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diazoxide and Liver Neoplasms

diazoxide has been researched along with Liver Neoplasms in 17 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Liver Neoplasms: Tumors or cancer of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"In conclusion, this case may suggest that biologic behavior may differ from histological behavior in insulinoma and platin-based systemic chemotherapy may provide some benefit in patients those who had diazoxide- and octreotide-resistant tumors."3.76Rapidly progressing malignant insulinoma presented with multiple liver metastases: a case report. ( Akkaya, H; Askin, E; Bascil Tutuncu, N; Erdogan, A; Fatih, K; Hampar, A; Kose, F; Ozgur, O; Ozyilkan, O; Tutuncu, NB, 2010)
"Most cases of insulinomas are benign."1.43A malignant cause of hypoglycaemia: a metastatic insulin-secreting pancreatic neuroendocrine carcinoma. ( Berberabe, A; Pagsisihan, D; Palugod-Lopez, EG; Sandoval, MA, 2016)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's4 (23.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Veiguela Blanco, B1
Felechosa, MD1
García Moreira, V1
Sandoval, MA1
Pagsisihan, D1
Berberabe, A1
Palugod-Lopez, EG1
Shao, Y1
Qu, YQ1
Wang, XL1
Song, ZG1
Guo, QH1
Dou, JT1
Ba, JM1
Lü, ZH1
Mu, YM1
Erdogan, A1
Askin, E1
Kose, F1
Fatih, K1
Akkaya, H1
Hampar, A1
Bascil Tutuncu, N1
Tutuncu, NB1
Ozyilkan, O1
Ozgur, O1
Lee, YS1
Paraf, A2
Rautureau, J2
Texier, J1
Wirsching, R1
Spelsberg, F1
Landgraf, R1
Linquette, M1
Fossati, P1
Decoulx, M1
Fourlinnie, JC1
Mariage, P1
Field, JB1
Boyle, C1
Remer, A1
Drapanas, T1
Vachon, A1
Noel, G1
Gauthier, J2
Tete, R1
Berthou, JD1
Benabadji, A1
Hahn, HJ1
Ziegler, M1
Michael, R1
Karg, U1
Langsch, HG1
Dahl, AA1
Mengshoel, S1
Tolloczko, T1
Wasiutyński, A1
Moreaux, J1
Hernandez, C1
Huguet, C1
Hepp, J1
Frerichs, H1
Willms, B1
Kasper, H1
Creutzfeldt, C1
Creutzfeldt, W1
Barthe, J1
Viala, JJ1
Loire, R1
Coeur, P1
Bizollon, C1
Croizat, P1

Reviews

2 reviews available for diazoxide and Liver Neoplasms

ArticleYear
Autoimmune hypoglycemia due to anti-insulin antibodies.
    Medicina clinica, 2018, 06-22, Volume: 150, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Autoimmune Dis

2018
[Islet cell cancer with organic hyperinsulinism. Clinical aspects, diagnosis and therapy].
    Klinische Wochenschrift, 1982, Aug-16, Volume: 60, Issue:16

    Topics: Adenoma; Adenoma, Islet Cell; C-Peptide; Diagnosis, Differential; Diazoxide; Female; Glucagon; Human

1982

Other Studies

15 other studies available for diazoxide and Liver Neoplasms

ArticleYear
A malignant cause of hypoglycaemia: a metastatic insulin-secreting pancreatic neuroendocrine carcinoma.
    BMJ case reports, 2016, Mar-18, Volume: 2016

    Topics: Biopsy; Blood Glucose; C-Peptide; Carcinoma, Neuroendocrine; Diazoxide; Humans; Hyperinsulinism; Hyp

2016
Malignant insulinoma: Report of 6 patients and literature review.
    Neuro endocrinology letters, 2016, Volume: 37, Issue:3

    Topics: Adult; Diazoxide; Diuretics; Female; Humans; Hypoglycemia; Insulinoma; Liver Neoplasms; Male; Middle

2016
Rapidly progressing malignant insulinoma presented with multiple liver metastases: a case report.
    Journal of gastrointestinal cancer, 2010, Volume: 41, Issue:4

    Topics: Antineoplastic Agents; Diazoxide; Fatal Outcome; Female; Humans; Insulinoma; Liver Neoplasms; Middle

2010
Mechanism of apoptosis induced by diazoxide, a K+ channel opener, in HepG2 human hepatoma cells.
    Archives of pharmacal research, 2004, Volume: 27, Issue:3

    Topics: Apoptosis; Calcium Channels; Calcium Signaling; Carcinoma, Hepatocellular; Cell Line, Tumor; Diazoxi

2004
[Hypoglycemia and primary cancer of the liver. Hormonal titers. Action of diazoxide].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1967, Jan-27, Volume: 118, Issue:2

    Topics: Adult; Diazoxide; Glucagon; Growth Hormone; Humans; Hypoglycemia; Insulin; Liver Cirrhosis; Liver Ne

1967
[Organic hypoglycemia due to Langerhans carcinoma. Treatment by diazoxide followed by streptozotocin].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1974, Volume: 19, Issue:5

    Topics: Aged; Carcinoma; Diazoxide; Drug Therapy, Combination; Humans; Hypoglycemia; Islets of Langerhans; L

1974
Clinical and physiologic studies using diazoxide in the treatment of hypoglycemia.
    Annals of the New York Academy of Sciences, 1968, Apr-11, Volume: 150, Issue:2

    Topics: Abdominal Neoplasms; Adenoma, Islet Cell; Adult; Animals; Blood Glucose; Diazoxide; Dogs; Female; Gl

1968
[Current drug therapy of organic hypoglycemia].
    Lyon medical, 1968, Sep-08, Volume: 220, Issue:36

    Topics: Adenoma, Islet Cell; Carcinoma, Hepatocellular; Diazoxide; Female; Glucagon; Humans; Hypoglycemia; L

1968
[Hypoglycemia and primary liver cancer. Hormone levels. Action of diazoxide].
    Revue medico-chirurgicale des maladies du foie, 1967, Volume: 42, Issue:3

    Topics: Adult; Carcinoma, Hepatocellular; Diazoxide; Glucagon; Growth Hormone; Humans; Hypoglycemia; Insulin

1967
[Metastasizing islet cell carcinoma. II. Studies on insulin secretion in vitro].
    Endokrinologie, 1972, Volume: 59, Issue:1

    Topics: Adenoma, Islet Cell; Arginine; Chromatography, Gel; Culture Techniques; Diazoxide; Glucose; Humans;

1972
[Hyperinsulinism due to metastasizing insuloma treated with diazoxide and streptozotocin].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Oct-10, Volume: 92, Issue:28

    Topics: Adenoma, Islet Cell; Blood Glucose; Diazoxide; Female; Humans; Hyperinsulinism; Insulin; Liver Neopl

1972
Diazoxide, encorton and streptozotocin in the treatment of malignant betacytoma.
    Acta medica Polona, 1974, Volume: 15, Issue:1

    Topics: Adenoma, Islet Cell; Adult; Autopsy; Diazoxide; Female; Glucose; Humans; Hypoglycemia; Liver Neoplas

1974
[Hypoglycemic islet cell adenomas, apropos of their arteriographic diagnosis and surgical treatment].
    La Presse medicale, 1969, Jan-18, Volume: 77, Issue:3

    Topics: Adenoma, Islet Cell; Angiography; Celiac Artery; Diazoxide; Duodenum; Humans; Hypoglycemia; Liver Ne

1969
Contribution to the pathogenesis of tumour hypoglycaemia.
    European journal of clinical investigation, 1970, Volume: 1, Issue:1

    Topics: Blood Glucose; Diazoxide; Fatty Acids, Nonesterified; Fibrosarcoma; Gluconeogenesis; Glycolysis; Hum

1970
[Hypoglycemia in the course of secondary liver neoplasm].
    Lyon medical, 1968, Sep-08, Volume: 220, Issue:36

    Topics: Diazoxide; Glucagon; Humans; Hypoglycemia; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis

1968