diazoxide has been researched along with Island Cell Tumor in 116 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of diazoxide in patients with insulinoma has been evaluated using the euglycaemic clamp technique." | 7.67 | Use of euglycaemic clamping in evaluation of diazoxide treatment of insulinoma. ( Páv, J; Skrha, J; Srámková, J; Svacina, S, 1989) |
| " Medical control of the hormonal syndrome with agents such as diazoxide for insulinoma, omeprazole for gastrinoma, and octreotide for vipoma and glucagonoma allows an orderly and thorough investigation for associated endocrinopathies and comorbid medical conditions." | 4.79 | Islet cell tumors. ( Stabile, BE, 1997) |
| "We studied the release of insulin, glucagon, and somatostatin in response to glucose, glyceraldehyde (GA), and alpha-ketoisocaproate (KIC) from rat kidneys containing transplanted insulinomas." | 3.67 | Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney. ( Ferguson, DC; Hoenig, M; Matschinsky, FM, 1984) |
| "The use of diazoxide in patients with insulinoma has been evaluated using the euglycaemic clamp technique." | 3.67 | Use of euglycaemic clamping in evaluation of diazoxide treatment of insulinoma. ( Páv, J; Skrha, J; Srámková, J; Svacina, S, 1989) |
| " The enzyme in the insulinomas, but not that in the nearby pancreases, was inhibited by diazoxide, which is a known inhibitor of insulin secretion in vitro and in vivo." | 3.66 | Increased mitochondrial glycerol phosphate dehydrogenase activity in insulinomas of two hypoglycemic infants. ( MacDonald, MJ; Pellett, JR; Warner, TF, 1983) |
| " In the patient with beta-cell adenoma but not in the one with carcinoma, plasma insulin concentrations decreased promptly and markedly, and blood glucose increased during diazoxide and somatostatin infusion." | 3.66 | Artificial beta-cell application in two cases of insulinoma: a different pattern in beta-cell adenoma and carcinoma. ( Angeletti, G; Brunetti, P; Bueti, A; Calabrese, G; De Angelis, M; Massi-Benedetti, M; Puxeddu, A; Santeusanio, F; Scionti, L, 1979) |
| "The third has occasional fasting hypoglycemia that is treated with diazoxide; he continues to have a seizure disorder and is mentally retarded." | 1.26 | Nesidioblastosis in children. ( Danis, RK; Garvin, PJ; Knight, J; Lewis, JE; Willman, VL, 1980) |
| "To avoid mental retardation, surgical intervention should not be considered as a last resort." | 1.26 | Near-total pancreatectomy in persistent infantile hypoglycemia. ( Moazam, F; Rodgers, BM; Rosenbloom, AL; Talbert, JL, 1982) |
| "Islet cell adenomas are an important consideration in infants and children with hypoglycemia due to hyperinsulinism." | 1.26 | Pancreatic adenomas in infants and children: current surgical management. ( Baker, L; Bishop, HC; Gauderer, M; Stanley, CA, 1978) |
| "In five patients with islet cell tumors and fasting hypoglycemia, basal proinsulin-like component ranged from 26 to 79% of the total immunoreactive insulin." | 1.25 | Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors. ( Gorden, P; Roth, J; Sherman, B, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 109 (93.97) | 18.7374 |
| 1990's | 5 (4.31) | 18.2507 |
| 2000's | 2 (1.72) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martinez-Ibanez, V | 1 |
| Gussinyer, M | 1 |
| Toran, N | 1 |
| Lloret, J | 1 |
| Abad, P | 1 |
| Carrascosa, A | 1 |
| Boix-Ochoa, J | 1 |
| Hussain, K | 1 |
| Cosgrove, KE | 1 |
| Shepherd, RM | 1 |
| Chapman, JC | 1 |
| Swift, SM | 1 |
| Smith, VV | 1 |
| Kassem, SA | 1 |
| Glaser, B | 1 |
| Lindley, KJ | 1 |
| Aynsley-Green, A | 1 |
| Dunne, MJ | 2 |
| LUNDVALL, O | 1 |
| JOHNSSON, S | 1 |
| ERNESTI, M | 2 |
| MITCHELL, ML | 2 |
| RABEN, MS | 2 |
| GILBOA, Y | 1 |
| MARKS, V | 1 |
| ROSE, FC | 1 |
| SAMOLS, E | 1 |
| Turner, RC | 1 |
| Dick, R | 1 |
| Lee, EC | 1 |
| Hoenig, M | 1 |
| Ferguson, DC | 1 |
| Matschinsky, FM | 1 |
| Knight, J | 1 |
| Garvin, PJ | 1 |
| Danis, RK | 1 |
| Lewis, JE | 1 |
| Willman, VL | 1 |
| Burch, PG | 1 |
| McLeskey, CH | 1 |
| Haemers, S | 1 |
| Rottiers, R | 1 |
| Parker, AJ | 1 |
| Musselman, EM | 1 |
| O'Brien, D | 1 |
| Calzoni, D | 1 |
| Guarneri, A | 1 |
| Santamaria, A | 1 |
| Moazam, F | 1 |
| Rodgers, BM | 1 |
| Talbert, JL | 1 |
| Rosenbloom, AL | 1 |
| Wirsching, R | 1 |
| Spelsberg, F | 1 |
| Landgraf, R | 1 |
| Tamburrano, G | 2 |
| Lala, A | 1 |
| Mauceri, M | 1 |
| Leonetti, F | 1 |
| Libianchi, S | 1 |
| Andreani, D | 2 |
| Berger, M | 2 |
| Tsotsalas, M | 1 |
| MacDonald, MJ | 1 |
| Warner, TF | 1 |
| Pellett, JR | 1 |
| Paletto, AE | 1 |
| Morino, F | 1 |
| Boltri, F | 1 |
| Camandona, M | 1 |
| Robecchi, A | 1 |
| Yagi, M | 1 |
| Shiraiwa, K | 1 |
| Abiko, M | 1 |
| Sakuma, H | 1 |
| Hirai, S | 1 |
| Stabile, BE | 1 |
| Fournet, JC | 1 |
| Verkarre, V | 1 |
| De Lonlay, P | 1 |
| Rahier, J | 1 |
| Brunelle, F | 1 |
| Robert, JJ | 1 |
| Nihoul-Fékété, C | 1 |
| Saudubray, JM | 1 |
| Junien, C | 1 |
| Fajans, SS | 5 |
| Floyd, JC | 5 |
| Berger, H | 1 |
| Donzeau, JP | 1 |
| Tricoire, J | 1 |
| Darnaud, J | 1 |
| Arlet, P | 1 |
| Couret, B | 1 |
| Bernardet, P | 1 |
| Gouzi, JL | 1 |
| Vaysse, C | 1 |
| Bonhoure, JP | 1 |
| Calazel, P | 1 |
| Luyckx, AS | 1 |
| Lefebvre, PJ | 1 |
| Scandellari, C | 2 |
| Zaccaria, M | 2 |
| Sicolo, N | 2 |
| Casara, D | 1 |
| Erle, G | 2 |
| Federspil, G | 2 |
| Santeusanio, F | 2 |
| Brunetti, P | 2 |
| Berchtold, P | 1 |
| Cüppers, HJ | 1 |
| Grüneklee, D | 1 |
| Wiegelmann, W | 1 |
| Schütte, M | 1 |
| Gries, FA | 1 |
| Zimmermann, H | 1 |
| Kraybill, WG | 1 |
| Anderson, DD | 1 |
| Lindell, TD | 1 |
| Fletcher, WS | 1 |
| Eastman, RC | 1 |
| Come, SE | 1 |
| Strewler, GJ | 1 |
| Gorden, P | 2 |
| Kahn, CR | 1 |
| Habbick, BF | 1 |
| Cram, RW | 1 |
| Miller, KR | 1 |
| Johnson, RK | 1 |
| Rubens, R | 1 |
| Carlier, A | 1 |
| Thiery, M | 1 |
| Vermeulen, A | 1 |
| Bouderlique, C | 1 |
| Delaitre, R | 1 |
| Bigorgne, JC | 1 |
| Bertrand, G | 1 |
| Fressinaud, P | 1 |
| Guntz, M | 1 |
| Jeschke, R | 1 |
| Romen, W | 1 |
| Thanner, F | 1 |
| Niggemeyer, H | 1 |
| Gauderer, M | 1 |
| Stanley, CA | 1 |
| Baker, L | 2 |
| Bishop, HC | 2 |
| Abascal, J | 1 |
| Farndon, JR | 2 |
| Johnston, ID | 3 |
| Tamburrano, S | 1 |
| Natoli, C | 1 |
| De Palo, C | 1 |
| Zago, E | 1 |
| Le Quesne, LP | 2 |
| Nabarro, JD | 1 |
| Kurtz, A | 1 |
| Zweig, S | 1 |
| Puxeddu, A | 1 |
| Massi-Benedetti, M | 1 |
| Calabrese, G | 1 |
| Angeletti, G | 1 |
| Bueti, A | 1 |
| Scionti, L | 1 |
| De Angelis, M | 1 |
| Nauck, M | 1 |
| Stöckmann, F | 1 |
| Creutzfeldt, W | 2 |
| Skrha, J | 1 |
| Svacina, S | 1 |
| Srámková, J | 1 |
| Páv, J | 1 |
| Bahloul, F | 1 |
| Goode, PN | 1 |
| Anderson, J | 1 |
| Morte, JA | 1 |
| Bell, WE | 1 |
| Samaan, NA | 1 |
| Longnecker, DS | 1 |
| Cohen, MS | 1 |
| Bower, RH | 1 |
| Fidler, SM | 1 |
| Johnsonbaugh, RE | 1 |
| Sode, J | 1 |
| Hunt, PS | 1 |
| Arnould, Y | 1 |
| Ooms, HA | 1 |
| Bastenie, PA | 1 |
| Yoshinaga, T | 1 |
| Graber, AL | 3 |
| Porte, D | 3 |
| Williams, RH | 3 |
| Knopf, RF | 3 |
| Rull, J | 1 |
| Guntsche, EM | 2 |
| Conn, JW | 4 |
| Mengoli, L | 1 |
| Decourt, J | 1 |
| de Gennes, JL | 1 |
| Rull, JA | 1 |
| Thiffault, CA | 2 |
| Salinas, ED | 1 |
| Mangurten, HH | 1 |
| Roberts, SS | 1 |
| Simon, WH | 1 |
| Cornblath, M | 1 |
| Garces, LY | 1 |
| Drash, A | 2 |
| Kenny, FM | 1 |
| Harrison, TS | 1 |
| Bleicher, SJ | 1 |
| Chowdhury, F | 1 |
| Podolsky, S | 1 |
| Fleishman, P | 1 |
| Goldner, MG | 1 |
| Kenny, F | 1 |
| Field, J | 1 |
| Blizzard, R | 1 |
| Langs, H | 1 |
| Wolff, F | 1 |
| Steinke, J | 1 |
| Soeldner, JS | 1 |
| Scaliter, H | 1 |
| Field, JB | 1 |
| Boyle, C | 1 |
| Remer, A | 1 |
| Drapanas, T | 1 |
| Wegienka, LC | 1 |
| Simpson, RG | 1 |
| Karam, JH | 2 |
| Forsham, PH | 2 |
| Vachon, A | 1 |
| Noel, G | 1 |
| Gauthier, J | 1 |
| Tete, R | 1 |
| Berthou, JD | 1 |
| Fontaine, R | 1 |
| Schneegans, E | 1 |
| Haarscher, A | 1 |
| Levy-Silagy, J | 1 |
| Hasselmann, JL | 1 |
| Dorner, M | 1 |
| Assan, R | 4 |
| Tchobroutsky, G | 3 |
| Rosselin, G | 3 |
| Kopf, A | 2 |
| Dérot, M | 3 |
| Welti, JJ | 1 |
| Hanania, G | 1 |
| Lambert, P | 1 |
| Marteau, J | 1 |
| Camillieri, JP | 1 |
| Barbanel, C | 1 |
| Vaysse, J | 1 |
| Faye, C | 1 |
| Aubert, P | 1 |
| Tourneur, R | 1 |
| Vieweg, WV | 1 |
| Cerchio, GM | 1 |
| Onoe, K | 1 |
| Kobashi, K | 1 |
| Fujinaka, S | 1 |
| Yamamoto, T | 1 |
| Hamajo, T | 1 |
| Creutzfelt, W | 1 |
| Bailey, RE | 1 |
| Castro, A | 3 |
| Kramer, RM | 1 |
| Macfarlane, D | 1 |
| Luyckx, A | 3 |
| Zahnd, G | 1 |
| Lefebvre, P | 3 |
| Raithel, D | 1 |
| Mühe, E | 1 |
| Willital, G | 1 |
| Schwartz, JF | 1 |
| Zwiren, GT | 1 |
| Koch, G | 1 |
| Sherman, B | 1 |
| Roth, J | 1 |
| McGrath, WJ | 1 |
| Balsam, MJ | 1 |
| Hummeler, K | 1 |
| Yakovac, WC | 1 |
| Kaye, R | 1 |
| Hahn, HJ | 1 |
| Ziegler, M | 1 |
| Michael, R | 1 |
| Karg, U | 1 |
| Langsch, HG | 1 |
| Götz, M | 1 |
| Rosenmayr, F | 1 |
| Harrell, A | 1 |
| Laurian, L | 1 |
| Ayalon, D | 1 |
| Kisch, E | 1 |
| Cordova, T | 1 |
| Sherman, BM | 1 |
| Pek, S | 1 |
| Kavlie, H | 1 |
| White, TT | 1 |
| Carney, MW | 1 |
| Weinbren, I | 1 |
| Purnell, GV | 1 |
| Sheffield, BF | 1 |
| Schein, PS | 1 |
| Cession-Fossion, A | 1 |
| Dahl, AA | 1 |
| Mengshoel, S | 1 |
| Filipi, CJ | 1 |
| Higgins, GA | 1 |
| Gutman, RA | 1 |
| Fink, G | 1 |
| Shapiro, JR | 1 |
| Selawry, H | 1 |
| Recant, L | 1 |
| Arnold, R | 1 |
| Creutzfeldt, C | 1 |
| Deuticke, U | 1 |
| Frerichs, H | 1 |
| Track, NS | 1 |
| Dyess, K | 1 |
| Buist, N | 1 |
| Potts, J | 1 |
| Patrassi, N | 3 |
| Basoli, A | 3 |
| Mineo, TC | 1 |
| Carboni, M | 3 |
| Stefanini, P | 2 |
| Hofeldt, FD | 1 |
| Dippe, SE | 1 |
| Levin, SR | 1 |
| Blum, MR | 1 |
| Buist, NR | 1 |
| Grampa, G | 1 |
| Gargantini, L | 1 |
| Grigolato, PG | 1 |
| Chiumello, G | 1 |
| Saric, R | 1 |
| Moreau, F | 1 |
| Seguin, G | 1 |
| Cohen, E | 1 |
| Merlet, M | 1 |
| Lorin, JC | 1 |
| Tolloczko, T | 1 |
| Wasiutyński, A | 1 |
| Giddings, AE | 1 |
| Hunninghake, GW | 1 |
| Higuchi, JH | 1 |
| Kyner, JL | 1 |
| Moreaux, J | 1 |
| Hernandez, C | 1 |
| Huguet, C | 1 |
| Hepp, J | 1 |
| Vance, JE | 1 |
| Stoll, RW | 1 |
| Kitabchi, AE | 1 |
| Buchanan, KD | 1 |
| Hollander, D | 1 |
| Börner, E | 1 |
| Biro, G | 1 |
| Kettl, H | 1 |
| Weinges, KF | 1 |
6 reviews available for diazoxide and Island Cell Tumor
| Article | Year |
|---|---|
[Localization of beta-Langerhans tumors secreting hypoglycemics].
Topics: Adenoma, Islet Cell; Angiography; Diazoxide; Humans; Insulin; Insulinoma; Intraoperative Period; Lap | 1983 |
[Islet cell cancer with organic hyperinsulinism. Clinical aspects, diagnosis and therapy].
Topics: Adenoma; Adenoma, Islet Cell; C-Peptide; Diagnosis, Differential; Diazoxide; Female; Glucagon; Human | 1982 |
Islet cell tumors.
Topics: Adenoma, Islet Cell; Diazoxide; Gastrinoma; Humans; Hypoglycemia; Insulinoma; Octreotide; Pancreatic | 1997 |
Diagnosis and medical management of insulinomas.
Topics: Adenoma, Islet Cell; Angiography; Antineoplastic Agents; Benzothiadiazines; Blood Glucose; C-Peptide | 1979 |
[Hypoglycemia and its countermeasures].
Topics: Acute Disease; Adenoma, Islet Cell; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Animals; Bloo | 1969 |
Chemotherapeutic management of the hormone-secreting endocrine malignancies.
Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Ant | 1972 |
1 trial available for diazoxide and Island Cell Tumor
| Article | Year |
|---|---|
[Is the medical treatment of insulinomas justified? Experience with 9 cases].
Topics: Adenoma, Islet Cell; Administration, Oral; Adult; Catheterization; Clinical Trials as Topic; Diazoxi | 1978 |
109 other studies available for diazoxide and Island Cell Tumor
| Article | Year |
|---|---|
Pancreatectomy extension in persistent hyperinsulinaemic hypoglycaemia: a new strategy.
Topics: Adenoma, Islet Cell; Algorithms; Child; Child, Preschool; Diazoxide; Humans; Hyperinsulinism; Hypogl | 2002 |
Uncontrolled insulin secretion from a childhood pancreatic beta-cell adenoma is not due to the functional loss of ATP-sensitive potassium channels.
Topics: Adenoma, Islet Cell; Adenosine Triphosphate; Antihypertensive Agents; Child; Chromosomes, Human, Pai | 2002 |
[INSULOMA TREATED WITH DIAZOXIDE].
Topics: Adenoma, Islet Cell; Antihypertensive Agents; Chlorthalidone; Diabetes Mellitus; Diazoxide; Geriatri | 1965 |
CONTROL OF HYPOGLYCAEMIA WITH DIAZOXIDE AND HUMAN GROWTH HORMONE.
Topics: Adenoma, Islet Cell; Antihypertensive Agents; Bendroflumethiazide; Blood Chemical Analysis; Blood Gl | 1965 |
HYPERINSULINISM DUE TO METASTASIZING INSULINOMA: TREATMENT WITH DIAZOXIDE.
Topics: Adenoma, Islet Cell; Diazoxide; Drug Therapy; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulino | 1965 |
Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney.
Topics: Adenoma, Islet Cell; Animals; Cytochalasin B; Diazoxide; Glucagon; Glucose; Glyceraldehyde; Humans; | 1984 |
Nesidioblastosis in children.
Topics: Adenoma, Islet Cell; Child, Preschool; Diazoxide; Female; Glucagon; Glucose; Humans; Hyperinsulinism | 1980 |
Insulinomas.
Topics: Adenoma, Islet Cell; Diazoxide; Humans; Insulin; Insulin Secretion; Pancreatic Neoplasms | 1981 |
Anesthesia for patients with insulinoma treatment with oral diazoxide.
Topics: Adenoma, Islet Cell; Administration, Oral; Aged; Anesthesia; Diazoxide; Enflurane; Female; Humans; I | 1981 |
Medical treatment of insulinoma.
Topics: Adenoma, Islet Cell; Antineoplastic Agents; Diazoxide; Humans; Insulinoma; Pancreatic Neoplasms | 1981 |
Diazoxide treatment of canine insulinoma.
Topics: Adenoma, Islet Cell; Administration, Oral; Animals; Blood Glucose; Diazoxide; Dog Diseases; Dogs; In | 1981 |
[Occult insulinoma. New prospects for the therapeutic approach].
Topics: Adenoma, Islet Cell; Diazoxide; Humans; Insulinoma; Pancreatic Neoplasms | 1981 |
Near-total pancreatectomy in persistent infantile hypoglycemia.
Topics: Adenoma; Adenoma, Islet Cell; Diazoxide; Female; Humans; Hyperplasia; Hypoglycemia; Infant; Infant, | 1982 |
Diazoxide infusion test in patients with single benign insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Diazoxide; Glucagon; Humans; Insulin; Insulinoma; K | 1983 |
[Therapy of hypoglycemia in the adult].
Topics: Adenoma, Islet Cell; Adult; Diazoxide; Glucagon; Glucose; Humans; Hypoglycemia; Injections, Intraven | 1983 |
Increased mitochondrial glycerol phosphate dehydrogenase activity in insulinomas of two hypoglycemic infants.
Topics: Adenoma, Islet Cell; Diazoxide; Female; Glycerolphosphate Dehydrogenase; Humans; Hypoglycemia; Infan | 1983 |
[Insulinoma: contribution of 21 cases].
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Diazoxide; Female; Humans; Insulinoma; Male; Middle Ag | 1984 |
Familial nesidioblastosis in two sisters.
Topics: Adenoma, Islet Cell; Diazoxide; Fatal Outcome; Female; Humans; Hypoglycemia; Infant, Newborn; Pancre | 1995 |
Loss of imprinted genes and paternal SUR1 mutations lead to hyperinsulinism in focal adenomatous hyperplasia.
Topics: Adenoma, Islet Cell; ATP-Binding Cassette Transporters; Chromosomes, Human, Pair 11; Diazoxide; Drug | 1998 |
Hypoglycemia: a perspective.
Topics: Adenoma, Islet Cell; Citric Acid Cycle; Diabetes Complications; Diazoxide; Female; Glucose; Glucose | 1975 |
[Letter: Obstructive cardiomyopathy revealed by diazoxide].
Topics: Adenoma, Islet Cell; Blood Pressure; Cardiomyopathy, Hypertrophic; Diazoxide; Female; Humans; Middle | 1975 |
Glucagon secretion by the transplantable islet-cell tumor of the Syrian hamster.
Topics: Adenoma, Islet Cell; Animals; Arginine; Blood Glucose; Cricetinae; Diazoxide; Glucagon; Islets of La | 1976 |
Medical treatment of endogenous organic hyperinsulinism.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Child; Chlorpromazine; Diazoxide; Female; Humans; Hyperin | 1976 |
Alpha-cell function in a case of insulinoma.
Topics: Adenoma, Islet Cell; Aged; Blood Glucose; Diazoxide; Female; Glucose Tolerance Test; Humans; Insulin | 1976 |
[Current viewpoints in the clinical diagnosis of insulinomas].
Topics: Adenoma, Islet Cell; Diazoxide; Fasting; Humans; Insulin; Phenytoin; Somatostatin | 1976 |
Islet cell carcinoma of the pancreas: effective therapy with 5-fluorouracil, streptozotocin, and tubercidin.
Topics: Adenoma, Islet Cell; Adult; Diazoxide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Comb | 1976 |
Adriamycin therapy for advanced insulinoma.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diazoxide; Doxorubicin; Drug Therapy, Combination; Female | 1977 |
Neonatal hypoglycemia resulting from islet cell adenomatosis. Successful treatment with total pancreatectomy.
Topics: Adenoma, Islet Cell; Cortisone; Diazoxide; Female; Glucose; Humans; Hypoglycemia; Infant, Newborn; I | 1977 |
Insulinoma in the dog.
Topics: Adenoma, Islet Cell; Animals; Diazoxide; Dog Diseases; Dogs; Glucagon; Hypoglycemia; Insulin; Pancre | 1977 |
Pregnancy complicated by insulinoma. Case report.
Topics: Adenoma, Islet Cell; Adult; Child, Preschool; Diazoxide; Female; Fetus; Humans; Infant; Infant, Newb | 1977 |
[Secreting langerhansian adenoma in children: clinical and biological study. Effects of diazoxide. Arteriographic localization].
Topics: Adenoma, Islet Cell; Adolescent; Diazoxide; Female; Humans; Pancreatic Neoplasms; Radiography | 1977 |
[The disease pattern of the diffuse, nesidioblastic hyperplasia of the pancreatic islets in newborn and infants (author's transl)].
Topics: Adenoma, Islet Cell; Diazoxide; Fatty Acids, Nonesterified; Humans; Hydroxybutyrates; Hypoglycemia; | 1978 |
Pancreatic adenomas in infants and children: current surgical management.
Topics: Adenoma, Islet Cell; Child; Child, Preschool; Diazoxide; Follow-Up Studies; Humans; Hyperinsulinism; | 1978 |
[The insulinomas].
Topics: Adenoma, Islet Cell; Diazoxide; Glucagon; Humans; Hyperplasia; Insulin; Insulin Secretion; Pancreati | 1979 |
[Medical treatment of spontaneous hypoglycemic syndromes].
Topics: Adenoma, Islet Cell; Chlorpromazine; Diazoxide; Fasting; Glucagon; Glucose; Humans; Hypoglycemia; Li | 1979 |
The management of insulin tumours of the pancreas.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Angiography; Blood Glucose; Diazoxide; Female; Humans; | 1979 |
Artificial beta-cell application in two cases of insulinoma: a different pattern in beta-cell adenoma and carcinoma.
Topics: Adenoma; Adenoma, Islet Cell; Artificial Organs; Blood Glucose; Carcinoma; Diagnosis, Differential; | 1979 |
Evaluation of a euglycaemic clamp procedure as a diagnostic test in insulinoma patients.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Blood Glucose; Child; Diazoxide; Evaluation Studies as | 1990 |
Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells.
Topics: Adenoma, Islet Cell; Adenosine Triphosphate; Diazoxide; Glucose; Guanidines; Humans; Insulin; Insuli | 1990 |
Use of euglycaemic clamping in evaluation of diazoxide treatment of insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Aged, 80 and over; Blood Glucose; Diazoxide; Female; Glucose; Home | 1989 |
[Hypoglycemic insular tumor or insulinoma].
Topics: Adenoma, Islet Cell; Diazoxide; Humans; Hypoglycemia; Insulinoma; Nervous System Diseases; Pancreate | 1986 |
Diazoxide in the management of patients with insulinoma.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Child, Preschool; Diazoxide; Edema; Female; Hir | 1986 |
Hypoglycemia due to organic hyperinsulinism in infancy.
Topics: Adenoma, Islet Cell; Adrenal Cortex Hormones; Diazoxide; Female; Humans; Hyperinsulinism; Hyperplasi | 1970 |
Inhibition of insulin release by diphenylhydantoin and diazoxide in a patient with benign insulinoma.
Topics: Adenoma, Islet Cell; Aged; Depression, Chemical; Diazoxide; Glucose; Humans; Insulin; Insulin Secret | 1973 |
Editorial: Streptozotocin for islet-cell carcinoma.
Topics: Acute Kidney Injury; Adenoma, Islet Cell; Diabetes Insipidus; Diazoxide; Drug Evaluation; Humans; Hy | 1973 |
Adult hypoglycaemia associated with neoplasia. A report of three cases with a note on the use of diazoxide.
Topics: Adenoma, Islet Cell; Adult; Antihypertensive Agents; Diazoxide; Female; Fibrosarcoma; Humans; Hypogl | 1966 |
Treatment of insulinoma with streptozotocin.
Topics: Adenoma, Islet Cell; Antibiotics, Antineoplastic; Chlorothiazide; Diazoxide; Humans; Hypoglycemia; M | 1969 |
A morphological study on the mechanism of diazoxide-hyperglycemia (clinical and experimental investigation).
Topics: Adenoma, Islet Cell; Adult; Animals; Child, Preschool; Cytoplasmic Granules; Diazoxide; Female; Gluc | 1969 |
Clinical use of diazoxide and mechanism for its hyperglycemic effects.
Topics: Adenoma, Islet Cell; Adult; Benzothiadiazines; Blood Glucose; Diabetes Mellitus; Diazoxide; Epinephr | 1966 |
Benzothiadiazine suppression of insulin release from normal and abnormal islet tissue in man.
Topics: Adenoma, Islet Cell; Adult; Antihypertensive Agents; Blood Glucose; Chlorpropamide; Diazoxide; Human | 1966 |
Blind pancreatic resection for suspected insulinoma: a review of the problem.
Topics: Adenoma; Adenoma, Islet Cell; Adult; Aged; Diabetes Mellitus; Diazoxide; Female; Humans; Hypoglycemi | 1967 |
[Action of diazoxide in a severe case of hyperinsulinism due to an operated Langerhansian carcinoma complicated by hepatic metastases].
Topics: Adenoma, Islet Cell; Diazoxide; Female; Humans; Hyperinsulinism; Middle Aged; Pancreatectomy; Postop | 1966 |
A difference in mechanism by which leucine and other amino acids induce insulin release.
Topics: Adenoma, Islet Cell; Adult; Amino Acids; Arginine; Blood Glucose; Chlorpropamide; Diazoxide; Female; | 1967 |
Functioning islet cell adenoma in the newborn. Report of a case with failure of diazoxide.
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Blood Glucose; Catecholamines; Corticosterone; Dia | 1968 |
Islet cell tumor in the neonate. Studies in carbohydrate metabolism and therapeutic response.
Topics: Adenoma; Adenoma, Islet Cell; Blood Glucose; Carbohydrate Metabolism; Diazoxide; Diet Therapy; Growt | 1968 |
Further studies on diazoxide suppression of insulin release from abnormal and normal islet tissue in man.
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Catecholamines; Depression, Chemical; Diazoxide; Femal | 1968 |
Inhibition of insulin release by diazoxide and its relation to catecholamine effects in man.
Topics: Adenoma, Islet Cell; Blood Glucose; Catecholamines; Diazoxide; Drug Synergism; Fatty Acids, Nonester | 1968 |
Studies on diazoxide-induced hyperglycemia: an extrapancreatic mechanism.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Child; Coloring Agents; Diabetes Mellitus; Diabetes | 1968 |
Clinical use of diazoxide and studies of the mechanism of its hyperglycemic effects in man.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diabetes Mellitus; Diazoxide; Fatty Acids, Nonesterified; | 1968 |
The therapeutic application of diazoxide in pediatric hypoglycemic states.
Topics: Adenoma, Islet Cell; Blood Glucose; Child; Child, Preschool; Diazoxide; Female; Glucose Tolerance Te | 1968 |
Metabolic effects of diazoxide in normal subjects, patients with diabetes mellitus, and patients with organic hypoglycemia.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Diabetes Mellitus; Diazoxide; Fatty Acids, Nonester | 1968 |
Control of hypoglycemia with diazoxide and hormones.
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Aged; Benzothiadiazines; Blood Glucose; Diazoxide; | 1968 |
Clinical and physiologic studies using diazoxide in the treatment of hypoglycemia.
Topics: Abdominal Neoplasms; Adenoma, Islet Cell; Adult; Animals; Blood Glucose; Diazoxide; Dogs; Female; Gl | 1968 |
Clinical experience with diazoxide.
Topics: Adenoma, Islet Cell; Adrenal Glands; Adult; Aged; Benzothiadiazines; Blood Glucose; Diabetes Mellitu | 1968 |
[Current drug therapy of organic hypoglycemia].
Topics: Adenoma, Islet Cell; Carcinoma, Hepatocellular; Diazoxide; Female; Glucagon; Humans; Hypoglycemia; L | 1968 |
[Apropos of a case of severe hypoglycemia. Present possibilities of diagnosis and treatment].
Topics: Adenoma, Islet Cell; Blood Glucose; Diagnosis, Differential; Diazoxide; Glucocorticoids; Glucose; Gl | 1968 |
[A case of hypoglycemic beta-langerhansian adenoma and secreting parathyroidian adenoma: polyadenomatosis].
Topics: Adenoma; Adenoma, Islet Cell; Arginine; Diazoxide; Female; Glucagon; Growth Hormone; Humans; Hydrone | 1968 |
[Insulin-secreting langerhansian beta-cell tumor in a woman with diabetes mellitus. Case report and literature review].
Topics: Adenoma, Islet Cell; Diabetes Complications; Diabetic Angiopathies; Diazoxide; Humans; Hyperinsulini | 1969 |
[Organic hypoglycemia in association with a malignant tumor and an islet cell adenoma. Determining role of blood insulin determination for the etiologic diagnosis and surgical procedure].
Topics: Adenoma; Adenoma, Islet Cell; Aged; Arginine; Carcinoma; Diazoxide; Female; Glucagon; Glucose Tolera | 1969 |
Pancreatic islet cell carcinoma with hyperinsulinism and probable, ectopic ACTH-MSH secretion.
Topics: Adenoma, Islet Cell; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Blood Glucose; Diazoxide; Gl | 1969 |
[Morphology and histochemistry of insulin secretion].
Topics: Adenoma, Islet Cell; Animals; Blood Glucose; Diazoxide; Histocytochemistry; Humans; Insulin; Insulin | 1968 |
Enhancement of insulin release to acute glycaemic stimulation with depression of basal insulin production rates in insulinoma following diazoxide administration.
Topics: Adenoma, Islet Cell; Adolescent; Blood Glucose; Diazoxide; Diet, Diabetic; Female; Glucose Tolerance | 1970 |
[Diagnosis and treatment of pancreatic insulin-secreting tumors. Apropos of 2 cases observed personally].
Topics: Adenoma, Islet Cell; Administration, Oral; Aged; Diazoxide; Female; Humans; Insulin; Insulin Secreti | 1969 |
[Surgical and conservative treatment of hyperinsulinism].
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Adult; Diagnosis, Differential; Diazoxide; Female; | 1971 |
Islet cell adenomatosis and adenoma in an infant.
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Diazoxide; Glucose; Humans; Hypoglycemia; Infant, | 1971 |
[Islet cell adenoma].
Topics: Adenoma, Islet Cell; Adult; Aged; Angiography; Blood Glucose; Diazoxide; Female; Humans; Hyperinsuli | 1971 |
Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Animals; Child; Chromatography, Gel; Cricetinae; | 1971 |
Surgical grand rounds from the University of Mississippi Medical Center. Management of hyperinsulinism.
Topics: Adenoma, Islet Cell; Diagnosis, Differential; Diazoxide; Dietary Carbohydrates; Female; Glucose Tole | 1971 |
Insulinomas: medical management as a successful alternative to surgical therapy.
Topics: Adenoma, Islet Cell; Child; Diazoxide; Humans; Hypoglycemia; Male; Pancreatic Neoplasms; Radiography | 1972 |
Beta cell adenoma in a child with hypoglycemia controlled with diazoxide.
Topics: Adenoma, Islet Cell; Blood Glucose; Child, Preschool; Diazoxide; Female; Glucose Tolerance Test; Hum | 1972 |
[Metastasizing islet cell carcinoma. II. Studies on insulin secretion in vitro].
Topics: Adenoma, Islet Cell; Arginine; Chromatography, Gel; Culture Techniques; Diazoxide; Glucose; Humans; | 1972 |
[Diazoxide treatment of infantile hypoglycaemia].
Topics: Adenoma, Islet Cell; Diagnosis, Differential; Diazoxide; Hirsutism; Humans; Hypoglycemia; Infant; Ma | 1972 |
Hypoglycemia due to hyperinsulinism treated by streptozotocin and diazoxide.
Topics: Adenoma, Islet Cell; Adult; Anti-Bacterial Agents; Diazoxide; Drug Synergism; Female; Humans; Hyperi | 1972 |
Plasma proinsulin in patients with functioning pancreatic islet cell tumors.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Antigens; Autoanalysis; Chromatography, Gel; Diazoxide | 1972 |
Pancreatic islet beta cell tumors and hyperplasia: experience in 14 Seattle hospitals.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Diazoxide; Female; Humans; Hyperinsulinism; Hyp | 1972 |
Reversal of adult mental subnormality.
Topics: Adenoma, Islet Cell; Adult; Diazoxide; Humans; Intellectual Disability; Intelligence Tests; Male | 1972 |
Pancreatic islet beta cell tumours.
Topics: Adenoma, Islet Cell; Adult; Angiography; Blood Glucose; Diazoxide; Female; Humans; Immunoassay; Insu | 1972 |
Diazoxide.
Topics: Adenoma, Islet Cell; Adult; Catecholamines; Cyclic AMP; Diazoxide; Glucose; Glycogen Storage Disease | 1972 |
Effect of diazoxide on golden hamsters with chronic hypoglycemia due to a transplantable islet-cell tumor.
Topics: Adenoma, Islet Cell; Administration, Oral; Adrenal Glands; Animals; Blood Glucose; Cricetinae; Diazo | 1972 |
[Hyperinsulinism due to metastasizing insuloma treated with diazoxide and streptozotocin].
Topics: Adenoma, Islet Cell; Blood Glucose; Diazoxide; Female; Humans; Hyperinsulinism; Insulin; Liver Neopl | 1972 |
Diagnosis and management of insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Diazoxide; Female; Humans; Male; Middle Aged | 1973 |
Proinsulin and insulin release with a human insulinoma and adjacent nonadenomatous pancreas.
Topics: Adenoma, Islet Cell; Chromatography, Gel; Diazoxide; Epinephrine; Glucose; Humans; In Vitro Techniqu | 1973 |
Biochemical and morphological investigations of 30 human insulinomas. Correlation between the tumour content of insulin and proinsulin-like components and the histological and ultrastructural appearance.
Topics: Adenoma, Islet Cell; Adult; Aged; Chromatography, Gel; Cytoplasmic Granules; Diazoxide; Female; Hist | 1973 |
The effect of diazoxide in children with islet cell adenomas.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Blood Glucose; Body Height; Body Weight; Child; Diazoxide; F | 1973 |
[Indications and medical therapy of hypoglycemic beta-insular].
Topics: Adenoma, Islet Cell; Adrenal Cortex Hormones; Antineoplastic Agents; Carcinoma; Diazoxide; Diuretics | 1973 |
The surgical treatment of occult insulinomas: a review of the problem.
Topics: Adenoma; Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Diazoxide; Female; Follow-Up Studies; Huma | 1974 |
Effects of diphenylhydantoin upon glucose-induced insulin secretion in three patients with insulinoma.
Topics: Adenoma, Islet Cell; Administration, Oral; Adult; Blood Glucose; Diazoxide; Drug Evaluation; Drug Th | 1974 |
The insulin-glucose ration in children with islet cell tumors of the pancreas.
Topics: Adenoma, Islet Cell; Blood Glucose; Child; Diazoxide; Fasting; Glucose Tolerance Test; Humans; Hypog | 1974 |
[Exploration of hypoglycemia].
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Diazoxide; Diet; Fasting; Glucagon; Hormones, Ectopic; | 1974 |
Beta-islet cell tumors of the pancreas: results of a study on 1,067 cases.
Topics: Adenoma, Islet Cell; Adult; Age Factors; Angiography; Child, Preschool; Diazoxide; Female; Glucose T | 1974 |
Hypoglycemia in infancy caused by beta cell nesidioblastosis.
Topics: Adenoma, Islet Cell; Cell Division; Diazoxide; Humans; Hypoglycemia; Infant; Male; Microscopy, Elect | 1974 |
[Prolonged treatment of severe hypoglycemia with diazoxide].
Topics: Adenoma, Islet Cell; Aged; Diazoxide; Drug Eruptions; Edema; Female; Gastrointestinal Diseases; Gout | 1974 |
Diazoxide, encorton and streptozotocin in the treatment of malignant betacytoma.
Topics: Adenoma, Islet Cell; Adult; Autopsy; Diazoxide; Female; Glucose; Humans; Hypoglycemia; Liver Neoplas | 1974 |
Diagnosis and management of insulinoma.
Topics: Adenoma; Adenoma, Islet Cell; Diagnosis, Differential; Diazoxide; Humans; Insulin; Pancreatic Neopla | 1974 |
Fasting hypoglycemia. Diazoxide as a test for endogenous insulin release.
Topics: Adenoma, Islet Cell; Diazoxide; Fasting; Female; Humans; Hypoglycemia; Insulin; Middle Aged | 1974 |
[Hypoglycemic islet cell adenomas, apropos of their arteriographic diagnosis and surgical treatment].
Topics: Adenoma, Islet Cell; Angiography; Celiac Artery; Diazoxide; Duodenum; Humans; Hypoglycemia; Liver Ne | 1969 |
[Endocrine polyadenomatosis. General review and case report].
Topics: Adenoma; Adenoma, Islet Cell; Diazoxide; Female; Humans; Hydronephrosis; Hyperinsulinism; Hypoglycem | 1969 |
Familial nesidioblastosis as the predominant manifestation of multiple endocrine adenomatosis.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Diazoxide; Female; Gastric Mucosa; Gastrins; Glucagon; | 1972 |
[Inhibition of the metabolic and circulatory (cardiovascular) effects of diazoxide through alpha--and beta-receptor blockade].
Topics: Adenoma; Adenoma, Islet Cell; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antigens; B | 1969 |