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diazoxide and Weight Gain

diazoxide has been researched along with Weight Gain in 3 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"Diazoxide-treated obese and lean animals showed significantly lower postabsorptive plasma insulin concentrations (P < 0."5.29Modification of insulin resistance by diazoxide in obese Zucker rats. ( Alemzadeh, R; Maturo, J; Slonim, AE; Zdanowicz, MM, 1993)
"Persistent suppression of hyperinsulinemia in genetically obese (fa/fa) Zucker rats by diazoxide (DZ) reduces food intake and weight gain; improves insulin sensitivity, glycemic control, and lipid profile; and enhances beta(3)-adrenergic function and lipolysis in adipose tissue."3.74Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker rats. ( Alemzadeh, R; Buchholz, M; Karlstad, MD; Tushaus, K, 2008)
"Diazoxide-treated obese and lean animals showed significantly lower postabsorptive plasma insulin concentrations (P < 0."1.29Modification of insulin resistance by diazoxide in obese Zucker rats. ( Alemzadeh, R; Maturo, J; Slonim, AE; Zdanowicz, MM, 1993)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alemzadeh, R2
Karlstad, MD1
Tushaus, K1
Buchholz, M1
Swaminathan, K1
Young, R1
Reid, W1
Slonim, AE1
Zdanowicz, MM1
Maturo, J1

Other Studies

3 other studies available for diazoxide and Weight Gain

ArticleYear
Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker rats.
    Metabolism: clinical and experimental, 2008, Volume: 57, Issue:11

    Topics: Adenylyl Cyclases; Animals; Basal Metabolism; Blood Glucose; Body Composition; Calorimetry, Indirect

2008
The diagnosis was in her birthday party!
    QJM : monthly journal of the Association of Physicians, 2012, Volume: 105, Issue:5

    Topics: Aged, 80 and over; Blood Glucose; C-Peptide; Confusion; Diazoxide; Epilepsy, Tonic-Clonic; Female; H

2012
Modification of insulin resistance by diazoxide in obese Zucker rats.
    Endocrinology, 1993, Volume: 133, Issue:2

    Topics: Adipose Tissue; Animals; Blood Glucose; Diazoxide; Energy Intake; Female; Glucose Tolerance Test; In

1993