diazoxide has been researched along with Stroke in 4 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combined hemorrhagic shock (Shock) and unilateral common carotid artery occlusion (Stroke) results in a decrease of oxygen availability to peripheral tissues and organs and the central nervous system (CNS)." | 5.34 | Diazoxide, as a postconditioning and delayed preconditioning trigger, increases HSP25 and HSP70 in the central nervous system following combined cerebral stroke and hemorrhagic shock. ( Alam, H; McCabe, JT; O'Sullivan, JC; Yao, XL, 2007) |
| "Combined hemorrhagic shock (Shock) and unilateral common carotid artery occlusion (Stroke) results in a decrease of oxygen availability to peripheral tissues and organs and the central nervous system (CNS)." | 1.34 | Diazoxide, as a postconditioning and delayed preconditioning trigger, increases HSP25 and HSP70 in the central nervous system following combined cerebral stroke and hemorrhagic shock. ( Alam, H; McCabe, JT; O'Sullivan, JC; Yao, XL, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shimizu, K | 1 |
| Lacza, Z | 1 |
| Rajapakse, N | 1 |
| Horiguchi, T | 1 |
| Snipes, J | 1 |
| Busija, DW | 1 |
| Blanco, M | 1 |
| Lizasoain, I | 1 |
| Sobrino, T | 1 |
| Vivancos, J | 1 |
| Castillo, J | 1 |
| O'Sullivan, JC | 2 |
| Yao, XL | 1 |
| Alam, H | 1 |
| McCabe, JT | 2 |
| Fu, D | 1 |
| Alam, HB | 1 |
4 other studies available for diazoxide and Stroke
| Article | Year |
|---|---|
MitoK(ATP) opener, diazoxide, reduces neuronal damage after middle cerebral artery occlusion in the rat.
Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Diazoxide; Infarction, Middle | 2002 |
Ischemic preconditioning: a novel target for neuroprotective therapy.
Topics: Adenosine Triphosphate; alpha-Linolenic Acid; Animals; Brain; Brain Ischemia; Clinical Trials as Top | 2006 |
Diazoxide, as a postconditioning and delayed preconditioning trigger, increases HSP25 and HSP70 in the central nervous system following combined cerebral stroke and hemorrhagic shock.
Topics: Animals; Blood Pressure; Blotting, Western; Central Nervous System; Cerebral Cortex; Cerebral Hemorr | 2007 |
Diazoxide increases liver and kidney HSP25 and HSP70 after shock and stroke.
Topics: Animals; Diazoxide; Disease Models, Animal; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 He | 2008 |