diazoxide has been researched along with Uremia in 11 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of uremia on the binding of diazoxide to plasma proteins was studied." | 7.65 | Decreased plasma protein binding of diazoxide in uremia. ( McNay, JL; O'Malley, K; Pruitt, A; Velasco, M, 1975) |
| "The effect of uremia on the binding of diazoxide to plasma proteins was studied." | 3.65 | Decreased plasma protein binding of diazoxide in uremia. ( McNay, JL; O'Malley, K; Pruitt, A; Velasco, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grim, CE | 1 |
| Davidov, M | 2 |
| O'Malley, K | 1 |
| Velasco, M | 1 |
| Pruitt, A | 1 |
| McNay, JL | 1 |
| Kincaid-Smith, P | 1 |
| Fang, P | 1 |
| Laver, MC | 1 |
| Finnerty, FA | 2 |
| Acchiardo, SR | 1 |
| Black, WD | 1 |
| Britt, L | 1 |
| McKeown, JW | 1 |
| Johnson, JG | 1 |
| Hatch, F | 1 |
| Moser, M | 1 |
| McLaine, PN | 1 |
| Drummond, KN | 1 |
| Mroczek, WJ | 1 |
| Gavrilovich, L | 1 |
| Charles, MA | 1 |
| Danforth, E | 1 |
2 reviews available for diazoxide and Uremia
| Article | Year |
|---|---|
Diazoxide: a review of its pharmacological properties and therapeutic use in hypertensive crises.
Topics: Acute Kidney Injury; Animals; Blood Glucose; Cardiovascular Diseases; Cats; Cyclic AMP; Diazoxide; D | 1971 |
Treatment of "hypertensive encephalopathy" (accelerated hypertension). II.
Topics: Antihypertensive Agents; Diazoxide; Glomerulonephritis; Guanethidine; Humans; Hydralazine; Hypertens | 1969 |
1 trial available for diazoxide and Uremia
| Article | Year |
|---|---|
A new look at the treatment of severe hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Chlorothiazide; Clinica | 1973 |
8 other studies available for diazoxide and Uremia
| Article | Year |
|---|---|
Management of malignant hypertension.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretics; Drug | 1980 |
Successful therapy in resistant hypertension.
Topics: Ambulatory Care; Antihypertensive Agents; Diazoxide; Diuretics; Drug Administration Schedule; Drug T | 1976 |
Decreased plasma protein binding of diazoxide in uremia.
Topics: Adult; Blood Proteins; Blood Urea Nitrogen; Creatinine; Diazoxide; Female; Humans; Hypertension; Mal | 1975 |
Aggressive drug therapy in accelerated hypertension.
Topics: Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxide; Ferr | 1974 |
Experience with hemodialysis and renal transplantation in patients with malignant hypertension.
Topics: Acute Kidney Injury; Adult; Brain Diseases; Diazoxide; Diet Therapy; Female; Follow-Up Studies; Furo | 1974 |
Intravenous diazoxide for severe hypertension in childhood.
Topics: Adolescent; Blood Pressure; Child; Child, Preschool; Diazoxide; Female; Glomerulonephritis; Humans; | 1971 |
The value of aggressive therapy in the hypertensive patient with azotemia.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Arteries; Blood Pressure; Blood Urea Nitrogen; | 1969 |
Nonketoacidotic hyperglycemia and coma during intravenous diazoxide therapy in uremia.
Topics: Adult; Depression, Chemical; Diabetic Coma; Diazoxide; Female; Glucose; Humans; Hyperglycemia; Hyper | 1971 |