diazoxide has been researched along with Weight Gain in 3 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Weight Gain: Increase in BODY WEIGHT over existing weight.
Excerpt | Relevance | Reference |
---|---|---|
"Diazoxide-treated obese and lean animals showed significantly lower postabsorptive plasma insulin concentrations (P < 0." | 5.29 | Modification of insulin resistance by diazoxide in obese Zucker rats. ( Alemzadeh, R; Maturo, J; Slonim, AE; Zdanowicz, MM, 1993) |
"Persistent suppression of hyperinsulinemia in genetically obese (fa/fa) Zucker rats by diazoxide (DZ) reduces food intake and weight gain; improves insulin sensitivity, glycemic control, and lipid profile; and enhances beta(3)-adrenergic function and lipolysis in adipose tissue." | 3.74 | Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker rats. ( Alemzadeh, R; Buchholz, M; Karlstad, MD; Tushaus, K, 2008) |
"Diazoxide-treated obese and lean animals showed significantly lower postabsorptive plasma insulin concentrations (P < 0." | 1.29 | Modification of insulin resistance by diazoxide in obese Zucker rats. ( Alemzadeh, R; Maturo, J; Slonim, AE; Zdanowicz, MM, 1993) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Alemzadeh, R | 2 |
Karlstad, MD | 1 |
Tushaus, K | 1 |
Buchholz, M | 1 |
Swaminathan, K | 1 |
Young, R | 1 |
Reid, W | 1 |
Slonim, AE | 1 |
Zdanowicz, MM | 1 |
Maturo, J | 1 |
3 other studies available for diazoxide and Weight Gain
Article | Year |
---|---|
Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker rats.
Topics: Adenylyl Cyclases; Animals; Basal Metabolism; Blood Glucose; Body Composition; Calorimetry, Indirect | 2008 |
The diagnosis was in her birthday party!
Topics: Aged, 80 and over; Blood Glucose; C-Peptide; Confusion; Diazoxide; Epilepsy, Tonic-Clonic; Female; H | 2012 |
Modification of insulin resistance by diazoxide in obese Zucker rats.
Topics: Adipose Tissue; Animals; Blood Glucose; Diazoxide; Energy Intake; Female; Glucose Tolerance Test; In | 1993 |