diazoxide has been researched along with Osteoarthritis in 1 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazoxide treatment also modulated the expression levels of OA-related biomarkers." | 5.48 | Diazoxide ameliorates severity of experimental osteoarthritis by activating autophagy via modulation of the osteoarthritis-related biomarkers. ( Bian, Y; Chen, K; Cheng, S; Fu, J; Gu, Y; Meng, Z; Peng, L; Shen, B; Wu, Z; Yao, J; Zeng, D; Zhao, Y, 2018) |
| "Diazoxide treatment also modulated the expression levels of OA-related biomarkers." | 1.48 | Diazoxide ameliorates severity of experimental osteoarthritis by activating autophagy via modulation of the osteoarthritis-related biomarkers. ( Bian, Y; Chen, K; Cheng, S; Fu, J; Gu, Y; Meng, Z; Peng, L; Shen, B; Wu, Z; Yao, J; Zeng, D; Zhao, Y, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meng, Z | 1 |
| Shen, B | 1 |
| Gu, Y | 1 |
| Wu, Z | 1 |
| Yao, J | 1 |
| Bian, Y | 1 |
| Zeng, D | 1 |
| Chen, K | 1 |
| Cheng, S | 1 |
| Fu, J | 1 |
| Peng, L | 1 |
| Zhao, Y | 1 |
1 other study available for diazoxide and Osteoarthritis
| Article | Year |
|---|---|
Diazoxide ameliorates severity of experimental osteoarthritis by activating autophagy via modulation of the osteoarthritis-related biomarkers.
Topics: ADAMTS5 Protein; Animals; Autophagy; Biomarkers; Blotting, Western; Cell Survival; Chondrosarcoma; C | 2018 |