Page last updated: 2024-10-26

diazoxide and Ocular Hypotension

diazoxide has been researched along with Ocular Hypotension in 1 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Ocular Hypotension: Abnormally low intraocular pressure often related to chronic inflammation (uveitis).

Research Excerpts

ExcerptRelevanceReference
"Elevated intraocular pressure is the most prevalent and only treatable risk factor for glaucoma, a degenerative disease of the optic nerve."5.46ATP-sensitive potassium (KATP) channel openers diazoxide and nicorandil lower intraocular pressure by activating the Erk1/2 signaling pathway. ( Bahler, CK; Fautsch, MP; Holman, BH; Roy Chowdhury, U, 2017)
"Elevated intraocular pressure is the most prevalent and only treatable risk factor for glaucoma, a degenerative disease of the optic nerve."1.46ATP-sensitive potassium (KATP) channel openers diazoxide and nicorandil lower intraocular pressure by activating the Erk1/2 signaling pathway. ( Bahler, CK; Fautsch, MP; Holman, BH; Roy Chowdhury, U, 2017)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roy Chowdhury, U1
Bahler, CK1
Holman, BH1
Fautsch, MP1

Other Studies

1 other study available for diazoxide and Ocular Hypotension

ArticleYear
ATP-sensitive potassium (KATP) channel openers diazoxide and nicorandil lower intraocular pressure by activating the Erk1/2 signaling pathway.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Animals; Butadienes; Cells, Cultured; Diazoxide; Enzyme Activation;

2017