Compounds > dibenzo(a,l)pyrene
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dibenzo(a,l)pyrene and Breast Cancer

dibenzo(a,l)pyrene has been researched along with Breast Cancer in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baird, WM; Keshava, C; Mahadevan, B; Musafia-Jeknic, T; Pecaj, A; Weston, A1
Baird, WM; Mahadevan, B; Musafia-Jeknic, T; Pereira, C1
Baird, WM; Hooven, LA1
Baird, WM; Lau, HH; Luch, A; Platt, KL; Ralston, SL; Seidel, A1
Baird, WM; Luch, A; Platt, KL; Ralston, SL; Seidel, A1
Baird, WM; Coffing, SL; Luch, A; Platt, KL; Ralston, SL; Seidel, A1
Baird, WM; Doehmer, J; Greim, H; Kudla, K; Luch, A; Seidel, A1
Freeman, JW; Gupta, RC; Smith, WA1

Other Studies

8 other study(ies) available for dibenzo(a,l)pyrene and Breast Cancer

ArticleYear
Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture standard reference material 1649a.
    Cancer research, 2005, Feb-15, Volume: 65, Issue:4

    Topics: Apoptosis; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Breast Neoplasms; Carcinogens; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cytochrome P-450 Enzyme System; DNA Adducts; DNA Damage; DNA Repair; Dust; Gene Expression; Humans; Isoenzymes

2005
Long-term effects of a standardized complex mixture of urban dust particulate on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 88, Issue:2

    Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Complex Mixtures; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA; DNA Adducts; Drug Combinations; Dust; Humans; Microsomes; Urban Health

2005
Proteomic analysis of MCF-7 cells treated with benzo[a]pyrene, dibenzo[a,l]pyrene, coal tar extract, and diesel exhaust extract.
    Toxicology, 2008, Jul-10, Volume: 249, Issue:1

    Topics: Benzo(a)pyrene; Benzopyrenes; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Coal Tar; Electrophoresis, Polyacrylamide Gel; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Proteome; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Vehicle Emissions

2008
The potent carcinogen dibenzo[a,l]pyrene is metabolically activated to fjord-region 11,12-diol 13,14-epoxides in human mammary carcinoma MCF-7 cell cultures.
    Cancer research, 1994, Feb-15, Volume: 54, Issue:4

    Topics: Benzopyrenes; Biotransformation; Breast Neoplasms; Carcinogens; DNA; Epoxy Compounds; Female; Humans; Tumor Cells, Cultured

1994
Stereoselective activation of dibenzo[a,l]pyrene to (-)-anti (11R,12S,13S,14R)- and (+)-syn(11S,12R,13S,14R)-11,12-diol-13,14-epoxides which bind extensively to deoxyadenosine residues of DNA in the human mammary carcinoma cell line MCF-7.
    Carcinogenesis, 1995, Volume: 16, Issue:12

    Topics: Benzopyrenes; Biotransformation; Breast Neoplasms; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Deoxyadenosines; Dihydroxydihydrobenzopyrenes; DNA Adducts; DNA, Neoplasm; Humans; Stereoisomerism; Tumor Cells, Cultured

1995
Stereoselective activation of dibenzo[a,l]pyrene and its trans-11,12-dihydrodiol to fjord region 11,12-diol 13,14-epoxides in a human mammary carcinoma MCF-7 cell-mediated V79 cell mutation assay.
    Chemical research in toxicology, 1997, Volume: 10, Issue:6

    Topics: Animals; Benzopyrenes; Breast Neoplasms; Carcinogens; Carcinoma; Cells, Cultured; Cricetinae; Cricetulus; Dihydroxydihydrobenzopyrenes; DNA Adducts; Epoxy Compounds; Humans; Mutagenicity Tests

1997
The level of DNA modification by (+)-syn-(11S,12R,13S,14R)- and (-)-anti-(11R,12S,13S,14R)-dihydrodiol epoxides of dibenzo[a,l]pyrene determined the effect on the proteins p53 and p21WAF1 in the human mammary carcinoma cell line MCF-7.
    Carcinogenesis, 1999, Volume: 20, Issue:5

    Topics: Benzopyrenes; Blotting, Western; Breast Neoplasms; Carcinogens; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dihydroxydihydrobenzopyrenes; DNA Adducts; DNA, Neoplasm; Epoxy Compounds; Female; Humans; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1999
Effect of chemopreventive agents on DNA adduction induced by the potent mammary carcinogen dibenzo[a,l]pyrene in the human breast cells MCF-7.
    Mutation research, 2001, Sep-01, Volume: 480-481

    Topics: Anticarcinogenic Agents; Antimutagenic Agents; Antineoplastic Agents; Benzopyrenes; Breast; Breast Neoplasms; Carcinogens; Cell Line; Chemoprevention; Chlorophyllides; DNA Adducts; Dose-Response Relationship, Drug; Female; Humans; Pyrazines; Thiones; Thiophenes

2001