diazoxide has been researched along with Prediabetic State in 5 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Prediabetic State: The time period before the development of symptomatic diabetes. For example, certain risk factors can be observed in subjects who subsequently develop INSULIN RESISTANCE as in type 2 diabetes (DIABETES MELLITUS, TYPE 2).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, Q | 1 |
| Guo, Z | 1 |
| Yu, Y | 1 |
| Ghatnekar, GS | 1 |
| Ghatnekar, AV | 1 |
| Bu, M | 1 |
| Guo, X | 1 |
| Liu, S | 1 |
| Wang, F | 1 |
| Feng, Z | 1 |
| Bu, S | 1 |
| Alemzadeh, R | 1 |
| Tushaus, K | 1 |
| Sato, Y | 1 |
| Ishihara, F | 1 |
| Hashizume, K | 1 |
| Aizawa, T | 1 |
| Duvina, PL | 1 |
| Taylor, KW | 1 |
5 other studies available for diazoxide and Prediabetic State
| Article | Year |
|---|---|
Diazoxide inhibits aortic endothelial cell apoptosis in diabetic rats via activation of ERK.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Apoptosis; Decanoic Acids; Diazoxide; Endothelium | 2012 |
Diazoxide attenuates insulin secretion and hepatic lipogenesis in zucker diabetic fatty rats.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Body Weight; Diabetes Mellitus, Type 2; Diazo | 2005 |
B-cell hyperresponsiveness to glucose in NIDDM during prediabetes.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Diazoxide; Glucose; Islets of Langerhans; Male; | 1997 |
[9 years of diazoxide therapy in a case of infantile idiopathic hypolglycemia].
Topics: Child; Diazoxide; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Male; Prediabetic State; Se | 1978 |
Diabetes: underlying biochemical lesions.
Topics: Diabetes Mellitus; Diazoxide; Epinephrine; Female; Growth Hormone; Humans; Hyperglycemia; Insulin; I | 1970 |