Page last updated: 2024-10-25

diazoxide and Parkinson Disease

diazoxide has been researched along with Parkinson Disease in 3 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maneuf, YP1
Duty, S1
Hille, CJ1
Crossman, AR1
Brotchie, JM1
Lawson, K1
Pohl, JE1

Reviews

1 review available for diazoxide and Parkinson Disease

ArticleYear
Is there a role for potassium channel openers in neuronal ion channel disorders?
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:10

    Topics: Aminopyridines; Animals; Anticonvulsants; Antihypertensive Agents; Ataxia; Carbamates; Diazoxide; Ep

2000

Other Studies

2 other studies available for diazoxide and Parkinson Disease

ArticleYear
Modulation of GABA transmission by diazoxide and cromakalim in the globus pallidus: implications for the treatment of Parkinson's disease.
    Experimental neurology, 1996, Volume: 139, Issue:1

    Topics: Animals; Antihypertensive Agents; Behavior, Animal; Benzopyrans; Cromakalim; Diazoxide; Disease Mode

1996
Development and management of extrapyramidal symptoms in hypertensive patients treated with diazoxide.
    American heart journal, 1975, Volume: 89, Issue:3

    Topics: Antiparkinson Agents; Anxiety; Basal Ganglia Diseases; Diazoxide; Humans; Hypertension; Parkinson Di

1975