dibucaine has been researched along with Apnea in 36 studies
Dibucaine: A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
cinchocaine : A monocarboxylic acid amide that is the 2-(diethylamino)ethyl amide of 2-butoxyquinoline-4-carboxylic acid. One of the most potent and toxic of the long-acting local anesthetics, its parenteral use was restricted to spinal anesthesia. It is now generally only used (usually as the hydrochloride) in creams and ointments and in suppositories for temporary relief of pain and itching associated with skin and anorectal conditions.
Apnea: A transient absence of spontaneous respiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "8) Abnormal variants of serum cholinesterase lead to prolonged apnea." | 7.67 | [Phenotype of plasma cholinesterase in prolonged apnea and sensitivity to succinylcholine]. ( Alcalay, A; Burnat, P; Jacquot, C; Zaoui, P, 1987) |
| " Homozygotes for the A gene product are at risk for prolonged apnea following exposure to the surgical anesthetics succinylcholine or mivacurium." | 3.74 | Molecular basis of succinylcholine sensitivity in a prairie Hutterite kindred and genetic characterization of the region containing the BCHE gene. ( Coghlan, G; Mauthe, J; Triggs-Raine, B; Zelinski, T, 2007) |
| " On the other hand, the two methods using butyrylthiocholine as substrate and that employing benzoylcholine showed limited clinical utility in discriminating subjects at risk of prolonged apnea (area under the ROC curve < or = 0." | 3.72 | Assay using succinyldithiocholine as substrate: the method of choice for the measurement of cholinesterase catalytic activity in serum to diagnose succinyldicholine sensitivity. ( Bonora, R; Ceriotti, F; Franzini, C; Lando, G; Mosca, A; Panteghini, M; Patrosso, MC; Zaninotto, M, 2003) |
| "8) Abnormal variants of serum cholinesterase lead to prolonged apnea." | 3.67 | [Phenotype of plasma cholinesterase in prolonged apnea and sensitivity to succinylcholine]. ( Alcalay, A; Burnat, P; Jacquot, C; Zaoui, P, 1987) |
| "The fluoride numbers (FN) of 144 individuals referred to our laboratory for dibucaine number (DN) determinations because of prolonged apnea following succinylcholine in the probands or relatives were determined by our new method using 2." | 3.66 | Floride inhibition in patients with atypical dibucaine-resistant plasmacholinesterase. ( Flynn, KB; Kothary, SP; Zsigmond, EK, 1979) |
| " Because of these reports, 23 patients with prolonged apnea after administration of succinylcholine were studied with Kalow's method for abnormal dibucaine number (DN), which characterizes this condition, and for the history of local anesthetic toxicity." | 3.65 | Survey of local anesthetic toxicity in the families of patients with atypical plasma cholinesterase. ( Eilderton, TE; Zsigmond, EK, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (88.89) | 18.7374 |
| 1990's | 2 (5.56) | 18.2507 |
| 2000's | 2 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mosca, A | 1 |
| Bonora, R | 1 |
| Ceriotti, F | 1 |
| Franzini, C | 1 |
| Lando, G | 1 |
| Patrosso, MC | 1 |
| Zaninotto, M | 1 |
| Panteghini, M | 1 |
| NIXON, JC | 1 |
| THIEL, CJ | 1 |
| Zelinski, T | 1 |
| Coghlan, G | 1 |
| Mauthe, J | 1 |
| Triggs-Raine, B | 1 |
| Brown, SS | 2 |
| Kalow, W | 1 |
| Pilz, W | 1 |
| Whittaker, M | 4 |
| Woronick, CL | 1 |
| Pasquariello, CA | 1 |
| Schwartz, RE | 1 |
| Simeon-Rudolf, V | 1 |
| Kovarik, Z | 1 |
| Skrinjarić-Spoljar, M | 1 |
| Evans, RT | 2 |
| Agarwal, DP | 1 |
| Schwenkenbecher, S | 1 |
| Srivastava, LM | 1 |
| Goedde, HW | 1 |
| Gerosky, T | 1 |
| O'Leary, J | 1 |
| Hunt, R | 1 |
| Hutchinson, MA | 1 |
| Kothary, SP | 1 |
| Flynn, KB | 1 |
| Zsigmond, EK | 3 |
| Geshelin, SA | 1 |
| Viby-Mogensen, J | 1 |
| Hanel, HK | 1 |
| Eilderton, TE | 1 |
| Baraka, A | 1 |
| Haroun, S | 1 |
| Bassili, M | 1 |
| Abu-Haider, G | 1 |
| Pronk, IR | 1 |
| van der Wal, SJ | 1 |
| Thé, TH | 1 |
| Burnat, P | 1 |
| Jacquot, C | 1 |
| Alcalay, A | 1 |
| Zaoui, P | 1 |
| Ukoha, AI | 1 |
| Nwoke, UN | 1 |
| Rahman, MM | 1 |
| Alam, MS | 1 |
| Nelson, TC | 1 |
| Burritt, MF | 1 |
| Bauld, HW | 1 |
| Gibson, PF | 1 |
| Jebson, PJ | 1 |
| Richardson, RB | 1 |
| Smith, JC | 1 |
| Derrick, WS | 1 |
| Liddell, J | 1 |
| Mone, JG | 1 |
| Mathie, WE | 1 |
| Peck, AW | 1 |
| Fishtal, A | 1 |
| Chapman, CN | 1 |
| McLellan, GH | 1 |
| Billings, JD | 1 |
| Litwiller, RW | 1 |
| King, J | 1 |
| Morgan, HG | 1 |
| Vickers, MD | 1 |
| Vetten, KB | 1 |
| Downs, JR | 1 |
| Zoerb, DL | 1 |
| Dietz, AA | 1 |
| Lubrano, T | 1 |
| Rubinstein, HM | 1 |
| Szeinberg, A | 1 |
| Pipano, S | 1 |
| Ostfeld, E | 1 |
| Hunter, AR | 2 |
| Thompson, JC | 1 |
2 reviews available for dibucaine and Apnea
| Article | Year |
|---|---|
The plasma cholinesteerases: a new perspective.
Topics: Acetylcholinesterase; Anesthesia, General; Apnea; Cholinesterases; Dibucaine; Fluorides; Genes; Gene | 1981 |
Pharmacogenetics. Cholinesterase variants and suxamethonium apnoea.
Topics: Alleles; Apnea; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Drug Hypersensitivity; Electr | 1968 |
34 other studies available for dibucaine and Apnea
| Article | Year |
|---|---|
Assay using succinyldithiocholine as substrate: the method of choice for the measurement of cholinesterase catalytic activity in serum to diagnose succinyldicholine sensitivity.
Topics: Anesthetics, Local; Apnea; Butyrylthiocholine; Cariostatic Agents; Catalysis; Cholinesterase Inhibit | 2003 |
APNEA DUE TO INHERITANCE OF ATYPICAL PSEUDOCHOLINESTERASE.
Topics: Abscess; Anesthesia; Anesthesia, General; Anesthesiology; Apnea; Butyrylcholinesterase; Cholinestera | 1964 |
Molecular basis of succinylcholine sensitivity in a prairie Hutterite kindred and genetic characterization of the region containing the BCHE gene.
Topics: Apnea; Butyrylcholinesterase; Canada; Dibucaine; Ethnicity; Female; Genetics, Population; Humans; Ma | 2007 |
Plasma cholinesterase deficiency in a neonate: a follow-up.
Topics: Apnea; Child, Preschool; Cholinesterases; Dibucaine; Female; Follow-Up Studies; Humans; Infant, Newb | 1995 |
An explanation for the different inhibitory characteristics of human serum butyrylcholinesterase phenotypes deriving from inhibition of atypical heterozygotes.
Topics: Apnea; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Dibucaine; Genetic Carrier Scre | 1999 |
[A spectrophotometric method for the determination of serum cholinesterase variants with succinyl choline as substrate (author's transl)].
Topics: Anesthesia; Animals; Apnea; Choline; Cholinesterase Inhibitors; Cholinesterases; Cytochrome c Group; | 1975 |
Prolonged apnea of an oral surgery patient after administration of succinylcholine.
Topics: Adolescent; Anesthesia, Dental; Anesthesia, General; Apnea; Butyrylcholinesterase; Cholinesterase In | 1979 |
Floride inhibition in patients with atypical dibucaine-resistant plasmacholinesterase.
Topics: Apnea; Choline O-Acetyltransferase; Dibucaine; Drug Resistance; Fluorides; Genotype; Heterozygote; H | 1979 |
[Peripheral paralysis or "bulbar threat"? (Further comment on the pathogenesis of respiratory arrest and vascular collapse during cerebrospinal anesthesia)].
Topics: Anesthesia, Spinal; Animals; Apnea; Blood Pressure; Bulbar Palsy, Progressive; Dibucaine; Dogs; Hear | 1978 |
A Danish cholinesterase research unit.
Topics: Apnea; Cholinesterases; Denmark; Dibucaine; Female; Genetic Variation; Genotype; Humans; Male; Pedig | 1977 |
Survey of local anesthetic toxicity in the families of patients with atypical plasma cholinesterase.
Topics: Anesthetics, Local; Apnea; Benzoylcholine; Cholinesterases; Dibucaine; Heterozygote; Homozygote; Hum | 1975 |
Response of the newborn to succinlycholine injection in homozygotic atypical mothers.
Topics: Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Apnea; Cesarean Section; Cholinesterases; D | 1975 |
[Familial examinations for the presence of atypical cholinesterase].
Topics: Adolescent; Anesthesia, General; Apnea; Appendectomy; Child, Preschool; Cholinesterase Inhibitors; C | 1975 |
[Phenotype of plasma cholinesterase in prolonged apnea and sensitivity to succinylcholine].
Topics: Anesthesia, General; Apnea; Cholinesterase Inhibitors; Dibucaine; Family; Female; Humans; Phenotype; | 1987 |
The prevalence of atypical serum cholinesterase in a Nigerian population.
Topics: Alleles; Anemia, Sickle Cell; Apnea; Butyrylcholinesterase; Cholinesterases; Dibucaine; Fluorides; G | 1987 |
Pesticide poisoning, succinylcholine-induced apnea, and pseudocholinesterase.
Topics: Apnea; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Humans; Pestici | 1986 |
Aetiology of prolonged apnoea after suxamethonium.
Topics: Adolescent; Adult; Aged; Apnea; Catalysis; Child; Child, Preschool; Cholinesterases; Dibucaine; Drug | 1974 |
Atypical plasma cholinesterase, succinylcholine, and prolonged apnea.
Topics: Aged; Anesthesia; Apnea; Cholinesterases; Dibucaine; Female; Humans; Succinylcholine; Time Factors | 1974 |
Qualitative defects of pseudocholinesterase activity.
Topics: Adolescent; Adult; Aged; Apnea; Child; Cholinesterases; Clinical Enzyme Tests; Cyclophosphamide; Dib | 1967 |
Aspects of suxamethonium hydrolysis in man and animals.
Topics: Acetylcholine; Acetylcholinesterase; Alleles; Animals; Apnea; Cats; Cholinesterase Inhibitors; Choli | 1970 |
An original approach to the diagnosis of scoline-induced apnoea.
Topics: Apnea; Cholinesterases; Dibucaine; Heterozygote; Homozygote; Humans; Hydrogen-Ion Concentration; Hyd | 1972 |
Suxamethonium sensitivity.
Topics: Anesthesia, General; Apnea; Blood Transfusion; Child; Cholinesterases; Dibucaine; Drug Hypersensitiv | 1967 |
A family study of atypical plasma cholinesterase activity.
Topics: Adult; Apnea; Child; Cholinesterases; Clinical Enzyme Tests; Diagnosis, Differential; Dibucaine; Fem | 1970 |
The temperature activity relationships of serum cholinesterases.
Topics: Apnea; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Fluorides; Humans; Phenotype; Succinyl | 1970 |
Initial experiences with the Cholinesterase Research Unit.
Topics: Apnea; Child; Cholinesterases; Dibucaine; Female; Fluorides; Genotype; Heterozygote; Humans; Male; M | 1970 |
Genetics--the anaesthetist at risk.
Topics: Apnea; Barbiturates; Dibucaine; Female; Fever; Humans; Hydrocarbons, Halogenated; Male; Nitrous Oxid | 1970 |
Plasma cholinesterase activity in newborns and infants.
Topics: Apnea; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Female; Halothane; Heart Block; Humans | 1971 |
Atypical pseudocholinesterase activity: a review and presentation of two cases.
Topics: Aged; Apnea; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Female; Genetics, Medical; Human | 1968 |
An additional pseudocholinesterase phenotype occurring in suxamethonium apnoea.
Topics: Apnea; Chlorides; Cholinesterases; Clinical Enzyme Tests; Dibucaine; Fluorides; Humans; Middle Aged; | 1968 |
Four families segregating for the silent gene for serum cholinesterase.
Topics: Adult; Apnea; Appendectomy; Child; Cholinesterases; Dibucaine; Enzymes; Female; Genes; Humans; Pulmo | 1965 |
A silent pseudocholinesterase gene. Marked suxamethonium sensitivity in a person heterozygous for the atypical and silent pseudocholinesterase genes.
Topics: Apnea; Blood Chemical Analysis; Cholinesterases; Dibucaine; Enzymes; Fluorides; Genes; Humans; Middl | 1965 |
Prolongation of the action of suxamethonium. A clinical investigation.
Topics: Acridines; Anesthesia, Endotracheal; Apnea; Blood Chemical Analysis; Cholinesterases; Dibucaine; Enz | 1966 |
Suxamethonium apnoea. A study of eighteen cases.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Apnea; Child; Child, Preschool; Cholinesterases; Dibuc | 1966 |
A study of the pseudocholinesterase in 78 cases of apnoea following suxamethonium.
Topics: Apnea; Chlorides; Cholinesterases; Dibucaine; Drug Hypersensitivity; Fluorides; Genes; Humans; Succi | 1966 |