diazoxide has been researched along with Metabolic Acidosis in 11 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "4 children with ketotic hypoglycemia (KH) showed during a fasting period over 24 hours significant higher decreases of serum alanine levels than normal controls." | 3.66 | [Pathogenesis of ketotic hypoglycemia (author's transl)]. ( Ploier, R; Sommer, R; Tulzer, W, 1979) |
| "Diazoxide treatment could be stopped at the age of 1 month." | 1.27 | Transient lactic acidosis and hyperalaninaemia associated with neonatal hyperinsulinaemic hypoglycaemia: the effects of dichloroacetate (DCA). ( Aynsley-Green, A; Jenkins, PA; Soltész, G; Weindling, AM, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| OKUN, R | 1 |
| RUSSELL, RP | 1 |
| WILSON, WR | 1 |
| Hussain, K | 1 |
| Thornton, PS | 1 |
| Otonkoski, T | 1 |
| Aynsley-Green, A | 2 |
| Weindling, AM | 1 |
| Soltész, G | 1 |
| Jenkins, PA | 1 |
| Ploier, R | 1 |
| Tulzer, W | 1 |
| Sommer, R | 1 |
| Némethová, V | 1 |
| Vigas, M | 1 |
| Lukác, J | 1 |
| Fatranská, M | 1 |
| Káldor, A | 1 |
| Victorin, LH | 1 |
| Thorell, JI | 1 |
| Rosenbloom, AL | 2 |
| Finnerty, FA | 1 |
| Kakaviatos, N | 1 |
| Davidov, M | 1 |
| Drash, A | 1 |
| Wolff, F | 1 |
| Langs, H | 1 |
| Blizzard, RM | 1 |
11 other studies available for diazoxide and Metabolic Acidosis
| Article | Year |
|---|---|
USE OF DIAZOXIDE WITH TRICHLORMETHIAZIDE FOR HYPERTENSION.
Topics: Acidosis; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Body Weight; Diazoxide; Hyperg | 1963 |
Severe transient neonatal hyperinsulinism associated with hyperlactataemia in non-asphyxiated infants.
Topics: Acidosis; Age of Onset; Blood Glucose; C-Peptide; Chlorothiazide; Diazoxide; Diuretics; Fasting; Fat | 2004 |
Transient lactic acidosis and hyperalaninaemia associated with neonatal hyperinsulinaemic hypoglycaemia: the effects of dichloroacetate (DCA).
Topics: Acetates; Acidosis; Alanine; Diazoxide; Dichloroacetic Acid; Humans; Hypoglycemia; Infant; Infant, N | 1983 |
[Pathogenesis of ketotic hypoglycemia (author's transl)].
Topics: Acidosis; Alanine; Child; Child, Preschool; Deoxyglucose; Diazoxide; Epinephrine; Fasting; Female; H | 1979 |
[A case of idiopathic ketotic hypoglycemia successfully treated with diazoxid. (author's transl)].
Topics: Acidosis; Child, Preschool; Diazoxide; Female; Humans; Hypoglycemia; Ketosis | 1977 |
Side effects of some non-antibacterial sulfonamide derivatives.
Topics: Acidosis; Animals; Carbutamide; Diabetes Mellitus; Diazoxide; Diuretics; Drug Synergism; Ethanol; Gl | 1974 |
Plasma insulin and blood glucose during long-term treatment with diazoxide for infant hypoglycemia.
Topics: Acidosis; Blood Glucose; Child, Preschool; Diazoxide; Follow-Up Studies; Glucose; Glucose Tolerance | 1974 |
Ketotic (idiopathic glucagon unresponsive) hypoglycaemia: diazoxide effects.
Topics: Acidosis; Birth Weight; Blood Glucose; Child; Child, Preschool; Diazoxide; Fasting; Female; Glucagon | 1972 |
The long term effect of repeated acute reductions of arterial pressure with diazoxide in patients with severe hypertension.
Topics: Acidosis; Blood Glucose; Diazoxide; Heart; Heart Failure; Humans; Hyperaldosteronism; Hypertension; | 1968 |
Ketotic hypoglycemia. New observations.
Topics: Acidosis; Blood Glucose; Child; Diazoxide; Ephedrine; Glucagon; Glucose; Humans; Hypoglycemia; Keton | 1971 |
Diazoxide-induced diabetes mellitus in a hypopituitary dwarf.
Topics: Acidosis; Antihypertensive Agents; Child; Diabetes Complications; Diazoxide; Dwarfism, Pituitary; Fe | 1966 |