Page last updated: 2024-10-25

diazoxide and Nephrotic Syndrome

diazoxide has been researched along with Nephrotic Syndrome in 4 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Research Excerpts

ExcerptRelevanceReference
"The extent and nature of furosemide (F) binding to human albumin (HA) and to the plasma of 6 children with nephrotic syndrome were studied by equilibrium dialysis at 37 degrees C and pH 7."3.65Furosemide binding to human albumin and plasma of nephrotic children. ( Prandota, J; Pruitt, AW, 1975)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prandota, J1
Pruitt, AW1
Wegienka, LC1
Simpson, RG1
Karam, JH1
Forsham, PH1
Rawlins, MD1
McLaine, PN1
Drummond, KN1

Reviews

1 review available for diazoxide and Nephrotic Syndrome

ArticleYear
Variability in response to drugs.
    British medical journal, 1974, Oct-12, Volume: 4, Issue:5936

    Topics: Acute Disease; Acylation; Chlorthalidone; Chronic Disease; Depression; Diazoxide; Digoxin; Dose-Resp

1974

Other Studies

3 other studies available for diazoxide and Nephrotic Syndrome

ArticleYear
Furosemide binding to human albumin and plasma of nephrotic children.
    Clinical pharmacology and therapeutics, 1975, Volume: 17, Issue:2

    Topics: Acetazolamide; Aspirin; Child; Diazoxide; Dose-Response Relationship, Drug; Female; Furosemide; Huma

1975
Clinical experience with diazoxide.
    Annals of the New York Academy of Sciences, 1968, Apr-11, Volume: 150, Issue:2

    Topics: Adenoma, Islet Cell; Adrenal Glands; Adult; Aged; Benzothiadiazines; Blood Glucose; Diabetes Mellitu

1968
Intravenous diazoxide for severe hypertension in childhood.
    The Journal of pediatrics, 1971, Volume: 79, Issue:5

    Topics: Adolescent; Blood Pressure; Child; Child, Preschool; Diazoxide; Female; Glomerulonephritis; Humans;

1971