diazoxide has been researched along with Innate Inflammatory Response in 5 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the role of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain." | 7.79 | The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats. ( Afify, EA; Khedr, MM; Nasser, SA; Omar, AG, 2013) |
| "Doxorubicin-induced cardiotoxicity (DIC) is a common side effect of doxorubicin chemotherapy, and a major mechanism of DIC is inflammation." | 5.91 | Nicorandil Ameliorates Doxorubicin-Induced Cardiotoxicity in Rats, as Evaluated by 7 T Cardiovascular Magnetic Resonance Imaging. ( Gao, F; He, B; Huang, R; Ma, L; Wan, Y; Wang, C; Wang, L; Wang, S; Zhang, M; Zhu, D, 2023) |
| "To investigate the effect of diazoxide administration on liver ischemia/reperfusion injury." | 3.80 | Beneficial effects of adenosine triphosphate-sensitive K+ channel opener on liver ischemia/reperfusion injury. ( Coelho, AM; D'Albuquerque, LA; Machado, MC; Nogueira, MA; Patzina, RA; Pinheiro da Silva, F; Sampietre, SN, 2014) |
| "This study investigated the role of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain." | 3.79 | The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats. ( Afify, EA; Khedr, MM; Nasser, SA; Omar, AG, 2013) |
| "Doxorubicin-induced cardiotoxicity (DIC) is a common side effect of doxorubicin chemotherapy, and a major mechanism of DIC is inflammation." | 1.91 | Nicorandil Ameliorates Doxorubicin-Induced Cardiotoxicity in Rats, as Evaluated by 7 T Cardiovascular Magnetic Resonance Imaging. ( Gao, F; He, B; Huang, R; Ma, L; Wan, Y; Wang, C; Wang, L; Wang, S; Zhang, M; Zhu, D, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Wan, Y | 1 |
| He, B | 1 |
| Zhu, D | 1 |
| Wang, L | 1 |
| Huang, R | 1 |
| Wang, S | 1 |
| Wang, C | 1 |
| Zhang, M | 1 |
| Ma, L | 1 |
| Gao, F | 1 |
| Sáez, JC | 1 |
| Green, C | 1 |
| Nogueira, MA | 1 |
| Coelho, AM | 1 |
| Sampietre, SN | 1 |
| Patzina, RA | 1 |
| Pinheiro da Silva, F | 1 |
| D'Albuquerque, LA | 1 |
| Machado, MC | 1 |
| Afify, EA | 1 |
| Khedr, MM | 1 |
| Omar, AG | 1 |
| Nasser, SA | 1 |
5 other studies available for diazoxide and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Nicorandil Ameliorates Doxorubicin-Induced Cardiotoxicity in Rats, as Evaluated by 7 T Cardiovascular Magnetic Resonance Imaging.
Topics: Animals; Cardiotoxicity; Diazoxide; Doxorubicin; Inflammation; Magnetic Resonance Imaging; Male; Nic | 2023 |
Involvement of Connexin Hemichannels in the Inflammatory Response of Chronic Diseases.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Biological Transport; Calcium; Cations, D | 2018 |
Beneficial effects of adenosine triphosphate-sensitive K+ channel opener on liver ischemia/reperfusion injury.
Topics: Animals; Biomarkers; Diazoxide; Disease Models, Animal; Inflammation; Inflammation Mediators; Liver; | 2014 |
The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats.
Topics: Acute Pain; Analgesics, Opioid; Animals; Chemical and Drug Induced Liver Injury; Diazoxide; Disease | 2013 |