERSEN, NB | 2 |
| GRAVENSTEIN, JS | 1 |
| Tateyama, S | 2 |
| Hidaka, N | 2 |
| Yano, T | 1 |
| Ibusuki, S | 1 |
| Rao, MN | 1 |
| Bhise, SB | 1 |
| Srivastava, RC | 1 |
| Malheiros, SV | 3 |
| Meirelles, NC | 3 |
| de Paula, E | 1 |
| Brito, MA | 2 |
| Brites, D | 2 |
| Gemba, M | 1 |
| Ushijima, H | 1 |
| Nakajima, M | 1 |
| Nakano, S | 1 |
| Waller, HD | 1 |
| Apostolov, K | 1 |
| Poste, G | 1 |
| Murofushi, M | 1 |
| Sato, T | 1 |
| Fujii, T | 1 |
| Daniel, EE | 1 |
| Wolowyk, M | 1 |
1 review available for dibucaine and Hemolysis
| Article | Year |
|---|---|
[Adverse effects of drugs in hereditary variants in the enzyme apparatus of the body].
Topics: Adenosine Triphosphatases; Adult; Aged; Cholinesterase Inhibitors; Coumarins; Dibucaine; Drug-Relate | 1968 |
13 other studies available for dibucaine and Hemolysis
| Article | Year |
|---|---|
[A comparative study of membrane destructive action of dibucaine HCl and bupivacaine HCl].
Topics: Anesthetics, Local; Bupivacaine; Dibucaine; Dose-Response Relationship, Drug; Erythrocyte Membrane; | 2002 |
EFFECTS OF LOCAL ANESTHETICS ON SODIUM AND POTASSIUM IN HUMAN RED CELLS.
Topics: Anesthetics, Local; Cocaine; Computers, Analog; Dibucaine; Electronic Data Processing; Erythrocytes; | 1965 |
[Ionic strength influences hemolytic action of dibucaine hydrochloride].
Topics: Anesthetics, Local; Dibucaine; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes; | 2003 |
[Glucose attenuating local anesthetic-induced hemolysis].
Topics: Anesthetics, Local; Dibucaine; Dose-Response Relationship, Drug; Erythrocyte Membrane; Glucose; Hemo | 2004 |
Antihemolytic action of surface active drugs.
Topics: Animals; Chlorpromazine; Dextropropoxyphene; Dibucaine; Goats; Hemolysis; Hypotonic Solutions; Phosp | 1984 |
Pathways involved in trifluoperazine-, dibucaine- and praziquantel-induced hemolysis.
Topics: Anesthetics, Local; Animals; Anthelmintics; Antipsychotic Agents; Dibucaine; Erythrocyte Membrane; E | 2000 |
Membrane effects of trifluoperazine, dibucaine and praziquantel on human erythrocytes.
Topics: Adult; Cholesterol; Dibucaine; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; In Vitro Techn | 2000 |
Effect of bilirubin on toxicity induced by trifluoperazine, dibucaine and praziquantel to erythrocytes.
Topics: Adult; Bilirubin; Cholesterol; Dibucaine; Drug Interactions; Erythrocytes; Hemoglobins; Hemolysis; H | 2001 |
Stimulation by trifluoperazine of p-aminohippurate accumulation in rat kidney cortical slices.
Topics: Adenosine Triphosphate; Aminohippuric Acids; Animals; Chlorpromazine; Dibucaine; Hemolysis; In Vitro | 1987 |
Interaction of Sendai virus with human erythrocytes: a system for the study of membrane fusion.
Topics: Adsorption; Blood Group Antigens; Calcium Chloride; Cell Fusion; Cell Membrane; Chlorides; Culture M | 1972 |
Protective effect of calcium ions on hypotonic hemolysis of human erythrocytes.
Topics: Calcium; Dibucaine; Erythrocytes; Hemolysis; Humans; Hypotonic Solutions; Ions; Magnesium; Phenylace | 1973 |
The effect of local anesthetic and pH on sodium and potassium flux in human red cells.
Topics: Biological Transport, Active; Cell Membrane Permeability; Cocaine; Depression, Chemical; Dibucaine; | 1968 |
The contractile response of the uterus to cocaine.
Topics: Acetylcholine; Animals; Atropine; Calcium; Catecholamines; Cocaine; Dibucaine; Diethylstilbestrol; E | 1966 |