Page last updated: 2024-10-25

diazoxide and Multiple Sclerosis

diazoxide has been researched along with Multiple Sclerosis in 1 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Virgili, N1
Espinosa-Parrilla, JF1
Mancera, P1
Pastén-Zamorano, A1
Gimeno-Bayon, J1
Rodríguez, MJ1
Mahy, N1
Pugliese, M1

Other Studies

1 other study available for diazoxide and Multiple Sclerosis

ArticleYear
Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis.
    Journal of neuroinflammation, 2011, Nov-02, Volume: 8

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Cell Line; Diazoxi

2011