diazoxide has been researched along with Recrudescence in 6 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazoxide is the main therapeutic agent for persistent hyperinsulinemic hypoglycemia." | 7.77 | Pulmonary hypertension and reopening of the ductus arteriosus in an infant treated with diazoxide. ( Arasli, A; Çetin, II; Demirel, F; Esen, I; Unal, S, 2011) |
| "Diazoxide is the main therapeutic agent for persistent hyperinsulinemic hypoglycemia." | 3.77 | Pulmonary hypertension and reopening of the ductus arteriosus in an infant treated with diazoxide. ( Arasli, A; Çetin, II; Demirel, F; Esen, I; Unal, S, 2011) |
| " We describe a 72-year-old lady who initially presented with episodic hypoglycemia secondary to an insulinoma that was controlled by diazoxide." | 3.69 | Relapse of medically treated insulinoma following the development of thyrotoxicosis: an assessment of potential mechanisms. ( Alberti, KG; Kendall-Taylor, P; Trajano, LR; Walker, M, 1994) |
| "Diazoxide treatment remains the mainstay of medical therapy in long-term management." | 1.30 | Long-term treatment of persistent hyperinsulinaemic hypoglycaemia of infancy with diazoxide: a retrospective review of 77 cases and analysis of efficacy-predicting criteria. ( Brunelle, F; Czernichow, P; Nihoul-Fekete, C; Ogier de Baulny, H; Poggi-Travert, F; Rahier, J; Saudubray, JM; Touati, G, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshida, K | 1 |
| Kawai, M | 1 |
| Marumo, C | 1 |
| Kanazawa, H | 1 |
| Matsukura, T | 1 |
| Kusuda, S | 1 |
| Yorifuji, T | 1 |
| Heike, T | 1 |
| Demirel, F | 1 |
| Unal, S | 1 |
| Çetin, II | 1 |
| Esen, I | 1 |
| Arasli, A | 1 |
| Rappaport, R | 1 |
| Czernichow, P | 2 |
| Giron, BJ | 1 |
| Limal, JM | 1 |
| Lenoir, G | 1 |
| Hatemi, N | 1 |
| Nihoul-Fekete, C | 2 |
| Walker, M | 1 |
| Trajano, LR | 1 |
| Alberti, KG | 1 |
| Kendall-Taylor, P | 1 |
| Touati, G | 1 |
| Poggi-Travert, F | 1 |
| Ogier de Baulny, H | 1 |
| Rahier, J | 1 |
| Brunelle, F | 1 |
| Saudubray, JM | 1 |
| Weidmann, P | 1 |
| Keusch, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use for Diazoxide in the Initial Management of Hypoglycemia in Infants of Diabetic Mothers and Infants Large for Gestation[NCT00994149] | Phase 2/Phase 3 | 100 participants (Anticipated) | Interventional | 2009-10-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for diazoxide and Recrudescence
| Article | Year |
|---|---|
[Treatment of therapy-resistant hypertension].
Topics: Adrenergic beta-Antagonists; Diazoxide; Diuretics; Drug Resistance; Drug Therapy, Combination; Human | 1977 |
5 other studies available for diazoxide and Recrudescence
| Article | Year |
|---|---|
High prevalence of severe circulatory complications with diazoxide in premature infants.
Topics: Birth Weight; Blood Circulation; Congenital Hyperinsulinism; Diazoxide; Ductus Arteriosus, Patent; E | 2014 |
Pulmonary hypertension and reopening of the ductus arteriosus in an infant treated with diazoxide.
Topics: Diagnosis, Differential; Diazoxide; Ductus Arteriosus, Patent; Humans; Hyperinsulinism; Hypertension | 2011 |
[Severe neonatal hypoglycemia due to pancreatic nesidioblastosis. Methods of diagnosis and treatment].
Topics: Blood Glucose; Diagnosis, Differential; Diazoxide; Enteral Nutrition; Follow-Up Studies; Humans; Hyp | 1977 |
Relapse of medically treated insulinoma following the development of thyrotoxicosis: an assessment of potential mechanisms.
Topics: Aged; C-Peptide; Diazoxide; Female; Humans; Hypoglycemia; Insulin; Insulin Resistance; Insulinoma; P | 1994 |
Long-term treatment of persistent hyperinsulinaemic hypoglycaemia of infancy with diazoxide: a retrospective review of 77 cases and analysis of efficacy-predicting criteria.
Topics: Diazoxide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hyperinsu | 1998 |