diazoxide has been researched along with Thrombopenia in 7 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The relatively high prevalence of neutropenia, thrombocytopenia, and hyperuricemia suggests the value in proactively screening for these side effects in children treated with diazoxide." | 7.88 | Prevalence of Adverse Events in Children With Congenital Hyperinsulinism Treated With Diazoxide. ( Avitabile, CM; De León, DD; Givler, S; Herrera, A; Lord, K; Mitteer, L; Vajravelu, ME, 2018) |
| " We diagnosed her with insulinoma and initiated diazoxide treatment to prevent hypoglycemia." | 7.80 | Thrombocytopenia induced by diazoxide in a patient with an insulinoma. ( Adachi, J; Kakihana, K; Mimura, M; Minami, I; Watanabe, T, 2014) |
| " The relatively high prevalence of neutropenia, thrombocytopenia, and hyperuricemia suggests the value in proactively screening for these side effects in children treated with diazoxide." | 3.88 | Prevalence of Adverse Events in Children With Congenital Hyperinsulinism Treated With Diazoxide. ( Avitabile, CM; De León, DD; Givler, S; Herrera, A; Lord, K; Mitteer, L; Vajravelu, ME, 2018) |
| " We diagnosed her with insulinoma and initiated diazoxide treatment to prevent hypoglycemia." | 3.80 | Thrombocytopenia induced by diazoxide in a patient with an insulinoma. ( Adachi, J; Kakihana, K; Mimura, M; Minami, I; Watanabe, T, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thus, KA | 1 |
| den Boogert, WJ | 1 |
| van der Heyden, JC | 1 |
| Herrera, A | 1 |
| Vajravelu, ME | 1 |
| Givler, S | 1 |
| Mitteer, L | 1 |
| Avitabile, CM | 1 |
| Lord, K | 1 |
| De León, DD | 1 |
| Adachi, J | 1 |
| Mimura, M | 1 |
| Minami, I | 1 |
| Kakihana, K | 1 |
| Watanabe, T | 1 |
| Laughon, MM | 1 |
| Chantala, K | 1 |
| Aliaga, S | 1 |
| Herring, AH | 1 |
| Hornik, CP | 1 |
| Hughes, R | 1 |
| Clark, RH | 1 |
| Smith, PB | 1 |
| Combs, JT | 1 |
| Grunt, JA | 1 |
| Brandt, IK | 1 |
| Wales, J | 1 |
| Wolff, F | 1 |
| Todt, H | 1 |
| Mank, H | 1 |
7 other studies available for diazoxide and Thrombopenia
| Article | Year |
|---|---|
Thrombocytopaenia: a serious side effect of diazoxide.
Topics: Antihypertensive Agents; Child, Preschool; Diazoxide; Drug Therapy, Combination; Epistaxis; Hemateme | 2019 |
Prevalence of Adverse Events in Children With Congenital Hyperinsulinism Treated With Diazoxide.
Topics: Congenital Hyperinsulinism; Diazoxide; Dose-Response Relationship, Drug; Drug Administration Schedul | 2018 |
Thrombocytopenia induced by diazoxide in a patient with an insulinoma.
Topics: Biopsy; Diagnosis, Differential; Diazoxide; Female; Humans; Insulinoma; Pancreatic Neoplasms; Thromb | 2014 |
Diuretic exposure in premature infants from 1997 to 2011.
Topics: Acetazolamide; Amiloride; Bronchopulmonary Dysplasia; Chlorothiazide; Cohort Studies; Diazoxide; Diu | 2015 |
Hematologic reactions to diazoxide.
Topics: Adolescent; Agranulocytosis; Diazoxide; Female; Humans; Hypoglycemia; Infant; Thrombocytopenia | 1967 |
Hematological side-effects of diazoxide.
Topics: Adult; Diazoxide; Female; Humans; Leukopenia; Thrombocytopenia | 1967 |
[Treatment of idiopathic hypoglycemia with diazoxide].
Topics: Child; Diazoxide; Hirsutism; Humans; Hypoglycemia; Male; Thrombocytopenia | 1974 |